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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 13, 2024 | 11:26 AM IST
SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). It contains isoniazid, which prevents bacteria from producing mycolic acid, an enzyme required for cell wall formation (protective coating). Thus, kills bacteria and inhibits the spread of infection. It may cause side effects such as fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

ISONIAZID-100MG

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET belongs to a group of medicines called anti-tubercular agents, which are primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. SOLONEX DT 100MG TABLET does not work against infections caused by the virus.

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic that prevents bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, SOLONEX DT 100MG TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take SOLONEX DT 100MG TABLET as prescribed. Use SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of SOLONEX DT 100MG TABLET. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to SOLONEX DT 100MG TABLET or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET.  Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while on treatment with SOLONEX DT 100MG TABLET as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Uses of SOLONEX DT 100MG TABLET

Treatment of Tuberculosis (TB).

Medicinal Benefits

SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required to form cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Directions for Use

Take SOLONEX DT 100MG TABLET on an empty stomach at least one hour before or two hours after a meal or as your doctor advises. Do not take it with food. Tablet: Swallow it whole with a glass of water. Do not crush, break, or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SOLONEX DT 100MG TABLET

  • Fever
  • Dizziness
  • Nausea
  • Stomach upset
  • Loss of appetite
  • Constipation
  • Tiredness
  • Numbness or tingling in the feet or hands

Drug Warnings

If you are known to be allergic to SOLONEX DT 100MG TABLET, please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking SOLONEX DT 100MG TABLET. SOLONEX DT 100MG TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET. Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking SOLONEX DT 100MG TABLET as they might cause drug-food interaction. Avoid alcohol consumption with SOLONEX DT 100MG TABLET as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Drug Interactions

Drug-Drug Interaction: SOLONEX DT 100MG TABLET may have interaction with anticonvulsants (carbamazepine, phenobarbital, valproic acid, phenytoin), medicines that help to sleep (flurazepam, midazolam, diazepam, triazolam), antipsychotics (haloperidol, chlorpromazine), medicines used to prevent blood clots (warfarin, phenindione), bronchodilator (theophylline), anti-arrhythmic drug (procainamide), antifungal (ketoconazole), corticosteroids (prednisolone), painkiller (paracetamol), opioids (alfentanil) and anaesthetic (enflurane). 

Drug- Food Interaction: Avoid alcohol consumption with SOLONEX DT 100MG TABLET as it may increase the risk of liver damage. Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking SOLONEX DT 100MG TABLET as they might cause interaction.

Drug-Disease Interaction: If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking SOLONEX DT 100MG TABLET.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking SOLONEX DT 100MG TABLET to monitor your liver function.

  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.

  • A monthly liver function test is advisable while using SOLONEX DT 100MG TABLET.

 

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a tuberculosis patient. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with SOLONEX DT 100MG TABLET as it may increase the risk of liver damage. Please consult your doctor in case of any concerns.

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Pregnancy

Safe if prescribed

If you are pregnant, consult your doctor before taking SOLONEX DT 100MG TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Breast Feeding

Safe if prescribed

SOLONEX DT 100MG TABLET is excreted in breast milk in low quantities. If you are breastfeeding, consult your doctor before taking SOLONEX DT 100MG TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Driving

Unsafe

SOLONEX DT 100MG TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking SOLONEX DT 100MG TABLET.

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Liver

Caution

Take SOLONEX DT 100MG TABLET with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Take SOLONEX DT 100MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Caution

SOLONEX DT 100MG TABLET is not recommended for children below 3 months of age. However, in children above 3 months, SOLONEX DT 100MG TABLET should be used under medical supervision.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - SOL0027

Author Details

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FAQs

SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB).
SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required to form cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die due to the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.
It is not recommended to take SOLONEX DT 100MG TABLET with food. You are advised to take SOLONEX DT 100MG TABLET on an empty stomach at least 1 hour before a meal or 2 hours after a meal for better absorption.
You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer as they may interact with SOLONEX DT 100MG TABLET and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.
Yes, SOLONEX DT 100MG TABLET may cause liver problems in some patients. However, please consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may monitor your liver function while on treatment with SOLONEX DT 100MG TABLET.
You are advised to consult a doctor before taking phenytoin with SOLONEX DT 100MG TABLET as taking these medicines together may increase the levels of phenytoin in the blood and cause toxic effects. However, if you experience dizziness, vomiting, confusion or nausea, please consult your doctor.
Please do not stop taking SOLONEX DT 100MG TABLET suddenly without consulting your doctor as it may cause withdrawal symptoms such as irritation, nervousness, difficulty in sleeping, headache or having more dreams. Therefore, take SOLONEX DT 100MG TABLET for as long as your doctor has prescribed it, and if you experience any difficulty while taking SOLONEX DT 100MG TABLET, please consult your doctor.
SOLONEX DT 100MG TABLET is not recommended for patients suffering from fits as it may increase the risk of recurring fits. Therefore, it is advised to inform your doctor if you have a history of fits before taking SOLONEX DT 100MG TABLET.
Inform your doctor if your symptoms are not relieved after completing the full course of SOLONEX DT 100MG TABLET. If you notice any undesirable effects that bother you while taking SOLONEX DT 100MG TABLET, consult your doctor.
If you miss taking a dose SOLONEX DT 100MG TABLET, then take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking more to make up for the missed one.
You are not recommended to stop taking SOLONEX DT 100MG TABLET even if you feel better, as you may experience unwanted side effects. Take SOLONEX DT 100MG TABLET as long as advised by a doctor for the effective response. However, contact a doctor if you have any concerns.
SOLONEX DT 100MG TABLET causes side effects such as fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, and numbness in feet or hands. Most of these are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.

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