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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Systel Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere's disease. It contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre, thereby preventing nausea and vomiting. Besides this, it also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. It may cause side effects such as dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Marsha Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Systel Tablet

Systel Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness. 

Systel Tablet contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, Systel Tablet also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. 

Take Systel Tablet as prescribed by your doctor. You are advised to take Systel Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling.  Most of these side effects of Systel Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Systel Tablet if you are known to be allergic to Systel Tablet . Systel Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Systel Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Systel Tablet is not recommended for children below 1 year of age. Avoid exposure to direct sunlight while taking Systel Tablet as it may cause the skin to be more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Systel Tablet .

Uses of Systel Tablet

Treatment of Nausea and vomiting in migraine, Schizophrenia, Anxiety disorder.

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Avoid contact of tablet with your skin for a very long time as it may cause swelling, skin redness, and itching (contact skin sensitization).Tablet MD: Place the mouth-dissolving tablet in the mouth and allow it to dissolve. Do not swallow. Avoid handling the tablets with wet hands.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Systel Tablet contains Prochlorperazine, which inhibits dopamine secretion that induces the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Systel Tablet prevents nausea and vomiting. Also, Systel Tablet controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

How Systel Tablet Works

Systel Tablet contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, Systel Tablet also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Systel Tablet

  • Dry mouth

  • Drowsiness
  • Headache
  • Dizziness
  • Stuffy nose
  • Irritability
  • Missed menstrual periods
  • Impotence (difficulty in maintaining an erection)
  • Anxiety
  • Skin rash
  • Skin redness, itching or swelling

What if I have taken an overdose of Systel Tablet

Do not take more than the prescribed dose of Systel Tablet as it may cause overdose. The symptoms of overdose include sleepiness, agitation, uncontrollable shaking of a part of the body, fits, irregular heartbeat, dry mouth, fever, constipation, coma, shuffling walk, difficulty falling asleep or staying asleep. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Systel Tablet if you are known to be allergic to Systel Tablet . Systel Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Systel Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Systel Tablet is not recommended for children below 1 year of age. Avoid consumption of alcohol with Systel Tablet as it may increase adverse effects. You are recommended to avoid contact of Systel Tablet with the skin for a long time as it may cause swelling, redness or itching of the skin. Avoid exposure to direct sunlight while taking Systel Tablet as it may cause skin to more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Systel Tablet .

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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ProchlorperazineMetoclopramide
Critical
How does the drug interact with Systel Tablet 10's:
Coadministration of metoclopramide and Systel Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Systel Tablet 10's together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Systel Tablet 10's:
Coadministration of mesoridazine and Systel Tablet 10's can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Systel Tablet 10's is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
ProchlorperazineDroperidol
Severe
How does the drug interact with Systel Tablet 10's:
Taking Systel Tablet 10's and Droperidol together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Systel Tablet 10's with Droperidol can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.
ProchlorperazineQuinidine
Severe
How does the drug interact with Systel Tablet 10's:
Taking Systel Tablet 10's and Quinidine together can increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Systel Tablet 10's with Quinidine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without first consulting your doctor.
ProchlorperazineKetamine
Severe
How does the drug interact with Systel Tablet 10's:
Coadministration of Systel Tablet 10's with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Systel Tablet 10's with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
ProchlorperazineMoxifloxacin
Severe
How does the drug interact with Systel Tablet 10's:
Using moxifloxacin together with Systel Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Systel Tablet 10's together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience symptoms like an irregular heart rhythm, a heart condition, or sudden dizziness, it is important to call your doctor right away. Do not discontinue any medications without consulting your doctor.
ProchlorperazineZiprasidone
Severe
How does the drug interact with Systel Tablet 10's:
Taking Systel Tablet 10's and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Systel Tablet 10's and Ziprasidone, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
ProchlorperazineArsenic trioxide
Severe
How does the drug interact with Systel Tablet 10's:
Taking Arsenic trioxide and Systel Tablet 10's together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Arsenic trioxide with Systel Tablet 10's together can possibly result in an interaction, but it can be taken if your doctor has advised it. You should contact your doctor immediately if you experience fainting, irregular heartbeats, prolonged diarrhoea or vomiting, sudden dizziness, lightheadedness, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ProchlorperazineVemurafenib
Severe
How does the drug interact with Systel Tablet 10's:
Taking Systel Tablet 10's and Vemurafenib together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Systel Tablet 10's and Vemurafenib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without first talking to your doctor.
ProchlorperazineAnagrelide
Severe
How does the drug interact with Systel Tablet 10's:
Taking Systel Tablet 10's and Anagrelide together can increase the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Systel Tablet 10's and anagrelide, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.

  • If you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.

  • Include more cool beverages in your food like flavoured gelatin, carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

  • Drink any other liquid at least 30 minutes after eating food.

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.

  • Avoid consumption of alcohol as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Systel Tablet Substitute

Substitutes safety advice
  • Acuvert 5 mg Tablet 15's

    8.07per tablet
  • Emikind MD Tablet 10's

    5.76per tablet
  • Acuvert 5 mg Tablet 9's

    6.66per tablet
  • Emidoxyn MD 5 mg Tablet 10's

    by AYUR

    8.82per tablet
  • Stemisil-MD Mango Flavour Tablet 10's

    4.41per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Systel Tablet as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Unsafe

Systel Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the baby such as breathing problems, drowsiness, shaking, muscle stiffness or weakness. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Please consult a doctor if you are a breastfeeding mother as Systel Tablet may not be safe to use in breastfeeding mothers.

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Driving

Caution

Systel Tablet may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Systel Tablet .

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Liver

Caution

Take Systel Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Systel Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Systel Tablet may be given to children above 1 year of age if prescribed by a doctor.

FAQs

Systel Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome.
Systel Tablet contains Prochlorperazine, an antipsychotic drug that works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Systel Tablet prevents nausea and vomiting. Also, Systel Tablet decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia.
Yes, Systel Tablet may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).
Systel Tablet may cause photosensitivity (extreme sensitivity to sunlight). Therefore, it is recommended to avoid exposure to direct sunlight while taking Systel Tablet .
You are not recommended to take Systel Tablet with alprazolam as co-administration of these medicines may increase adverse effects such as confusion, drowsiness, dizziness and difficulty in concentrating. However, please contact your doctor before using Systel Tablet with other medicines.
Systel Tablet should be used with caution in diabetes patients as it may cause an increase in blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Systel Tablet if you are diabetic.
Systel Tablet may cause skin redness, itching and swelling if it comes in contact with the skin for a long time. Therefore, avoid contact of Systel Tablet with the skin for a long time as it may cause contact skin sensitization.
Yes, Systel Tablet does expire. Please verify the expiry date on the pack and it refers to the last day of that month. Systel Tablet should not be used after the expiry date.
No, Systel Tablet is not available over the counter. It is a prescription medication. Because it contains prochlorperazine, which can have significant side effects and requires medical supervision.
Systel Tablet is generally safe to use when taken as prescribed by your doctor. Do not exceed the recommended daily dose. It's important to follow your doctor's instructions.
You can take Systel Tablet for as long as it is advised by your doctor. If you have any difficulty while taking Systel Tablet , please consult your doctor.
No, Systel Tablet is not known to be addictive. However, it's important to use Systel Tablet only as prescribed by your doctor and not to exceed the recommended dosage.
The common side effects of Systel Tablet are dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No. 1935, No. 222, 2Nd Floor, Fountain Electric Market, Bhagirath Palace, Chandni Chowk,New Delhi-110006
Other Info - SYS0025

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