Sufrate LA Cream is used in the treatment of anal fissures (small tear in the anus lining), fistula (abnormal skin opening near the anus) and piles (inflamed and swollen veins in the rectum). Anorectal disorders occur at the junction of the anal canal and the rectum, including haemorrhoids, abscesses, fistula, fissures, anal itching and warts. It is characterized by the accumulation of veins at the anus with frequent mucus and bleeding while straining for stool passage. 

Sufrate LA Cream is a combination of three drugs: Lidocaine (local anaesthetic), Metronidazole (antibiotic) and Sucralfate (protectant). Lidocaine is a local anaesthetic that decreases pain sensation by preventing pain signal transmission from nerves to the brain.  Metronidazole belongs to the class of antibiotics that prevents bacterial infection caused due to exposed skin surface of the anus. Sucralfate belongs to the class of protectants that form a protective layer over the affected area of skin, thereby preventing pain, burning sensation and inflammation in the anus. Thus together, Sufrate LA Cream promotes the healing of fissures, helps in forming new healthy skin and minimises infection and pain around the anal canal. 

Sufrate LA Cream is for external use only. Use Sufrate LA Cream as prescribed by your doctor. Avoid contact of Sufrate LA Cream with nose, ears, mouth or eyes. In case Sufrate LA Cream comes in contact with these areas accidentally, rinse with water thoroughly. Your doctor will advise you how often you take Sufrate LA Cream based on your medical condition. In some cases, you may experience a skin rash, mild irritation, tingling or burning sensation. Most of these side effects of Sufrate LA Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sufrate LA Cream or any other medicines, please tell your doctor. Sufrate LA Cream is for external use only. Avoid contact of Sufrate LA Cream with nose, ears, mouth or eyes. In case Sufrate LA Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, please inform your doctor before taking Sufrate LA Cream. Do not apply Sufrate LA Cream in large amounts or use it for a longer time than prescribed, as it does not give quick or better results but increases the risk of side effects. Do not swallow Sufrate LA Cream. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Sufrate LA Cream.

Sufrate LA Cream is a combination of three drugs: Lidocaine, Metronidazole, and Sucralfate. Lidocaine belongs to the class of local anaesthetics that decreases pain sensation by preventing the transmission of pain signals from nerves to the brain. Metronidazole belongs to the class of antibiotics that works by damaging the DNA (genetic material) of bacteria and protozoa and killing them. Thereby prevents infection in the anal region. Sucralfate belongs to the class of protectants that works by forming a protective layer over the affected area of skin and prevents pain, irritation, or burning sensation in the anus. Thus, it promotes the healing of fissures and the formation of new healthy skin.

• Skin rash

• Mild irritation
• Tingling
• Burning sensation
• Diarrhoea
• Dry mouth

If you are allergic to Sufrate LA Cream or any other medicines, please tell your doctor. Sufrate LA Cream is for external use only. Avoid contact of Sufrate LA Cream with nose, ears, mouth, or eyes. In case Sufrate LA Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, please inform your doctor before taking Sufrate LA Cream. Do not apply Sufrate LA Cream on cuts, wounds, grazes, or raw or blistered skin. You are recommended to avoid rubbing, scratching, or exposure to extreme cold and hot until the anesthetic effect has worn off. Avoid using Sufrate LA Cream in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects. Do not swallow Sufrate LA Cream. In case of accidental swallowing, please consult a doctor immediately. If you have kidney or liver disease, diabetes, or blood disorders, inform your doctor before taking Sufrate LA Cream.

Drug-Drug Interaction: Sufrate LA Cream may have interaction with medicines to treat irregular heartbeat (amiodarone, tocainide, mexiletine), high blood pressure-lowering medicines (propranolol, metoprolol), medicines to treat stomach ulcers or heartburn (cimetidine), tuberculosis vaccine, vitamin (ascorbic acid), blood thinners (warfarin, dicoumarin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have kidney or liver disease, diabetes or blood disorders, inform your doctor before taking Sufrate LA Cream.

• AMIODARONE
• MEXILETINE
• PROPRANOLOL
• METOPROLOL
• CIMETIDINE
• ASCORBIC ACID
• WARFARIN
• TOCAINIDE
• TUBERCULOSIS VACCINE
• DICOUMAROL

• Drink plenty of fluids to prevent constipation.

• Take fiber supplements and fiber-rich foods such as raw fruits and vegetables.

• Take a sitz bath (a warm water bath covering hips and buttocks) to relax anal muscles, increase blood flow to the anorectal area and relieve irritation.

• Avoid straining during bowel movements as it may create pressure and lead to the opening of a healing tear or cause a new tear.

Follow WASH regimen for anorectal diseases like piles:

• W stands for a warm sitz bath for 10 minutes.

• A stands for analgesic and painkiller.

• S stands for stool softener.

• H stands for hemorrhoidal cream.  

Anal Fissure: It is a small cut or tear in the lining of the anus. Sometimes, the crack may be so deep that it exposes the muscle tissue underneath. It occurs mostly when passing hard or large stools, diarrhea, or chronic constipation. The crack in the skin leads to severe pain and bleeding during and after bowel movements. Anal fissure symptoms include sharp pain in the anal region during bowel movements, itching or burning sensation in the anal region, a visible tear in the skin around the anus, streaks of blood on stools, a skin tag or small lumps or skin next to the tear.

Piles: It occurs when anus tissue and vein become inflamed and swollen. The size of piles can vary from small to large, either found inside or outside the anus. Piles can occur due to many reasons like chronic constipation, chronic diarrhea, pregnancy, lifting heavy weights, or straining when passing a stool.

Anal Fistula: It is an abnormal connection between the inside of the anal canal and the skin around the anus resulting from an injury or surgery. Infection or inflammation can also cause a fistula to form.