Synriam Tablet belongs to the class of medications called 'anti-malarial primarily used to treat malaria. Synriam Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Synriam Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Synriam Tablet contains 'arterolane maleate' and 'piperaquine phosphate'. Synriam Tablet together treats malaria. They work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

The dose of Synriam Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Synriam Tablet include nausea, vomiting, abdominal pain, loss of appetite, indigestion, cough, dizziness, headache. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Synriam Tablet, please inform your doctor if you are allergic to Synriam Tablet. Do not take Synriam Tablet on your own. Synriam Tablet is used with caution during pregnancy and breastfeeding. Tell your doctor if you are taking medicines other than Synriam Tablet. Synriam Tablet used with caution in liver diseases, kidney diseases. Synriam Tablet should be used with extreme caution in patients suffering from cardiovascular diseases due to the increased risk of severe adverse effects including an irregular heart rhythm. The use of this Synriam Tablet may cause persistent vomiting in some patients.

Synriam Tablet contains 'arterolane maleate' and 'piperaquine phosphate'  belongs to the class of medications called 'anti-malarial primarily used to treat malaria. Synriam Tablet together treats malaria. They work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

• Nausea
• Vomiting
• Abdominal pain
• Loss of appetite
• Indigestion
• Cough
• Dizziness
• Headache

Before starting Synriam Tablet, please inform your doctor if you are allergic to Synriam Tablet. Do not take Synriam Tablet on your own. Synriam Tablet is used with caution during pregnancy and breastfeeding. Tell your doctor if you are taking medicines other than Synriam Tablet. Synriam Tablet used with caution in liver diseases, kidney diseases. Synriam Tablet should be used with extreme caution in patients suffering from cardiovascular diseases due to the increased risk of severe adverse effects including an irregular heart rhythm. The use of this Synriam Tablet may cause persistent vomiting in some patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in these cases based on the clinical condition.

Drug-Drug interaction: Synriam Tablet can interact with pain killers (aspirin), anti-allergic (hydroxyzine), anticancer (tamoxifen), antibiotics (ciprofloxacin, amoxicillin/clavulanate), immunosuppressants (mycophenolate mofetil), antimalarials (primaquine, mefloquine, hydroxychloroquine), antianxiety medicine (pregabalin), anti-epileptic (levetiracetam), antacids (esomeprazole), and anti-anxiety drugs (alprazolam).

Drug-Food interaction: Limit the consumption of grapefruit or grapefruit juice with Synriam Tablet as it can significantly increase the level of this medicine in the blood. 

Drug-Disease interaction: People affected with heart disease (arrhythmias) seizures, liver disease (hepatotoxicity), cardiovascular diseases, kidney diseases should not take Synriam Tablet without doctors consultation.

• ASPIRIN
• HYDROXYZINE
• TAMOXIFEN
• CIPROFLOXACIN
• AMOXICILLIN
• MYCOPHENOLATE MOFETIL
• PRIMAQUINE
• MEFLOQUINE
• HYDROXYCHLOROQUINE
• PREGABALIN
• LEVETIRACETAM
• ESOMEPRAZOLE
• ALPRAZOLAM

• Always take Synriam Tablet with meals for reduced gastric irritation.
• Adequate nutrition is the key to improvement in malaria-induced weakness.
• It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
• Increase fluid and protein intake for malaria-induced weight loss.
• Proper rest and mosquito-free premises are important for the patient to recover.

• Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
•  Avoid mosquito bites by using a mosquito net, insect repellent, and by covering your arms and legs

Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing, and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point, and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure, and jaundice due to excessive red blood cell death due to plasmodium growth inside them.