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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Solu-Medrol 1 gm Injection 8 ml is used to treat symptoms associated with allergic reactions or inflammatory conditions. This medicine contains methylprednisolone, a corticosteroid that works by inhibiting the production of certain chemical messengers that cause inflammation. Thus, helps reduce swelling, redness, and itching. Let your doctor informed about your complete medical and medication history.
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Synonym :

METHYLPREDNISOLONE SODIUM SUCCINATE

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Solu-Medrol 1 gm Injection 8 ml

Solu-Medrol 1 gm Injection 8 ml belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. Solu-Medrol 1 gm Injection 8 ml is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons. It is also useful in treating severe allergic reactions, asthma, ulcerative colitis, and Crohn's disease (inflammatory bowel disease).

Solu-Medrol 1 gm Injection 8 ml contains methylprednisolone, a corticosteroid medicine. It works by suppressing the migration of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Solu-Medrol 1 gm Injection 8 ml is administered by a doctor in a hospital setting. Do not self-administer. It shows side effects like depression, suicidal thoughts, anxiety, sleeping disorders, difficulty in thinking or being confused, memory loss, hallucinations (seeing or hearing things that do not exist), and feeling high (mania) or mood swings. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects are persistent, consult your doctor.

Inform your doctor before receiving Solu-Medrol 1 gm Injection 8 ml if you are allergic to corticosteroids or methylprednisolone, if you just had a vaccination or have a vaccination planned, or if you have a viral infection such as measles or chickenpox, shingles, or any other medical condition. Stay away from people who have chickenpox or shingles. Consult your doctor immediately if you come into contact with chickenpox or shingles patients. If you are pregnant or breastfeeding and suspect pregnancy or planning pregnancy, inform your doctor before receiving this medicine. Solu-Medrol 1 gm Injection 8 ml is generally not recommended for use in children as it may delay growth and development and cause severe headaches with blurred vision or temporary visual problems in children. Your paediatrician may weigh the benefits and risks before prescribing this medicine to your child.

Uses of Solu-Medrol 1 gm Injection 8 ml

Treatment of Allergic and inflammatory conditions

Directions for Use

Solu-Medrol 1 gm Injection 8 ml is administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Solu-Medrol 1 gm Injection 8 ml plays a vital role in treating a wide range of allergic reactions and inflammation in the body by blocking certain chemical messengers known as 'histamine,' which is naturally involved in allergic reactions. Solu-Medrol 1 gm Injection 8 ml is accepted to treat various medical conditions such as allergies, joint inflammation (arthritis, golfer's elbow), breathing problems (e.g., asthma), and intestinal problems (e.g., ulcerative colitis, inflammatory bowel disease). Take this medicine for the duration prescribed by your doctor for its maximum benefits.

How Solu-Medrol 1 gm Injection 8 ml Works

Solu-Medrol 1 gm Injection 8 ml contains methylprednisolone, a corticosteroid medicine. It works by suppressing the migration of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergies and inflammation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Solu-Medrol 1 gm Injection 8 ml

  • Feeling depressed

  • Suicidal thoughts

  • Feeling anxious

  • Sleeping disorders

  • Being confused or having difficulty in thinking

  • Memory loss

  • Hallucinations (feeling, seeing or hearing things which do not exist)

  • Feeling high (mania) or mood swings

  • Having strange and frightening thoughts

  • Changing how you act behavioural changes

  • Loneliness and isolation (having feelings of being alone)

What if I have taken an overdose of Solu-Medrol 1 gm Injection 8 ml

Solu-Medrol 1 gm Injection 8 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of this medicine may cause elevated blood pressure, retention of salt and water can result in swelling in your feet, legs, or arms, low blood potassium levels, which can lead to fatigue, cramping in the muscles, and weakness. Your doctor may take immediate necessary measures if an overdose is suspected.

Drug Warnings

Inform your doctor if you are allergic to steroids, methylprednisolone, or any components present in the Solu-Medrol 1 gm Injection 8 ml. Inform your doctor if you are pregnant or breastfeeding before receiving Solu-Medrol 1 gm Injection 8 ml. Your doctor will weigh the benefits and potential risks before prescribing Solu-Medrol 1 gm Injection 8 ml for you. Let your doctor know if you have bipolar disorder or depression, tuberculosis, diabetes, epilepsy, glaucoma, osteoporosis, myasthenia gravis (muscle weakness), stomach ulcers, high blood pressure or heart failure, liver or kidney problems or any viral infections or if you are about to undergo an organ transplantation procedure. Solu-Medrol 1 gm Injection 8 ml is generally not recommended for use in children because it can cause growth and development delays as well as severe headaches with blurred vision or temporary visual problems. Individuals with poor immune systems should not take any live vaccinations while taking this medicine. It is safe to take killed vaccinations or toxoids (inactivated toxins), as their effects may be limited.

Drug-Drug Interactions

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MethylprednisoloneIohexol
Critical
MethylprednisoloneMifepristone
Critical

Drug-Drug Interactions

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MethylprednisoloneIohexol
Critical
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Solu-Medrol 1 gm Injection 8 ml with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneMifepristone
Critical
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
When Solu-Medrol 1 gm Injection 8 ml is taken with Mifepristone, it may decrease the levels of Solu-Medrol 1 gm Injection 8 ml, which may be less effective in treating your condition.

How to manage the interaction:
Taking Solu-Medrol 1 gm Injection 8 ml with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneVigabatrin
Critical
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Co-administration of Solu-Medrol 1 gm Injection 8 ml and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Solu-Medrol 1 gm Injection 8 ml with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneLeflunomide
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Using leflunomide together with Solu-Medrol 1 gm Injection 8 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction between leflunomide and Solu-Medrol 1 gm Injection 8 ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
MethylprednisolonePosaconazole
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Coadministration of posaconazole with Solu-Medrol 1 gm Injection 8 ml may significantly increase the blood levels of Solu-Medrol 1 gm Injection 8 ml, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Solu-Medrol 1 gm Injection 8 ml, it can be taken if a doctor has advised it. However, if you experience swelling, weight gain, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneAtazanavir
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Coadministration of Solu-Medrol 1 gm Injection 8 ml with Atazanavir may significantly increase the blood levels of Solu-Medrol 1 gm Injection 8 ml.

How to manage the interaction:
Although taking Solu-Medrol 1 gm Injection 8 ml and Atazanavir together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thin skin, easy bruising, irregular periods, bruises, too much facial or body hair, strange fat distribution, infection, or a bad asthma attack - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneCertolizumab
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Using Solu-Medrol 1 gm Injection 8 ml together with certolizumab may increase the risk of serious infections.

How to manage the interaction:
Although taking Solu-Medrol 1 gm Injection 8 ml and Certolizumab together can cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: a bad infection, sepsis, problems, fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, losing weight, or pain or burning when you pee. Do not discontinue any medications without consulting a doctor.
MethylprednisoloneEtanercept
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
The use of Etanercept with Solu-Medrol 1 gm Injection 8 ml can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Solu-Medrol 1 gm Injection 8 ml, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
MethylprednisoloneClarithromycin
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Taking Clarithromycin with Solu-Medrol 1 gm Injection 8 ml together may significantly increase the blood levels of Solu-Medrol 1 gm Injection 8 ml.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Solu-Medrol 1 gm Injection 8 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, eye problems, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not discontinue any medications without a doctor's advice.
MethylprednisoloneAdalimumab
Severe
How does the drug interact with Solu-Medrol 1 gm Injection 8 ml:
Using adalimumab together with Solu-Medrol 1 gm Injection 8 ml may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Solu-Medrol 1 gm Injection 8 ml and Adalimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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METHYLPREDNISOLONE-1000MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLPREDNISOLONE-1000MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Solu-Medrol 1 gm Injection 8 ml with Grapefruit may increase the blood level of Solu-Medrol 1 gm Injection 8 ml. Avoid consuming Grapefruit and Grapefruit juice while taking Solu-Medrol 1 gm Injection 8 ml.

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, tomatoes, cherries, squash, and bell peppers are high in antioxidants.
  • Consuming probiotic-rich foods aids in the development of the immune system's resistance to allergies.
  • Consume foods that are rich in quercetin (a flavonoid), such as apples, cherries, spinach, broccoli, and blueberries.
  • Include seasonal fruits, vegetables, whole grains, healthy fats, and fish in your daily diet.
  • Limit your intake of foods that may cause allergies, such as dairy products, soy, eggs, and nuts.
  • Limit the consumption of foods high in sugar that may aggravate inflammation.
  • Reducing stress and having a regular sleep schedule might be beneficial.
  • Avoid processed meats, refined carbohydrates, sugar, trans fats, and alcohol, as they may aggravate inflammation.

Habit Forming

No

Therapeutic Class

CORTICOSTEROIDS

Solu-Medrol 1 gm Injection 8 ml Substitute

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Alcohol

Caution

No interaction was found. However, limit alcohol consumption as a precautionary measure.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect or planning pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Solu-Medrol 1 gm Injection 8 ml.

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Breast Feeding

Safe if prescribed

Solu-Medrol 1 gm Injection 8 ml is considered safe to be used during breastfeeding. If you are breastfeeding, inform your doctor before receiving this injection. Your doctor will weigh the benefits and potential risks before prescribing Solu-Medrol 1 gm Injection 8 ml.

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Driving

Caution

Solu-Medrol 1 gm Injection 8 ml has no or insignificant effect on one's ability to drive or operate machinery. In rare cases, Solu-Medrol 1 gm Injection 8 ml may cause blurred vision or other visual disturbances. If you experience these symptoms, do not drive or operate machinery until you are alert.

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Liver

Caution

If you have a history of liver diseases/conditions or ongoing liver conditions, inform your doctor before receiving Solu-Medrol 1 gm Injection 8 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

If you have a history of kidney diseases/conditions or ongoing kidney conditions, inform your doctor before receiving Solu-Medrol 1 gm Injection 8 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Solu-Medrol 1 gm Injection 8 ml is generally not recommended for use in children because it can delay growth and development as well as severe headaches with blurred vision or temporary visual problems. Before prescribing this medication to your child, your paediatrician may weigh the benefits and risks.

FAQs

Solu-Medrol 1 gm Injection 8 ml belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. It is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons.
Solu-Medrol 1 gm Injection 8 ml contains the corticosteroid medication methylprednisolone. It works by blocking the transmission of certain chemical messengers in the body that cause inflammation and allergic reactions, effectively treating a variety of medical conditions associated with allergic and inflammatory reactions.
Corticosteroid medications such as Solu-Medrol 1 gm Injection 8 ml can alter how your body processes carbs and sugars (glucose). They can elevate your blood sugar by preventing insulin from working. If you have diabetes, your blood glucose levels need to be monitored regularly while you are on treatment with this medicine.
Solu-Medrol 1 gm Injection 8 ml is not recommended for treating viral infections such as measles, chickenpox, shingles, or any other viral conditions.
Complete the entire course of treatment with Solu-Medrol 1 gm Injection 8 ml even if you feel better after receiving a few doses, as abrupt stopping may lead to undesirable effects.
While taking Solu-Medrol 1 gm Injection 8 ml, do not receive a "live" vaccine (including measles, mumps, polio, chickenpox) as the vaccine may not work, and you may develop the disease again.

Country of origin

United States

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - SOL0007

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