SR Pevesca Plus 150 mg Tablet is a combination of medicine that belongs to the class of medicines known as ‘anticonvulsant'. It is primarily used for the treatment of neuropathic pain. Neuropathic pain is a chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash) or spinal cord injury, injuries to tissue, muscles or joints.

SR Pevesca Plus 150 mg Tablet contains four medicines namely Pregabalin, Mecobalamin, Folic acid and Pyridoxine. Pregabalin works by calming the damaged or overactive nerves in your body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body. Mecobalamin and pyridoxine both are forms of vitamin B and helps in the reconstruction and protection of damaged nerve cells by producing a substance called myelin. A folic acid is also a form of vitamin B that helps in providing essential nutrients to the nerves. Together, SR Pevesca Plus 150 mg Tablet helps in providing relief from neuropathic (damage nerve) pain.

Take SR Pevesca Plus 150 mg Tablet as prescribed by your doctor. You are advised to take SR Pevesca Plus 150 mg Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dizziness, tiredness, sleepiness and uncoordinated body movements. Most of these side effects of SR Pevesca Plus 150 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking SR Pevesca Plus 150 mg Tablet for as long as your doctor has prescribed. Please do not stop taking SR Pevesca Plus 150 mg Tablet without consulting your doctor as it could cause withdrawal symptoms. SR Pevesca Plus 150 mg Tablet should not be given to children as safety and effectiveness have not been established. Do not take SR Pevesca Plus 150 mg Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. SR Pevesca Plus 150 mg Tablet causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with SR Pevesca Plus 150 mg Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

SR Pevesca Plus 150 mg Tablet is a combination of four medicines namely Pregabalin, Mecobalamin, Folic acid and Pyridoxine. Pregabalin is an anti-convulsant that affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels, this helps relieve nerve pain and lowers the risk of seizures. Mecobalamin and pyridoxine both are forms of vitamin B and helps in the reconstruction and protection of damaged nerve cells by producing a substance called myelin. Folic acid is a vitamin that helps in providing essential nutrients to the nerves. Together, SR Pevesca Plus 150 mg Tablet helps in providing relief from neuropathic pain.  Additionally, SR Pevesca Plus 150 mg Tablet may also be used to treat diabetic neuropathy, fibromyalgia (muscle pain) and postherpetic neuralgia (burning pain in nerves and skin).

• Dizziness

• Tiredness

• Sleepiness

• Nausea and vomiting

• Stomach discomfort and pain

• Uncoordinated body movements

• Swelling of face, lips, eyelids, tongue, hands and feet

• Blurred or double vision

• Unusual tiredness and weakness

• Dry mouth

• Fever

Do not take SR Pevesca Plus 150 mg Tablet if you are allergic to any of its contents. Inform your doctor before taking SR Pevesca Plus 150 mg Tablet if you have or had heart problems or bipolar syndrome. Please do not stop taking SR Pevesca Plus 150 mg Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take SR Pevesca Plus 150 mg Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. SR Pevesca Plus 150 mg Tablet causes drowsiness and dizziness, so drive only if you are alert. SR Pevesca Plus 150 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with SR Pevesca Plus 150 mg Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions: SR Pevesca Plus 150 mg Tablet may have interaction with other anti-convulsant medications (gabapentin, phenobarbital, phenytoin), antidepressant medications (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline), pain killer medications (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol), anti-anxiety medications (diazepam, alprazolam), anti-diabetic medications (metformin), immunosuppressant medications (methotrexate), anti-rheumatoid medications (sulfasalazine), antibiotic medications (neomycin, chloramphenicol), anti-cancer medications (altretamine), anti-Parkinson’s medications (levodopa).

Drug-Food Interactions: Avoid consumption of alcohol while taking SR Pevesca Plus 150 mg Tablet as it might cause increased dizziness and sleepiness.

Drug- Disease Interactions: SR Pevesca Plus 150 mg Tablet may have interactions with disease conditions such as suicidal tendency, heart problems, liver/kidney impairment angioedema, peripheral edema, malabsorption and anemia.

• GABAPENTIN
• PHENOBARBITAL
• PHENYTOIN
• AMITRIPTYLINE
• DULOXETINE
• MIRTAZAPINE
• FLUOXETINE
• SERTRALINE
• CODEINE
• FENTANYL
• HYDROCODONE
• MORPHINE
• OXYCODONE
• TRAMADOL
• DIAZEPAM
• ALPRAZOLAM
• METFORMIN
• METHOTREXATE
• SULFASALAZINE
• NEOMYCIN
• CHLORAMPHENICOL
• ALTRETAMINE
• LEVODOPA

• Include food rich in vitamin B and D in your diet.

• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

• Exercising regularly helps in improving overall health and combating pain.

• Rest well, get plenty of sleep.

• Try taking a warm bath as it can be soothing.

• Avoid smoking and alcohol consumption.

• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

• Acupuncture can be helpful by stimulating pressure points.

• Using essential oils for massages can help increase circulation.

• Consult your doctor immediately if you observe any changes in your behaviour, physically, mentally or psychologically.

•  You are recommended not to stop SR Pevesca Plus 150 mg Tablet suddenly, without consulting with your doctor.

• Inform your doctor about any addictions as SR Pevesca Plus 150 mg Tablet may cause dependence, especially in patients who are chronic alcohol users or in patients who have used other recreational drugs in the past. Report the past use of alcohol or other drugs to the doctor before receiving SR Pevesca Plus 150 mg Tablet .

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).