Suphie-35 Tablet 21's is used to treat moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age with PCOS (Polycystic ovary syndrome). It should be used only if your skin condition has not improved, even after topical or antibiotic treatment. Due to its contraceptive properties, it will only be prescribed for you if your doctor considers that treatment with a hormonal contraceptive is appropriate. 

Suphie-35 Tablet 21's contains Ethinylestradiol and Cyproterone, which work by blocking the production of androgens (male hormones) in the ovaries. Thereby, it helps reduce acne and hair growth.

In some cases, Suphie-35 Tablet 21's may cause nausea, abdominal pain, headache, weight gain and mood changes. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.

Do not take Suphie-35 Tablet 21's if you are allergic to any of its components or if you are pregnant, might be pregnant or breastfeeding. Suphie-35 Tablet 21's inhibits ovulation and prevents conception; therefore, avoid using additional hormonal contraceptives whilst on treatment with Suphie-35 Tablet 21's. Keep the doctor informed about your health conditions and medications to rule out any side effects/interactions.

Suphie-35 Tablet 21's contains Ethinylestradiol and Cyproterone used to treat signs of androgenisation in women. It is indicated in the treatment of moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age. Suphie-35 Tablet 21's works by blocking the production of androgens (male hormones) in the ovaries. Thereby, it helps reduce acne and hair growth.

• Nausea
• Abdominal pain
• Weight gain
• Headache
• Mood changes
• Breast pain and tenderness

Do not use Suphie-35 Tablet 21's if you are allergic to any of its components, if you are using another hormonal contraception, are pregnant, might be pregnant or breastfeeding, or have had breast cancer, blood circulation problems/blood clots, heart attack or stroke. Inform the doctor if you have high blood pressure/uncontrolled blood pressure, high cholesterol, migraine, severe liver disease, liver tumours, depression, diabetes, inflammation of the pancreas, chloasma (brown patches on the skin), angioedema or hepatitis. Suphie-35 Tablet 21's may increase the risk of having blood clots; seek medical attention if you notice symptoms of blood clots (migraine/long-lasting headache, changes in your eye-sight, hearing or speech, severe pain in the abdomen, severe pain or swelling in legs, breathlessness, unusual sudden coughing, severe pain and tightness in the chest which may reach the left arm, dizziness/fainting, or sudden weakness/numbness). 

Drug-Drug Interactions: Inform the doctor if you are taking anticonvulsants (primidone, phenytoin, carbamazepine, oxcarbazepine, topiramate, felbamate), anti-HIV (ritonavir, nelfinavir, nevirapine), anti-fungal (griseofulvin), antimicrobial (rifampicin), sedatives or herbal remedy (St. John’s wort).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have/had blood clot problems, breast cancer, high blood pressure, heart attack or stroke.

• PRIMIDONE
• PHENYTOIN
• CARBAMAZEPINE
• OXCARBAZEPINE
• TOPIRAMATE
• FELBAMATE
• RITONAVIR
• NELFINAVIR
• NEVIRAPINE
• GRISEOFULVIN
• RIFAMPICIN
• ST JOHN'S WORT

• Avoid processed food, milk and dairy products.
• Always wash off your makeup before sleeping. Avoid going to bed with makeup on.
• Exercise regularly and eat healthy food.
• Avoid smoking and alcohol consumption.
• Protect your skin from sun damage by using sunscreen.
• Drink plenty of water.

• Your doctor may advise regular check-ups whilst on treatment with Suphie-35 Tablet 21's.
• Check your breasts and nipples every month and consult the doctor if you notice anything odd, such as lumps or dimpling of the skin.
• Inform the doctor that you are taking Suphie-35 Tablet 21's if you are due to undergo any tests or surgery.

Acne vulgaris: Acne is a skin condition that involves papules (inflamed pimples), pustules (spots containing pus), erythema (skin redness), and tenderness. It mainly occurs on the face, back, and chest. Acne occurs due to plugging of hair follicles with oil and dead skin cells. Symptoms include pimples, bumps, and uninflamed blackheads.

Hirsutism: Hirsutism is unwanted male-pattern hair growth in women, which occurs due to excess male hormones called androgens. This causes excess amounts of stiff and pigmented hair on a woman’s face, back and chest.