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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Synophen 250mg Capsule is used to treat bacterial infections. It contains Chloramphenicol, which kills the infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Kentreck Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Synophen 250mg Capsule

Synophen 250mg Capsule belongs to the group of antibiotic medicines used to treat bacterial infections. It is used to treat typhoid fever and other dangerous infections where other antibiotics are ineffective. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Synophen 250mg Capsule does not work against infections caused by viruses, including colds and flu.
 
Synophen 250mg Capsule contains Chloramphenicol, which works by preventing the synthesis of essential proteins necessary for vital bacterial functions. Thus, it kills the bacteria and helps treat and prevent the spread of infections. Synophen 250mg Capsule is a broad-spectrum antibiotic that is active against both gram-positive and gram-negative bacteria.
 
The dose of Synophen 250mg Capsule can vary depending on your condition and the severity of the infection. In some cases, you may experience common side effects, such as nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Do not take Synophen 250mg Capsule if you are allergic to any of its components or if you are pregnant, planning for pregnancy or breastfeeding. Synophen 250mg Capsule is not recommended for use in children. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Synophen 250mg Capsule

Synophen 250mg Capsule is used to treat bacterial infections.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not chew or break it.Liquid/Syrup/Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the pack's measuring cup/dosing syringe/dropper.

Medicinal Benefits

Synophen 250mg Capsule belongs to the group of antibiotic medicines used to treat bacterial infections. It is used to treat typhoid fever and other dangerous infections where other antibiotics are ineffective. Synophen 250mg Capsule contains ‘Chloramphenicol’ that works by preventing the synthesis of essential proteins necessary for vital bacterial functions. Thus, it kills the bacteria and helps treat and prevent the spread of infections. Synophen 250mg Capsule is a broad-spectrum antibiotic active against both gram-positive and gram-negative bacteria.

How Synophen 250mg Capsule Works

Synophen 250mg Capsule contains Chloramphenicol, which works by preventing the synthesis of essential proteins necessary for vital bacterial functions. Thus, it kills the bacteria and helps treat and prevent the spread of infections. Synophen 250mg Capsule is a broad-spectrum antibiotic that is active against both gram-positive and gram-negative bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Synophen 250mg Capsule

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache

What if I have taken an overdose of Synophen 250mg Capsule

Take Synophen 250mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Synophen 250mg Capsule if you are allergic to any of its components, if you have been recently vaccinated if you have porphyria (a metabolism disorder), minor infection, if you are taking medicines that may suppress the bone marrow, or if you are pregnant or breastfeeding. Inform your doctor if you have liver or kidney problems. Chloramphenicol may cause grey baby syndrome (a condition in which the baby’s skin appears grey); please consult your doctor if you have any concerns. Synophen 250mg Capsule is not recommended for use in children.

Drug-Drug Interactions

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ChloramphenicolTriazolam
Critical
ChloramphenicolFlibanserin
Critical

Drug-Drug Interactions

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ChloramphenicolTriazolam
Critical
How does the drug interact with Synophen 250mg Capsule:
Taking Synophen 250mg Capsule with triazolam can increased the effects of Synophen 250mg Capsule.

How to manage the interaction:
Taking Triazolam with Synophen 250mg Capsule is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolFlibanserin
Critical
How does the drug interact with Synophen 250mg Capsule:
Taking Flibanserin with Synophen 250mg Capsule may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Synophen 250mg Capsule with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.
ChloramphenicolLomitapide
Critical
How does the drug interact with Synophen 250mg Capsule:
Taking lomitapide with Synophen 250mg Capsule can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Synophen 250mg Capsule with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
ChloramphenicolOxycodone
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking oxycodone with Synophen 250mg Capsule, it may increase the blood levels of oxycodone that may increase the risk of side effects.

How to manage the interaction:
Although taking Synophen 250mg Capsule and Oxycodone together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment contact a doctor. Do not stop using any medications without talking to a doctor.
ChloramphenicolGuanfacine
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking Synophen 250mg Capsule and Guanfacine may significantly increase the blood levels and effects of guanfacine.

How to manage the interaction:
There may be a possibility of interaction between Synophen 250mg Capsule and Guanfacine, but it can be taken if prescribed by a doctor. It's important to keep an eye on your blood pressure and heart rate. However, if you experience symptoms such as drowsiness, dizziness, lightheadedness, fainting, headache, palpitations consult a doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolPimozide
Severe
How does the drug interact with Synophen 250mg Capsule:
When Pimozide is taken with Synophen 250mg Capsule, the amount of Pimozide in the blood increases which increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Synophen 250mg Capsule and Pimozide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath contact your doctor right away. Do not stop using any medications without first talking to your doctor.
ChloramphenicolButorphanol
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking Synophen 250mg Capsule and Butorphanol can significantly increase the blood levels of Butorphanol that may increase the risk of side effects.

How to manage the interaction:
Although taking Synophen 250mg Capsule with Butorphanol can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures contact your doctor know. Do not stop using any medications without a doctor's advice.
ChloramphenicolCladribine
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking cladribine together with Synophen 250mg Capsule may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Synophen 250mg Capsule, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact your doctor right away. Do not discontinue any medications without consulting a doctor.
ChloramphenicolIvacaftor
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking Synophen 250mg Capsule and Ivacaftor may increase the blood levels of ivacaftor that increases risk of side effects.

How to manage the interaction:
Although taking Synophen 250mg Capsule and Ivacaftor together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact a doctor. Do not stop using any medications without a doctor's advice.
ChloramphenicolCisapride
Severe
How does the drug interact with Synophen 250mg Capsule:
Taking cisapride together with Synophen 250mg Capsule may significantly increase the blood levels of cisapride that may increase risk of side effects.

How to manage the interaction:
Co-administration of Synophen 250mg Capsule with Cisapride can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately If you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Synophen 250mg Capsule Substitute

Substitutes safety advice
  • Paraxin 250 Capsule 10's

    12.33per tablet
  • ENTEROMYCETIN 250MG CAPSULE

    8.10per tablet
  • Daclor 250mg Tablet

    2.33per tablet
  • Kemiceline 250mg Capsule

    2.16per tablet
  • Chlorocept 250mg Tablet

    0.90per tablet
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Synophen 250mg Capsule. Please consult a doctor if you have concerns.

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Pregnancy

Unsafe

Do not take Synophen 250mg Capsule if you are pregnant as it may harm your foetus. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Do not take Synophen 250mg Capsule if you are breastfeeding as it may pass into breast milk and harm your infant. Please consult your doctor if you have any concerns.

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Driving

Safe if prescribed

Synophen 250mg Capsule does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have liver impairment/liver disease before taking Synophen 250mg Capsule.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment/kidney disease before taking Synophen 250mg Capsule.

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Children

Consult your doctor

Synophen 250mg Capsule should be used for children only if advised by the doctor.

FAQs

Synophen 250mg Capsule works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating and preventing the spread of infections.
Diarrhoea might be a side-effect Synophen 250mg Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Synophen 250mg Capsule even if you feel better, as it is an antibiotic. Leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Synophen 250mg Capsule may cause blood problems in some cases, which could lead to slow healing or infections. Consult your doctor if you have any concerns. Regular blood tests are advised while taking Synophen 250mg Capsule.
Use Synophen 250mg Capsule only as prescribed by the doctor. Do not use Synophen 250mg Capsule for longer durations. Consult your doctor if your condition does not improve or if it worsens.

Country of origin

India
Other Info - SY80250

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