Synpirox Cream belongs to the class of dermatological medication called topical antifungal primarily used in the treatment of fungal or yeast infections of the skin such as athlete’s foot (affects toes), jock itch (affects the groin area), candidiasis (affects vagina), fungal infections of the fingernails and toenails (an infection that may cause nail discolouration, splitting and pain) and ringworm (affects skin or the scalp) ­­­­. Athlete’s foot, jock itch, and ringworm are fungal infections closely related, whereas candidiasis is a yeast infection caused by Candida albicans. These infections are usually seen in people with weak immune systems. They can spread through skin-to-skin contact.

Synpirox Cream contains ‘ciclopirox’ that works by inhibiting the growth of fungus and reducing the infection. It causes membrane instability by accumulating inside fungal cells and interfering with protein transport across the fungal cell membrane. Thus, Synpirox Cream clears fungal infections and provides relief from cracking, burning, scaling, and itching of the skin caused due to infections.

Synpirox Cream is only for external use. Use or Apply Synpirox Cream as prescribed by your doctor. You are advised to take Synpirox Cream for as long as prescribed, depending on your medical condition. Avoid contact of Synpirox Cream with nose, mouth or eyes. If Synpirox Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience itching, irritation or burning sensation at the application site. Most of these side effects of Synpirox Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Synpirox Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Synpirox Cream. Synpirox Cream is not recommended for children below 10 years of age. If you are using any steroidal cream, lotion or ointment, inform your doctor before taking Synpirox Cream so that the dose may be adjusted. Do not use Synpirox Cream in more than prescribed doses or for a prolonged time as it may cause adverse effects. Do not wrap or cover the treated area with bandages unless advised by your doctor. Do not apply Synpirox Cream to broken skin or cuts. Avoid smoking or going near naked flames as Synpirox Cream catches fire and burns easily. Inform your doctor if you have diabetes, HIV, or AIDS or undergoing chemotherapy and seizures.

Synpirox Cream contains ‘ciclopirox’ is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities, primarily used to treat fungal infections of the skin such as ringworm, jock itch and athlete’s foot, seborrheic dermatitis (dry, flaky skin on the face, scalp, chest, upper back or ears), fungal infections of the fingernails and toenails (an infection that may cause nail discolouration, splitting, and pain) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). It works by stopping the growth of fungus. It causes membrane instability by accumulating inside fungal cells and interfering with protein transport across the fungal cell membrane. Thus, Synpirox Cream clears fungal infections and provides relief from cracking, burning, scaling, and itching of the skin caused due to infections.

• Itching
• Redness
• Irritation
• Burning sensation at the site of application

Avoid contact of Synpirox Cream with nose, mouth or eyes as it may irritate. In case Synpirox Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Synpirox Cream. If you are allergic to Synpirox Cream or any other medicines, please tell your doctor. Do not apply Synpirox Cream to broken skin or cuts. Do not swallow Synpirox Cream. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. Avoid smoking or going near naked flames as Synpirox Cream catches fire and burns easily. Avoid the use of nail varnishes and artificial nails while using Synpirox Cream. Do not share your nail filer to prevent the spread of infection. Do not use more than what is recommended to relieve your symptoms faster, and do not cover the area being treated with Synpirox Cream with a bandage, as this may increase absorption of this medicine and the side effects. Synpirox Cream should be used with caution in people with a weakened immune system due to chronic conditions such as HIV or AIDS and who are receiving chemotherapy, diabetes, or a condition for which you use steroid medication (including skin conditions or breathing disorders).

Drug-Drug Interaction: Synpirox Cream may interact with steroids such as (beclomethasone, budesonide, fluticasone, mometasone, triamcinolone, alclometasone, diflorasone, prednicarbate) oral medications to treat fungal infections such as (fluconazole, itraconazole, ketoconazole, terbinafine,  voriconazole) medications for seizures (carbamazepine, phenytoin, valproic acid, oxcarbazepine, lamotrigine).

Drug-Food Interaction: Inform your doctor if you are taking any herbal supplements, vitamins, or OTC medicines.

Drug-Disease Interaction: If you have or have ever had an organ transplant, chickenpox, cancer, HIV (AIDS), cold sores, diabetes, flaky, itchy, or crusty skin, genital herpes (a sexually transmitted disease that causes painful blisters on reproductive organs), shingles (painful blisters caused by the chickenpox virus), peripheral vascular disease (narrowing of blood vessels in feet, legs, or arms causing numbness, pain, or coldness in that part of the body), psoriasis, and seizures.

• BECLOMETASONE
• BUDESONIDE
• FLUTICASONE
• MOMETASONE
• ALCLOMETASONE TOPICAL
• FLUCONAZOLE
• ITRACONAZOLE
• KETOCONAZOLE
• TERBINAFINE
• VORICONAZOLE
• CARBAMAZEPINE
• PHENYTOIN
• VALPROIC ACID
• OXCARBAZEPINE
• LAMOTRIGINE
• TRIAMCINOLONE
• DIFLORASONE
• PREDNICARBATE

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

• In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.

• Do not scratch the affected skin, as it can spread the infection to other body parts.

• Avoid sharing towels, combs, bedsheets, shoes, or socks with others.

• Wash your bedsheets and towels regularly.

• Before applying Synpirox Cream, clean and dry the affected area.
• Avoid contact of Synpirox Cream with nose, mouth or eyes. In case Synpirox Cream comes in contact with these areas accidentally, rinse with water thoroughly.

Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). Ringworm is a common fungal infection of the skin or scalp that is contagious and causes a rash resembling a worm in a ring shape. Jock itch (also known as tinea cruris) is a fungal infection of the skin that causes an itchy, red rash in warm and moist areas of the body, such as the groin, buttocks, and inner thighs. An athlete’s foot (also known as tinea pedis) is a fungal infection that usually starts between the toes, especially in people who have extremely sweaty feet and wear tight-fitting shoes. It occurs most commonly in athletes. It causes itching, burning, or stinging sensation due to a scaly rash. Seborrheic dermatitis is a skin condition that causes an itchy rash with dry, flaky scales on the skin that contains oil glands such as the scalp, face, back, and upper chest.