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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:38 PM IST
Susten SR 400 Tablet is used to treat amenorrhoea (absence of menstrual periods) and prevent endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. It contains progesterone which works by replacing oestrogen and progesterone hormone levels in the body. This medicine may sometimes cause side effects such as dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Susten SR 400 Tablet

Susten SR 400 Tablet is used in combination with oestrogen for hormone replacement therapy. Besides this, Susten SR 400 Tablet also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Susten SR 400 Tablet contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Susten SR 400 Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Susten SR 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Susten SR 400 Tablet or any other medicines, please tell your doctor. Avoid taking Susten SR 400 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Susten SR 400 Tablet if you are pregnant, as it may harm the unborn baby. You are advised to use effective birth control methods while taking Susten SR 400 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Susten SR 400 Tablet . Drive only if you are alert, as Susten SR 400 Tablet may cause drowsiness or dizziness.

Uses of Susten SR 400 Tablet

Treatment of Female infertility, Female hormonal imbalance.

Medicinal Benefits

Susten SR 400 Tablet contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Susten SR 400 Tablet is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Susten SR 400 Tablet replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

Directions for Use

Take Susten SR 400 Tablet as prescribed by your doctor. Swallow it with a glass of water. Do not break, crush or chew it. It is best to take Susten SR 400 Tablet at bedtime as it may cause dizziness or drowsiness.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Susten SR 400 Tablet

  • Dizziness
  • Drowsiness
  • Headache
  • Mood changes
  • Diarrhoea
  • Vaginal discharge
  • Joint pain
  • Hot flashes (sudden feeling of warmth) 
  • Constipation

Drug Warnings

If you are allergic to soya, Susten SR 400 Tablet or any other medicines, please tell your doctor. Avoid taking Susten SR 400 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Susten SR 400 Tablet if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Susten SR 400 Tablet to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Susten SR 400 Tablet . Drive only if you are alert as Susten SR 400 Tablet may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Susten SR 400 Tablet . If you are about to undergo any surgery, please inform your doctor that you are taking Susten SR 400 Tablet .

Drug Interactions

Drug-Drug Interaction: Susten SR 400 Tablet may interact with anticonvulsants (carbamazepine, phenytoin, phenobarbital), anti-tuberculosis drugs (rifabutin, rifampicin), anti-HIV drugs (ritonavir, nevirapine, nelfinavir, efavirenz), benzodiazepine (diazepam), water tablet (spironolactone), immunosuppressant (ciclosporin), blood thinners (phenindione), skeletal muscle relaxants (tizanidine), antifungals (terbinafine, ketoconazole, griseofulvin).

Drug-Food Interaction: Susten SR 400 Tablet may interact with St. Jonh’s wort (herbal supplement to treat depression).

Drug-Disease Interaction: Avoid taking Susten SR 400 Tablet if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage  (bleeding in the brain). If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking Susten SR 400 Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • RITONAVIR
  • NEVIRAPINE
  • NELFINAVIR
  • EFAVIRENZ
  • DIAZEPAM
  • SPIRONOLACTONE
  • CICLOSPORIN
  • PHENINDIONE
  • TIZANIDINE
  • TERBINAFINE
  • KETOCONAZOLE
  • GRISEOFULVIN

Habit Forming

No

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.

  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.

  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.

  • Try to be stress-free to improve your mood swings due to hormonal fluctuations.

  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Special Advise

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Disease/Condition Glossary

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to a lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).

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Alcohol

Caution

Interaction of Susten SR 400 Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Susten SR 400 Tablet .

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Pregnancy

Caution

Susten SR 400 Tablet supports pregnancy and helps in the maintenance of pregnancy. However, please consult a doctor if you are pregnant before taking Susten SR 400 Tablet .

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Breast Feeding

Caution

Susten SR 400 Tablet may be excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Susten SR 400 Tablet may cause dizziness or drowsiness. Therefore, avoid driving if you feel dizzy or drowsy after taking Susten SR 400 Tablet .

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Liver

Caution

Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Susten SR 400 Tablet should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Susten SR 400 Tablet is not recommended for children.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - SUS0060

Author Details

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FAQs

Susten SR 400 Tablet is used in combination with oestrogen for hormone replacement therapy. Besides this, Susten SR 400 Tablet also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.
Susten SR 400 Tablet contains Progesterone that works by replacing oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms.
Susten SR 400 Tablet may increase the risk of blood clots especially in patients with a history of blood clots. However, if you experience sudden chest pain, difficulty in breathing or painful swelling and redness of legs, stop taking Susten SR 400 Tablet and consult a doctor immediately as these might be signs of blood clot.
If oestrogen is used alone for hormone replacement therapy, it may increase the risk of endometrial hyperplasia (excessive thickening of uterus lining) and endometrial cancer (cancer of the womb). Oestrogen in combination with Susten SR 400 Tablet reduces this risk.
You are recommended to inform your doctor that you are taking Susten SR 400 Tablet as you may need to stop taking Susten SR 400 Tablet 4 to 6 weeks before surgery to decrease the risk of blood clot.
Susten SR 400 Tablet may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.
Susten SR 400 Tablet is not a contraceptive. You are recommended to use additional contraceptive methods to prevent pregnancy while taking Susten SR 400 Tablet .
Susten SR 400 Tablet should be swallowed as a whole with water. Do not crush or chew it.
Susten SR 400 Tablet is a hormone extracted from plants and is chemically identical to human progesterone.
Yes, Susten SR 400 Tablet can be taken daily. Usually, it is taken once everyday in the evening or at bedtime.
Some people might gain weight due to other reasons while taking Susten SR 400 Tablet . Consult the doctor if you notice weight gain during Susten SR 400 Tablet therapy.
Yes, Susten SR 400 Tablet is safe if taken in the dose and duration prescribed by the doctor.
Progesterone plays a vital role in fertility. It improves the chances of becoming and staying pregnant by preparing the uterus lining.
Susten SR 400 Tablet may cause side effects like dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. If the side effects persist or worsen, please consult your doctor.

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