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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Syzopride-MV2 Tablet is used to treat type 2 diabetes mellitus. It acts by increasing the amount of insulin released by the pancreas. Thus, prevent the blood glucose levels from rising to very high levels and keeps your diabetes under control. It may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE+VOGLIBOSE

Manufacturer/Marketer :

3D Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Syzopride-MV2 Tablet

Syzopride-MV2 Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. The blood glucose level increases and causes symptoms such as frequent urination, increased thirst, and increased hunger; hence, people with type 2 diabetes either do not produce enough insulin or, if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). 

Syzopride-MV2 Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Together, these prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Syzopride-MV2 Tablet should be taken with food to avoid an upset stomach. Based on your medical condition, your doctor will decide for how long you need to take Syzopride-MV2 Tablet . Syzopride-MV2 Tablet may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Most of these side effects do not require medical attention and will resolve gradually over time; however, if you experience these side effects persistently, consult your doctor.

Do not stop taking Syzopride-MV2 Tablet without consulting your doctor, as abrupt stopping may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Syzopride-MV2 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, are planning to get pregnant or are breastfeeding.

Uses of Syzopride-MV2 Tablet

Treatment of Type 2 diabetes mellitus

Directions for Use

Swallow it as a whole with a glass of water. Do not chew or crush it.

Medicinal Benefits

Syzopride-MV2 Tablet contains Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Metformin, which is a 'biguanide', acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. Voglibose, which is an 'alpha-glucosidase inhibitor', prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine. Syzopride-MV2 Tablet prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Syzopride-MV2 Tablet also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy), Syzopride-MV2 Tablet also helps to reduce your chance of having a heart attack or stroke. Being a combination of three drugs, Syzopride-MV2 Tablet  reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

How Syzopride-MV2 Tablet Works

Syzopride-MV2 Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Together, these prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Syzopride-MV2 Tablet

  • Hypoglycaemia (low blood glucose level) 
  • Taste change
  • Nausea
  • Diarrhoea
  • Stomach pain
  • Flatulence
  • Headache
  • Upper respiratory symptoms

What if I have taken an overdose of Syzopride-MV2 Tablet

Do not take more than the prescribed dose of Syzopride-MV2 Tablet as it may cause overdose resulting in mild hypoglycemia (low blood sugar). If you suspect you have taken overdose or have symptoms of overdose, please consult a doctor immediately.

Drug Warnings

Some diabetic patients taking Syzopride-MV2 Tablet may develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid accumulates in the blood. So, your liver and kidney's proper functioning is required for the elimination of excess lactic acid from the blood. You should not take Syzopride-MV2 Tablet if you have kidney disease, as measured by a blood test. Syzopride-MV2 Tablet may lower vitamin B12 levels, so try to have blood tests annually blood and vitamins. Syzopride-MV2 Tablet , when used with or without insulin, has the tendency to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Syzopride-MV2 Tablet may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.

Drug-Drug Interactions

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MetforminIodixanol
Critical
MetforminIofendylate
Critical

Drug-Drug Interactions

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MetforminIodixanol
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iodixanol with Syzopride-MV2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIofendylate
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iofendylate with Syzopride-MV2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Syzopride-MV2 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iotroxic acid with Syzopride-MV2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iopydol with Syzopride-MV2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iopromide with Syzopride-MV2 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Syzopride-MV2 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIocetamic acid
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Syzopride-MV2 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Syzopride-MV2 Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Iopanoic acid with Syzopride-MV2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Syzopride-MV2 Tablet:
Co-administration of Syzopride-MV2 Tablet with Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Taking Syzopride-MV2 Tablet with Iodamide is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, quarter with proteins and quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with wholegrain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Syzopride-MV2 Tablet Substitute

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Alcohol

Unsafe

Taking Syzopride-MV2 Tablet with alcohol can cause hypoglycaemia and can also lead to a rare but life-threatening condition known as Lactic Acidosis. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

As the data around the use of Syzopride-MV2 Tablet in pregnant women is limited, the use of Syzopride-MV2 Tablet in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take Syzopride-MV2 Tablet without a doctor's advice.

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Driving

Caution

Syzopride-MV2 Tablet may cause hypoglycaemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration.

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Liver

Caution

Syzopride-MV2 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor depending on your liver function tests.

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Kidney

Caution

Syzopride-MV2 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor depending on your kidney function tests.

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Children

Caution

Syzopride-MV2 Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Syzopride-MV2 Tablet has not been established in children due to limited evidence. So, only take Syzopride-MV2 Tablet if the doctor has prescribed Syzopride-MV2 Tablet .

FAQs

Syzopride-MV2 Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus.

If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact doctor as it can be a condition of type 2 diabetes.

Hypoglycaemia refers to low blood sugar levels. The symptoms of hypoglycaemia include nausea, headache, irritability, hunger, sweating, dizziness. Syzopride-MV2 Tablet can cause hypoglycaemia. Hypoglycaemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other anti-diabetic medicine along with Syzopride-MV2 Tablet . Diabetics are advised to keep a quick source of sugar like glucose tablets, honey or fruit juice with them.

Syzopride-MV2 Tablet should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

If you feel thirsty after taking Syzopride-MV2 Tablet , it may be because of dehydration as Syzopride-MV2 Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.

Country of origin

India
Other Info - SYZ0007

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