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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:39 PM IST
Skizofinale-200 Tablet is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. It contains Clozapine, which helps in improving mood, behaviour and thoughts. It may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

CLOZAPINE-200MG

Manufacturer/Marketer

Myk Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Skizofinale-200 Tablet

Skizofinale-200 Tablet is used to treat schizophrenia. Additionally, Skizofinale-200 Tablet is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Schizophrenia is a medical condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Skizofinale-200 Tablet contains ‘Clozapine’, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour and thoughts.

You are advised to take Skizofinale-200 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Skizofinale-200 Tablet may cause side effects such as tachycardia (fast heartbeat), dizziness, headache, tremor, sweating, dry mouth, nausea, constipation and visual disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Skizofinale-200 Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor if you are pregnant. Do not take Skizofinale-200 Tablet if you are breastfeeding, as it may pass into breastmilk. Avoid driving as Skizofinale-200 Tablet may cause drowsiness and dizziness. Skizofinale-200 Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Skizofinale-200 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Skizofinale-200 Tablet

Treatment of Schizophrenia

Medicinal Benefits

Skizofinale-200 Tablet belongs to a group of medicines called antipsychotics. Skizofinale-200 Tablet is used to treat schizophrenia and to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Skizofinale-200 Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby helping in improving mood, behaviour and thoughts. Skizofinale-200 Tablet is used to treat schizophrenia when other antipsychotic drugs are ineffective or have caused severe adverse effects. Skizofinale-200 Tablet is also used to treat psychotic disorders in patients with Parkinson’s disease when standard treatments have failed.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush it.Orodispersible/Mouth dissolving tablet: Check the label for directions before use. Place the tablet in the mouth and allow it to dissolve.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Skizofinale-200 Tablet

  • Tachycardia (fast heartbeat)
  • Dizziness
  • Headache
  • Tremor
  • Sweating
  • Low blood pressure
  • Dry mouth
  • Nausea
  • Constipation
  • Visual disturbances

Drug Warnings

Do not take Skizofinale-200 Tablet if you are allergic to any of its contents if you have galactose intolerance, total lactase deficiency, glucose-galactose malabsorption, low number of white blood cells or if you are taking medicines that can cause low levels of white blood cells, bone marrow disorder, epilepsy, circulatory collapse (pronounced fall in blood pressure that can lead to unconsciousness), brain disorders, severe kidney disease, heart disease, liver disease with jaundice, liver failure or paralytic ileus (small intestine disorder). Inform your doctor if you have a low number of white blood cells or platelet count, orthostatic hypotension, epilepsy, enlarged prostate or difficulty urinating, glaucoma, severe constipation, diabetes, heart, liver or kidney problems. Consult your doctor if you are pregnant. Do not take Skizofinale-200 Tablet if you are breastfeeding, as it may pass into breastmilk.

Drug Interactions

Drug-Drug Interactions: Skizofinale-200 Tablet may interact with antipsychotic (aripiprazole, haloperidol, lurasidone, lithium, risperidone, quetiapine, olanzapine), anti-anxiety (lorazepam, alprazolam), anti-cholinergic (benztropine), anti-depressant (duloxetine, escitalopram, sertraline), anti-convulsant (divalproex sodium, clonazepam, lamotrigine),  muscle relaxants (carisoprodol, cyclobenzaprine),  antihistamines (cetirizine, diphenhydramine).

Drug-Food Interactions: Avoid consuming alcohol as it could lead to increased dizziness.

Drug-Disease Interactions: Inform your doctor if you have dementia (memory loss), CNS depression, liver disease, seizures, low blood pressure, diabetes, lipid alterations, weight gain, parkinsonism, acute alcohol intoxication, neuroleptic malignant syndrome (occurs due to reaction with antipsychotic drugs), tardive dyskinesia (repetitive, involuntary movements), QT interval prolongation, kidney impairment/disease, blood abnormalities, or hyperprolactinemia (higher levels of prolactin in the blood).

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • HALOPERIDOL
  • LURASIDONE
  • LITHIUM
  • LORAZEPAM
  • ALPRAZOLAM
  • BENZTROPINE MESYLATE
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • DIVALPROEX SODIUM
  • CLONAZEPAM
  • LAMOTRIGINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include fruits, vegetables, and fibre-rich food in your diet.
  • Cut down on sugars, salts and saturated fats.
  • Drink enough fluids to stay hydrated.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Regular monitoring of blood count is advised as Skizofinale-200 Tablet may cause agranulocytosis (low white blood cells).

  • Skizofinale-200 Tablet may cause blood lipids (fats) alteration, which could lead to weight gain. Your doctor might monitor your weight and blood lipid levels regularly.

  • If you have a liver disorder, regular liver function tests are recommended for as long as Skizofinale-200 Tablet has been prescribed.

  • Skizofinale-200 Tablet might cause thrombosis (blood clotting in the vein). If you are due to have any surgery, inform your doctor that you are taking Skizofinale-200 Tablet .

  • Skizofinale-200 Tablet might affect how your body controls temperature; therefore, be cautious while exercising, taking hot baths or sauna.

Disease/Condition Glossary

Schizophrenia: It is a severe mental illness in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Schizophrenia is a long-term disease that affects brain functioning. People with schizophrenia may seem like they have lost touch with reality, which might cause significant distress for the individual, their friends and family. The exact cause is unknown; however, conditions like genetics, environment, brain structure and function could be the risk factors. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Skizofinale-200 Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Skizofinale-200 Tablet belongs to pregnancy category B. Please consult your doctor if you are pregnant before taking this medicine; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Skizofinale-200 Tablet is not recommended for use during breastfeeding.

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Driving

Unsafe

Skizofinale-200 Tablet causes tiredness, dizziness and vision problems. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Skizofinale-200 Tablet should not be given to children as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

100 Southview Cres Suite 1708 Winnipeg, Mb, R3Y 0W1 Canada.
Other Info - SKI0295

Author Details

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FAQs

Skizofinale-200 Tablet is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders.
Skizofinale-200 Tablet works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby improving mood, behaviour and thoughts.
Do not discontinue Skizofinale-200 Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Skizofinale-200 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Skizofinale-200 Tablet .
Skizofinale-200 Tablet may cause agranulocytosis (low levels of white blood cells), making you more prone to infections. Consult your doctor immediately if you experience flu-like symptoms, sore throat or fever.
Dry mouth could be a side-effect of Skizofinale-200 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Orthostatic hypotension could be a side-effect of Skizofinale-200 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.
Skizofinale-200 Tablet may cause tachycardia (fast heartbeat). Talk to your doctor if you experience irregular or fast heartbeat even at rest, chest pain, unexplained tiredness or breathing problems.
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take your regular dose. Please don't take a double dose to make up for a missed one.

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