Sympara-TD Tablet belongs to the class of analgesics and is used in the symptomatic treatment of moderate to severe pain. Pain can be temporary (acute) or long-lasting (chronic). Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or other organs. While chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, osteoarthritis, and migraine.
Sympara-TD Tablet contains Tramadol, Paracetamol, and Domperidone. Tramadol is an opioid analgesic (pain reliever) that blocks the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) that works by blocking the release of certain chemical messengers that cause fever and pain. Domperidone is an antiemetic that works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Sympara-TD Tablet can be taken as advised by your doctor. Sympara-TD Tablet can be taken with food or after food. Swallow it as a whole with a glass of water. Do not crush or break the Sympara-TD Tablet . People taking Sympara-TD Tablet may experience common side effects like sleepiness, weakness, dizziness, nausea, vomiting, diarrhoea, or constipation. However, all patients may not develop the same side effects. Inform your doctor if you experience any symptoms like chest tightness, breathing difficulties, fever, skin rashes, or increased heart rate. If these side effects persist, stop taking Sympara-TD Tablet and consult your doctor immediately.

Before taking Sympara-TD Tablet , inform your doctor if you are allergic to it. Inform your doctor if you are taking medicines other than the Sympara-TD Tablet . Inform your doctor if you are a pregnant/breastfeeding woman. Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Sympara-TD Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia), cardiac arrest (heart attack), and bleeding disorders.

Sympara-TD Tablet contains Tramadol, Paracetamol, and Domperidone, which belong to the class of analgesics and are used in the symptomatic treatment of moderate to severe pain. Tramadol is an opioid analgesic (pain reliever) that blocks the transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer) that works by blocking the release of certain chemical messengers that cause fever and pain. Domperidone is an antiemetic that works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

• Nausea
• Vomiting
• Constipation
• Dryness in mouth
• Sleepiness
• Weakness
• Dizziness

Inform your doctor if you have known allergies to tramadol, paracetamol or any other active ingredients present in Sympara-TD Tablet . Talk to your doctor before taking Sympara-TD Tablet if you are taking other medicines containing paracetamol or tramadol, using other analgesics, have liver disease, have kidney problems, have asthma or severe lung problems, have central nervous system disorders such as epilepsy or seizures, have alcohol dependence or have any drug dependence.

Drug-Drug interactions: Sympara-TD Tablet may interact with pain medication (pentazocine, naltrexone), monoamine oxidase inhibitors (MAO) (phenelzine, procarbazine, isocarboxazid, rasagiline), antidepressants (fluoxetine, paroxetine), antiepileptics (carbamazepine), HIV drugs (ritonavir), and antifungal (itraconazole).

Drug-Food interactions: No interactions found.

Drug-Disease interactions: Sympara-TD Tablet may interact with liver diseases, heart diseases, respiratory impairment, uncontrolled seizures, alcoholism, and drug abuse.

• CARBAMAZEPINE
• ONDANSETRON
• WARFARIN
• RASAGILINE
• ALCOHOL
• PHENOTHIAZINE
• METOCLOPRAMIDE
• CHOLESTYRAMINE
• QUINIDINE
• ERYTHROMYCIN
• FLUOXETINE

• Do not take alcohol.
• Take adequate rest whenever required.
• Avoid driving or operating heavy machinery.
• Eat a healthy, low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating oversweet food and include more salty food, especially if you have been vomiting.
• Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
• Include more cool beverages in your food, like clear soup, flavoured gelatin, and carbonated beverages. Also, when you drink with a straw, sip slowly to avoid swallowing air that may lead to gas and acidity.

Do not stop using Sympara-TD Tablet without a doctor’s advice. Sudden stopping may cause withdrawal symptoms such as nervousness, mood disturbances, hallucinations, suicidal thoughts, muscle aches, diarrhoea, and nausea.

Pain: Pain is an unpleasant feeling or discomfort that occurs when the nervous system is targeted. People may experience moderate to severe pain due to various conditions such as osteoarthritis, migraine, surgery, or other chronic conditions.

Migraine: A headache of varying intensity, often accompanied by nausea and sensitivity to light and sound. Symptoms include pain on one side of your head, but often on both sides, pain that throbs or pulses, sensitivity to light, sound, and sometimes smell and touch, nausea, and vomiting.

Osteoarthritis: “Osteoarthritis is a disease characterized by cartilage degeneration and its underlying bone within a joint and bony overgrowth. The breakdown of these tissues eventually leads to pain and joint stiffness. The joints most commonly affected are the knees, hips, and those in the hands and spine.