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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:52 AM IST

Spirodin-650 Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It contains Doxofylline, which relaxes the bronchial smooth muscle of the lung's airways, making it easier for asthma and COPD patients to breathe easily. It may cause side effects such as headaches, nausea, vomiting, stomach pain, irritability, insomnia (difficulty in falling or staying asleep) or a fast heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer

Koye Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Spirodin-650 Tablet

Spirodin-650 Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Spirodin-650 Tablet contains Doxofylline, which acts by inhibiting phosphodiesterase 4 (PD-4), thereby relaxing the bronchial smooth muscle of the lung's airways, making it easier for asthma and COPD patients to breathe easily.

Use Spirodin-650 Tablet as prescribed. Your doctor will recommend you how often you take Spirodin-650 Tablet based on your medical condition. Some people may experience headaches, nausea, vomiting, stomach pain, irritability, insomnia (difficulty in falling or staying asleep) or a fast heart rate. Most of these side effects of Spirodin-650 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Spirodin-650 Tablet is contraindicated in acute myocardial infarction, low blood pressure (hypotension), lactating women and patients allergic to Spirodin-650 Tablet . Let your doctor know if you are pregnant or planning for pregnancy, before using Spirodin-650 Tablet . Spirodin-650 Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance, leading to high blood levels even after stopping treatment with Spirodin-650 Tablet .

Uses of Spirodin-650 Tablet

Treatment of Asthma, Chronic obstructive pulmonary disease (COPD)

Medicinal Benefits

Spirodin-650 Tablet is a bronchodilator and also possesses antitussive (cough suppressant) properties that are used to treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Spirodin-650 Tablet works by relaxing muscles and widening the airways of the lungs, especially in asthma and COPD patients. Additionally, Spirodin-650 Tablet helps in suppressing cough and makes breathing easier by opening airways. Thus, it prevents an asthma attack, and an individual can exercise freely if it is taken before exercise or before expected exposure to irritants such as pollen, house dust, cigarette smoke and pets.

Directions for Use

Tablet/Capsule: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Syrup: Shake the bottle well before use. Check the label for directions and take it in doses as prescribed by your doctor with the help of a measuring cup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Spirodin-650 Tablet

  • Headache

  • Nausea

  • Vomiting

  • Stomach pain

  • Irritability

  • Insomnia (difficulty in falling or staying asleep)

  • Fast heart rate

Drug Warnings

If you are allergic to Spirodin-650 Tablet or any other medicines, please tell your doctor. You are recommended to avoid taking Spirodin-650 Tablet with chocolate and caffeinated foods such as cocoa beans or tea leaves as they may increase the risk of severity of side effects. Spirodin-650 Tablet is contraindicated in breastfeeding mothers. If you are pregnant or planning for pregnancy, please consult a doctor before using Spirodin-650 Tablet . Do not take Spirodin-650 Tablet if you have low blood pressure or had a heart attack. Spirodin-650 Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance leading to high blood levels even after stopping treatment with Spirodin-650 Tablet . If you have low blood pressure, congestive heart failure, hypoxemia (low oxygen levels in the blood), hyperthyroidism (overactive thyroid), pulmonary heart diseases, stomach ulcer, kidney, liver or heart diseases, inform your doctor before taking Spirodin-650 Tablet .

Drug Interactions

Drug-Drug Interaction: Spirodin-650 Tablet may interact with medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (erythromycin, clindamycin, lincomycin), drugs used to lower high blood pressure (propranolol), central nervous system stimulant (ephedrine), flu vaccine (influenza vaccine) and anticonvulsants (phenytoin),

Drug-Food Interaction: Spirodin-650 Tablet may interact with caffeine. Therefore, avoid intake of Spirodin-650 Tablet with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects.

Drug-Disease Interaction: If you have low blood pressure, congestive heart failure, hypoxemia (low oxygen levels in the blood), hyperthyroidism (overactive thyroid), pulmonary heart diseases, stomach ulcer, kidney, liver or heart diseases, inform your doctor before taking Spirodin-650 Tablet .

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • CIMETIDINE
  • ERYTHROMYCIN
  • CLINDAMYCIN
  • LINCOMYCIN
  • PROPRANOLOL
  • EPHEDRINE
  • INFLUENZA (LIVE ATTENUATED)
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.

  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.

  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen asthma symptoms.

  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.

  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

  • Quit smoking as it may reduce the effectiveness of the Spirodin-650 Tablet and irritate the lungs worsening breathing problem.

Special Advise

  • Regular blood tests are recommended while taking Spirodin-650 Tablet to monitor potassium levels and levels of Spirodin-650 Tablet in the blood.

  • Spirodin-650 Tablet can cause serious side effects, possibly similar, which occurs by taking too much amount of caffeine. So avoid intake of Spirodin-650 Tablet with caffeinated beverages like chocolate, coffee etc.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Caution

The interaction of Spirodin-650 Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol with Spirodin-650 Tablet .

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Pregnancy

Caution

The safety of Spirodin-650 Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Spirodin-650 Tablet is contraindicated in breastfeeding mothers. Please consult a doctor before taking Spirodin-650 Tablet if you are breastfeeding.

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Driving

Safe if prescribed

Spirodin-650 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Spirodin-650 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Spirodin-650 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Spirodin-650 Tablet is not recommended for children below 6 years of age, as the safety and effectiveness were not established. However, please consult a doctor before giving Spirodin-650 Tablet for children.

Country of origin

India

Manufacturer/Marketer address

A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070
Other Info - SPI0256

Author Details

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FAQs

Spirodin-650 Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD).
Spirodin-650 Tablet contains Doxofylline which belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Additionally, Spirodin-650 Tablet possess antitussive (cough suppressant) properties and helps in suppressing cough. Thereby, makes breathing easier by opening airways.
No, you are not recommended to take erythromycin with Spirodin-650 Tablet as co-administration of these medicines may increase the risk of adverse effects of Spirodin-650 Tablet . However, please consult a doctor before using other medicines with Spirodin-650 Tablet .
You are recommended to avoid taking Spirodin-650 Tablet if you are allergic to Spirodin-650 Tablet or other xanthine derivatives if you are breastfeeding, suffering from low blood pressure or had a heart attack. However, inform your doctor if you have any of these conditions before taking Spirodin-650 Tablet .
You are not recommended to take more than the prescribed dose of Spirodin-650 Tablet as it may cause overdose resulting in irregular heartbeats and fits. However, if you experience any of these symptoms while taking Spirodin-650 Tablet , please consult a doctor immediately.
No, you are not recommended to smoke while taking Spirodin-650 Tablet as it may reduce the effectiveness of Spirodin-650 Tablet .
No, you are not recommended to stop taking Spirodin-650 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Spirodin-650 Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Spirodin-650 Tablet , please consult your doctor.
No, Spirodin-650 Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
Even if you feel well, do not stop using Spirodin-650 Tablet as it might cause worsening symptoms. To treat your condition effectually, continue using Spirodin-650 Tablet for as long as your doctor has prescribed it.
Spirodin-650 Tablet is not recommended for children below 6 years of age, as the safety and effectiveness were not established. However, please consult a doctor before giving Spirodin-650 Tablet for children.
Spirodin-650 Tablet helps in suppressing cough and makes breathing easier by opening airways. Thus, it prevents an asthma attack.
No, It belongs to the class of bronchodilator (methylxanthine bronchodilator).
No, it belongs to the class of bronchodilators (methylxanthines bronchodilators).

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