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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tacronex Slution is used to treat atopic dermatitis (eczema). It contains Tacrolimus which works by suppressing the over-reaction of immune cells in the skin to a stimulus. This medicine may sometimes cause side effects such as itching, redness, pain, tingling or burning sensation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

TACROLIMUS-0.1%W/V

Manufacturer/Marketer :

Inex Medicaments Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Tacronex Slution

Tacronex Slution is used to treat moderate to severe atopic dermatitis (eczema). Atopic dermatitis, also known as eczema, is a common skin condition associated with inflamed and itchy skin patches. The symptoms include itchy, dry, flaky, swollen, rough and irritated skin.

Tacronex Slution contains 'Tacrolimus' that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling). 

Use Tacronex Slution as prescribed. You are advised to use Tacronex Slution for as long as your doctor has recommended it for you based on your medical condition. Some people may experience itching, burning sensation, redness, pain or skin tingling. Most of these side effects of Tacronex Slution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex Slution. Avoid alcohol consumption with Tacronex Slution as it may cause flushing (sudden reddening of face or skin that makes you feel warm and hot). Do not cover or wrap the treated area with a bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacronex Slution catches fire and burns easily.

Uses of Tacronex Slution

Treatment of Atopic dermatitis (eczema)

Directions for Use

Wash your hands before and after applying Tacronex Slution. Apply it as a thin layer on the clean and dry affected skin area as prescribed by your doctor. Tacronex Slution is only for external use. Avoid contact with eyes, nose or mouth as it may irritate. If Tacronex Slution accidentally comes in contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Tacronex Slution contains Tacrolimus, an immunosuppressant used to treat moderate to severe atopic dermatitis (eczema) in adults who are not adequately responsive or are intolerant to topical corticosteroids and in children (above 2 years) who failed to respond adequately to topical corticosteroids.  Tacronex Slution suppresses the overreaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling). 

How Tacronex Slution Works

Tacronex Slution contains 'Tacrolimus' that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tacronex Slution

  • Itching

  • Burning sensation
  • Redness
  • Pain
  • Skin tingling

What if I have taken an overdose of Tacronex Slution

Use Tacronex Slution only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Please tell your doctor if you are allergic to Tacrolimus or other medicines. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacronex Slution. Avoid alcohol consumption with Tacronex Slution as it may cause flushing (sudden reddening of face or skin that makes you feel warm and hot). Do not cover or wrap the treated area with a bandage or dressing. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacronex Slution catches fire and burns easily. Please avoid contact with eyes, nose or mouth as it may irritate. Do not shower, bathe or swim immediately after applying Tacronex Slution as it may wash off Tacronex Slution. If Tacronex Slution accidentally comes in contact with these areas, rinse with water thoroughly. Do not swallow Tacronex Slution. In case of accidental swallowing, consult a doctor immediately.

Drug-Drug Interactions

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TacrolimusSaquinavir
Critical
TacrolimusMifepristone
Critical

Drug-Drug Interactions

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TacrolimusSaquinavir
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with saquinavir can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusMifepristone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Mifepristone may significantly increase the blood levels of Tacronex Slution 15 ml, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
TacrolimusThioridazine
Critical
How does the drug interact with Tacronex Slution 15 ml:
Combining Tacronex Slution 15 ml with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusDronedarone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Dronedarone is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Ziprasidone can increase the risk of irregular heart rhythm

How to manage the interaction:
Taking Tacronex Slution 15 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TacrolimusCidofovir
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking cidofovir with Tacronex Slution 15 ml can increase the risk of kidney problems.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor immediately if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
TacrolimusZiprasidone
Critical
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacronex Slution 15 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TacrolimusEtanercept
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking etanercept together with Tacronex Slution 15 ml may increase the risk of serious infections.

How to manage the interaction:
Although taking etanercept and Tacronex Slution 15 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TacrolimusDexlansoprazole
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with dexlansoprazole may significantly increase the blood levels of Tacronex Slution 15 ml which may lead to infections, high sugars, kidney problems, high blood pressure, heart problems, low magnesium levels and hyperkalemia(high potassium levels in the blood),

How to manage the interaction:
Although there is a possible interaction, dexlansoprazole can be taken with Tacronex Slution 15 ml if prescribed by the doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations, muscle spasm, shaking, and seizures(fits). Do not stop using any medications without consulting a doctor.
TacrolimusAtazanavir
Severe
How does the drug interact with Tacronex Slution 15 ml:
Taking Tacronex Slution 15 ml with atazanavir may significantly increase the blood levels of amprenavir, which may lead to kidney problems, high blood pressure, heart problems and hyperkalemia(high potassium levels in blood).

How to manage the interaction:
Although taking Tacronex Slution 15 ml and atazanavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TACROLIMUS-0.1%W/VGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking of grapefruit or grapefruit juice while on Tacronex Slution 15 ml treatment may lead to increased Tacronex Slution 15 ml levels in blood. Avoid or limit grapefruit or grapefruit juice intake during treatment with Tacronex Slution 15 ml.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid), such as apples, cherries, broccoli, spinach, and blueberries.

  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish.
  • Avoid contact of your skin with harsh soaps, detergents, cleaning supplies, dust or sand, wool, synthetic fibres and cigarette smoke.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Tacronex Slution Substitute

Substitutes safety advice
  • Tacroz Forte XL Ointment 40 gm

    22.50per tablet
  • Tacroz Forte Solution 20 ml

    35.10per tablet
  • Tacvido Forte Oral Gel 25 ml

    by AYUR

    26.10per tablet
  • Takfa Forte Lotion 20 ml

    by AYUR

    27.00per tablet
  • Tbis Lotion 20 ml

    38.05per tablet
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Alcohol

Unsafe

Avoid alcohol consumption with Tacronex Slution as it may cause skin or face to become flushed or red and feel hot.

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Pregnancy

Caution

Tacronex Slution is a Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning for pregnancy before using Tacronex Slution.

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Breast Feeding

Consult your doctor

Please consult a doctor if you are a breastfeeding mother before using Tacronex Slution.

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Driving

Safe if prescribed

Tacronex Slution usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have liver problems, consult your doctor before using Tacronex Slution.

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Kidney

Consult your doctor

Please consult your doctor if you have any concerns regarding using Tacronex Slution in patients with kidney problems.

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Children

Caution

Tacronex Slution is not recommended for children below two years of age. For children above two years, Tacronex Slution should be used in dose and duration advised by a doctor only.

FAQs

Tacronex Slution is used to treat moderate to severe atopic dermatitis (eczema).
Tacronex Slution contains Tacrolimus, an immunosuppressant that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thus, it reduces allergic reactions and inflammation (redness and swelling).
Tacronex Slution may cause a burning sensation of the skin at the application site as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.
You are recommended to avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.
You are not recommended to take a shower, swim or bath immediately after applying Tacronex Slution as water may wash off this medicine.
Tacronex Slution is flammable and can catch fire; hence, avoid smoking or going near naked flames after applying the ointment of tacrolimus.
You are recommended to use Tacronex Slution for as long as your doctor has prescribed it. However, if the symptoms persist or worsen even after using Tacronex Slution for two weeks, please consult a doctor.

Country of origin

INDIA

Manufacturer/Marketer address

INEX HOUSE , PLOT NO : 22 , VILLA \'A&B\', SECOND FLOOR , RAJIV STREET, KAMARAJ NAGAR,, Keelkattalai, Chennai, Tamil Nadu 600117
Other Info - TAC0080

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