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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Syndopa 110 Tablet is used in the treatment of Parkinson's disease with its symptoms including tremors, spasms, muscle stiffness, and poor muscle control. It contains Levodopa and Carbidopa, which help to control movement. It may cause common side effects such as nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

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3 Days Returnable

Expires on or after :

Jan-27

Syndopa 110 Tablet is a precursor of dopamine (chemical messenger in the brain) primarily used in the treatment of Parkinson’s disease with its symptoms including tremors, spasms, muscle stiffness, and poor muscle control. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion, which causes stiffness, shaking, difficulty in walking, coordination, and balance. In Parkinson's patients, there are low dopamine levels as the nerve cells of the brain (neurons) that produce dopamine begin to die.

Syndopa 110 Tablet contains 'Levodopa' and 'Carbidopa'. Levodopa belongs to the central nervous system agents, while Carbidopa is a decarboxylase inhibitor. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can reach to brain.

Take Syndopa 110 Tablet as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. The most common side effects of Syndopa 110 Tablet are nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Most of these side effects of Syndopa 110 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Syndopa 110 Tablet or any other medicines, please tell your doctor. Levodopa must be discontinued at least 12 hours before starting Syndopa 110 Tablet . If you are pregnant or breastfeeding, it is advised to inform your doctor. If you have glaucoma, asthma, nausea, dizziness, mental illness, breathing problems, daytime sleepiness, involuntary muscle movements, intense urges like gambling, spending money, overeating, or increased sexual urges, please inform your doctor before taking Syndopa 110 Tablet .

Treatment of Parkinson's disease.
Take Syndopa 110 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Syndopa 110 Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. Syndopa 110 Tablet is a combination of two medicines, namely 'Levodopa' and 'Carbidopa'. Levodopa belongs to the class of medications named central nervous system agents, while carbidopa falls under decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. At the same time, Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can effectively reach the brain to block acetylcholine (a chemical messenger in the brain). 

Syndopa 110 Tablet contains 'Levodopa' and 'Carbidopa'. Levodopa belongs to the central nervous system agents, while Carbidopa is a decarboxylase inhibitor. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can reach to brain.
Store in a cool and dry place away from sunlight
  • Nausea

  • Vomiting

  • Confusion

  • Loss of appetite

  • Light-headedness

  • Lowered blood pressure

  • Dyskinesia (uncontrolled/involuntary muscle movement)

Do not take more than the prescribed dose of Syndopa 110 Tablet as it may cause overdose. The symptoms of overdose include irregular heartbeat, severe dizziness, mental or mood changes. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Tell your doctor, if you have any medical history of diabetes, heart attacks, mental illness, stomach ulcers, heart disease, or recently gone through a surgical procedure. After taking Syndopa 110 Tablet , one can feel lightheadedness, so it is advised to avoid any work that needs mental alertness. Patients taking Syndopa 110 Tablet can also have a low level of vitamin B12, increased methylmalonic acid levels. Besides this, a prolonged intake of Syndopa 110 Tablet may lead to greater neuropathy chances (nerve damage). Syndopa 110 Tablet should be given with caution in patients with eye problems (narrow-angle glaucoma), irregular heartbeat (arrhythmia), gastrointestinal bleeding, and psychosis. The use of Syndopa 110 Tablet is restricted if a person takes monoamine oxidase inhibitors (MAOs) or antidepressant drugs like isocarboxazid, phenelzine, selegiline, and tranylcypromine because it can lead to high blood pressure (hypertension) crisis.

verifiedApollotooltip
LevodopaTranylcypromine
Critical
LevodopaPhenelzine
Critical

Drug-Drug Interactions

LevodopaTranylcypromine
Critical
How does the drug interact with Syndopa 110 Tablet 15's:
Taking Tranylcypromine with Syndopa 110 Tablet 15's can increase the risk of high blood pressure

How to manage the interaction:
Taking Syndopa 110 Tablet 15's with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaPhenelzine
Critical
How does the drug interact with Syndopa 110 Tablet 15's:
Using Syndopa 110 Tablet 15's together with phenelzine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Syndopa 110 Tablet 15's with Phenelzine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaProcarbazine
Critical
How does the drug interact with Syndopa 110 Tablet 15's:
Using Syndopa 110 Tablet 15's together with procarbazine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Procarbazine with Syndopa 110 Tablet 15's together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaEsketamine
Severe
How does the drug interact with Syndopa 110 Tablet 15's:
Coadministration of Syndopa 110 Tablet 15's with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Syndopa 110 Tablet 15's and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sleepiness, confusion, difficulty concentrating, and impairment in thinking, judgment consult your doctor immediately. Do not stop using any medications without a doctor's advice.
LevodopaIsocarboxazid
Severe
How does the drug interact with Syndopa 110 Tablet 15's:
Using Syndopa 110 Tablet 15's together with isocarboxazid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Isocarboxazid with Syndopa 110 Tablet 15's together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor right away if you experience symptoms like severe headache, confusion, chest pain, or sudden weakness. Do not stop using any medications without a doctor's advice.
LevodopaGlycopyrronium bromide
Severe
How does the drug interact with Syndopa 110 Tablet 15's:
Coadministration of Syndopa 110 Tablet 15's with glycopyrronium bromide can significantly decrease the blood levels of Syndopa 110 Tablet 15's.

How to manage the interaction:
Although using glycopyrronium bromide and Syndopa 110 Tablet 15's together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without a doctor's advice.
LevodopaAmisulpride
Severe
How does the drug interact with Syndopa 110 Tablet 15's:
Coadministration of Syndopa 110 Tablet 15's with amisulpride may increase the risk and severity of side effects and also reduce the effectiveness of both drugs.

How to manage the interaction:
Although taking amisulpride and Syndopa 110 Tablet 15's can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience drowsiness, low blood pressure, dizziness, and lightheadedness. Do not discontinue any medications without consulting a doctor.
LevodopaLinezolid
Severe
How does the drug interact with Syndopa 110 Tablet 15's:
Using Syndopa 110 Tablet 15's together with linezolid can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between linezolid and Syndopa 110 Tablet 15's, you can take these medicines together if prescribed by a doctor. However, if you experience a sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, you should seek immediate medical attention. Do not stop using any medications without talking to a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

  • Drink plenty of water to avoid headaches due to dehydration. 

  • Limit the consumption of sugar-containing food or food with too many calories but fewer nutrients as it may cause tooth decay.

  • Engage in physical activity like dancing or exercising, which will boost the metabolism and make a person more energetic.

  • Avoid intake of alcoholic beverages with Syndopa 110 Tablet as it can make a person dehydrated and may affect their sleep. This can make it harder for a person’s body to aid the Syndopa 110 Tablet in fighting off infections.

  • It is suggested to take a light meal and avoid high protein foods.

No
ANTIPARKINSON AGENTS
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FAQs

Syndopa 110 Tablet is used in the treatment of Parkinson’s disease with its symptoms including tremors, spasms, muscle stiffness, and poor muscle control.
It is advised to not take Syndopa 110 Tablet glaucoma (damage of optic nerve that is essential for good vision) as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Syndopa 110 Tablet .
It is advised not to stop taking Syndopa 110 Tablet without consulting your doctor as it may lead to a severe condition called withdrawal-emergent hyperpyrexia with symptoms such as confusion, fever, muscle stiffness, changes in heartbeat and breathing. Therefore, take Syndopa 110 Tablet for as long as your doctor has prescribed it and if you experience any of these symptoms while taking Syndopa 110 Tablet , please consult your doctor so that the dose may be gradually reduced.
In some cases, prolonged intake of Syndopa 110 Tablet may lead to a decrease of Vitamin B12 in the body. So, your doctor might recommend regular tests for the Vitamin B12 while using Syndopa 110 Tablet .
The exact effects of birth control pills with Syndopa 110 Tablet is still under research. However, it is best to tell your doctor if you are using any type of hormonal contraception. If a person develops diarrhea and vomiting then they need to change their contraception methods like condoms and other contraceptives.
It has been reported that some patients taking Syndopa 110 Tablet have experienced stomach upset. To avoid such conditions take Syndopa 110 Tablet should be taken with a meal or snack to avoid or lessen the side effects including diarrhea, nausea, and indigestion. Later the body becomes habitual to medicine so a person can take it with a light meal or an empty stomach to get better results. Be sure, to ask the doctor about the best time of taking the medicine.
Drug interactions have been reported when a person takes Methotrexate with Carbidopa. However, clinical research is still going on to know how does Syndopa 110 Tablet affects Methotrexate. One should talk to their doctor for more clarification.
Most people do not face any side effects including jaundice. However, any person who has been taking Syndopa 110 Tablet for a prolonged time then they should consult their doctor immediately if they notice yellowing of skin/eyes or abdominal pain.
Syndopa 110 Tablet is a combination of two medicines namely "Levodopa" and "Carbidopa". Levodopa belongs to the class of medications name as central nervous system agents, While Carbidopa fall in the category of decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. While Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can reach to brain.
Patients with narrow-angle glaucoma should avoid intake of Syndopa 110 Tablet . Levodopa may activate a malignant melanoma (skin cancer), so Syndopa 110 Tablet should not be used in patients with suspicious, undiagnosed skin lesions or a melanoma history. Syndopa 110 Tablet also causes a deficiency of vitamin B12, so patient with low vitamin B12 should not take Syndopa 110 Tablet .
Yes, Syndopa 110 Tablet can be taken on an empty stomach as it helps maximize its effectiveness. Please consult your doctor if you have concerns regarding it.
Yes, Syndopa 110 Tablet may cause dark urine. This is harmless and resolves after stopping Syndopa 110 Tablet . Please consult your doctor if you have concerns regarding it.
Syndopa 110 Tablet is a precursor of dopamine (chemical messenger in the brain) primarily used in the treatment of Parkinson’s symptoms including tremors, spasms, muscle stiffness, and poor muscle control.
The common side effects of Syndopa 110 Tablet include nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled or involuntary muscle movement). Most of these side effects of Syndopa 110 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Syndopa 110 Tablet may cause sleepiness or drowsiness in some individuals. You are not recommended to drive or operate heavy machinery if you are not alert. Please consult your doctor if it is bothering you.
Syndopa 110 Tablet should be stored in a cool and dry place away from sunlight and kept away from children’s reach. Dispose of the expired medication through a medication take-back program or by talking to your pharmacist.
Syndopa 110 Tablet helps control Parkinson's disease but does not cure it. It might take several months for you to notice the benefits of Syndopa 110 Tablet ; therefore, keep taking the medicine for the prescribed duration.
Avoid exceeding the recommended dose as it can cause unpleasant side effects. If you're not feeling well or have concerns, talk to your doctor. The doctor will adjust your dose or suggest a better treatment plan for you.
India
Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - SYN0317

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