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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sompraz D 40 Capsule is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It contains Esomeprazole and Domperidone, which blocks acid production and increases the movements and contractions of stomach muscles. Thus, helps in treating acidity-related problems. It may cause common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Sompraz D 40 Capsule

Sompraz D 40 Capsule belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Sompraz D 40 Capsule is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Sompraz D 40 Capsule helps in treating acidity-related problems.

You are advised to take Sompraz D 40 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Sompraz D 40 Capsule if you are pregnant or breastfeeding. Sompraz D 40 Capsule may cause dizziness, so drive only if you are alert. Sompraz D 40 Capsule should not be given to children as safety has not been established. Avoid consuming alcohol and Sompraz D 40 Capsule as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Sompraz D 40 Capsule

Treatment of Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and Stomach ulcers.

Directions for Use

Take Sompraz D 40 Capsule 1 hour prior to food. Swallow the medicine as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Sompraz D 40 Capsule is a combination of two drugs: Esomeprazole and Domperidone. Sompraz D 40 Capsule is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Sompraz D 40 Capsule helps in treating acidity-related problems.

How Sompraz D 40 Capsule Works

Sompraz D 40 Capsule is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Sompraz D 40 Capsule helps in treating acidity-related problems.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sompraz D 40 Capsule

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

What if I have taken an overdose of Sompraz D 40 Capsule

Do not take more than the prescribed dose of Sompraz D 40 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sompraz D 40 Capsule if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Sompraz D 40 Capsule if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Sompraz D 40 Capsule . On long-term treatment, Sompraz D 40 Capsule may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Sompraz D 40 Capsule may cause dizziness, so drive only if you are alert. Sompraz D 40 Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Sompraz D 40 Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Sompraz D 40 Capsule is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
DomperidoneBepridil
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Sompraz D 40 Capsule 15's:
Sompraz D 40 Capsule 15's may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Nefazodone can increase the blood levels of Sompraz D 40 Capsule 15's.

How to manage the interaction:
There may be a possibility of interaction between Sompraz D 40 Capsule 15's and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Sompraz D 40 Capsule 15's and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Combining Mizolastine with Sompraz D 40 Capsule 15's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Sompraz D 40 Capsule 15's and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with Sompraz D 40 Capsule 15's:
Coadministration of Sompraz D 40 Capsule 15's with Cisapride can increase the blood levels of Sompraz D 40 Capsule 15's.

How to manage the interaction:
There may be a possibility of interaction between Sompraz D 40 Capsule 15's and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Sompraz D 40 Capsule Substitute

Substitutes safety advice
  • Esomecare Dsr 40/30 Cap 10'S

    9.40per tablet
  • Nexpro RD 40 Capsule 10's

    16.70per tablet
  • Esogress-D Capsule 10's

    by AYUR

    12.69per tablet
  • Esomac D 40 Capsule 10's

    19.26per tablet
  • Raciper D Capsule 15's

    by AYUR

    15.90per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Sompraz D 40 Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Sompraz D 40 Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Sompraz D 40 Capsule ; your doctor will decide whether Sompraz D 40 Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Sompraz D 40 Capsule may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Sompraz D 40 Capsule if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Sompraz D 40 Capsule if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Sompraz D 40 Capsule should not be given to children as safety and effectiveness were not established.

FAQs

Sompraz D 40 Capsule is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers.
Sompraz D 40 Capsule contains Esomeprazole and Domperidone. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Sompraz D 40 Capsule helps in treating acidity.
Diarrhoea might be a side-effect of Sompraz D 40 Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.
Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.
Dry mouth could be a side-effect of Sompraz D 40 Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.
Sompraz D 40 Capsule contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscles.
Do not take Sompraz D 40 Capsule for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Sompraz D 40 Capsule for 14days.
Sompraz D 40 Capsule should not be taken along with HIV medicines such as atazanavir, ritonavir, nelfinavir, and saquinavir as Sompraz D 40 Capsule might affect their absorption. Consult your doctor before taking Sompraz D 40 Capsule with other medicines to avoid unpleasant side-effects.
On long-term treatment, Sompraz D 40 Capsule might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.
Sompraz D 40 Capsule belongs to a group of gastrointestinal agents. It contains Esomeprazole and Domperidone, which help treat acidity-related conditions.
Yes, it is safe to use Sompraz D 40 Capsule if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Take Sompraz D 40 Capsule on an empty stomach, 1 hour before meals.
Sompraz D 40 Capsule may cause abnormal heartbeat. Consult the doctor if you have symptoms of irregular heartbeat like fainting, dizziness, and palpitations.
Sompraz D 40 Capsule should not be used if you are allergic to any of its components or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems.
Dry mouth could be a side effect of Sompraz D 40 Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
Sompraz D 40 Capsule may cause dizziness. Do not drive or operate machinery unless you are alert.
Yes, inform the doctor if you are pregnant or breastfeeding before taking Sompraz D 40 Capsule . The doctor will prescribe Sompraz D 40 Capsule if the benefits outweigh the risks.
If you miss a dose of Sompraz D 40 Capsule take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Avoid consumption of alcohol while taking Sompraz D 40 Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Store Sompraz D 40 Capsule at room temperature (not exceeding 30°C) protected from light and moisture. Keep out of reach of children.
Side effects of Sompraz D 40 Capsule include dry mouth, stomach pain, diarrhoea, headache, and flatulence. Talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001.
Other Info - SOM0109

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