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  3. Sizosure 80 Tablet 10's

Sizosure 80 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sizosure 80 Tablet 10's is used to treat schizophrenia and bipolar disorder. It contains Lurasidone which works by blocking neurotransmitters and helps regulate mood, thoughts and behaviour. In some cases, this medicine may cause side effects such as nausea, vomiting, sleepiness, weight gain, indigestion, dry mouth, and restlessness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

LURASIDONE HYDROCHLORIDE

Composition :

LURASIDONE-80MG

Manufacturer/Marketer :

Ikon Pharmachem

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sizosure 80 Tablet 10's

Sizosure 80 Tablet 10's used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Bipolar disorder is characterized by manic episodes in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

Sizosure 80 Tablet 10's contains ‘lurasidone’, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Sizosure 80 Tablet 10's also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, Sizosure 80 Tablet 10's helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Take Sizosure 80 Tablet 10's as prescribed by your doctor. You are advised to take Sizosure 80 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, vomiting, sleepiness, weight gain, indigestion, dryness in the mouth, akathisia (inability to stay still), stomach discomfort, anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), insomnia (difficulty in sleeping) and increased saliva production. Most of these side effects of Sizosure 80 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Sizosure 80 Tablet 10's should not be taken in conditions like if you are allergic to lurasidone or any other ingredients present in it. Before taking Sizosure 80 Tablet 10's, inform your doctor if you have problems associated with the liver, kidney or heart and low blood pressure. It is not recommended for use in children under 13 years of age. Before taking Sizosure 80 Tablet 10's inform your doctor if you are older than 65 years of age as it causes more side effects. Tell your doctor if you are pregnant or breastfeeding. Sizosure 80 Tablet 10's causes drowsiness and dizziness. Do not drive unless you are alert.

Uses of Sizosure 80 Tablet 10's

Treatment of Schizophrenia, Bipolar disorder

Directions for Use

Take Sizosure 80 Tablet 10's with or without food. Sizosure 80 Tablet 10's should be swallowed as a whole with a glass of water; do not chew or crush the tablet. You are advised to take Sizosure 80 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition.

Medicinal Benefits

Sizosure 80 Tablet 10's is used to treat certain mood /mental diseases like schizophrenia and depression related to bipolar disorder. Sizosure 80 Tablet 10's helps you to feel less nervous, think more clearly and take part in daily life. It may also help to reduce hallucinations (seeing/hearing things that are not there). It alters brain function and improves mood, thinking ability, and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. 

How Sizosure 80 Tablet 10's Works

Sizosure 80 Tablet 10's contains lurasidone, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Sizosure 80 Tablet 10's also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, Sizosure 80 Tablet 10's helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sizosure 80 Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.

What if I have taken an overdose of Sizosure 80 Tablet 10's

Take Sizosure 80 Tablet 10's only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is advisable to you not take Sizosure 80 Tablet 10's if you are allergic to lurasidone or any ingredients present in it. Before taking Sizosure 80 Tablet 10's, inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Inform your doctor if you have epilepsy/fits, an increase in your weight, history of blood clots before taking Sizosure 80 Tablet 10's. Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking Sizosure 80 Tablet 10's. There is a greater chance of death in senior adults who take Sizosure 80 Tablet 10's for mental problems caused by dementia (thinking and suicidal symptoms). Most of the deaths were related to infection or heart disease. Avoid drinking alcohol while taking Sizosure 80 Tablet 10's as it may worsen the side effects. Tell your doctor if you are pregnant or breastfeeding. Sizosure 80 Tablet 10's causes drowsiness and dizziness. Do not drive unless you are alert.

Drug-Drug Interactions

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LurasidonePosaconazole
Critical
LurasidonePhenytoin
Critical

Drug-Drug Interactions

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LurasidonePosaconazole
Critical
How does the drug interact with Sizosure 80 Tablet:
Taking Sizosure 80 Tablet together with posaconazole may result in significantly higher Sizosure 80 Tablet blood levels.

How to manage the interaction:
Although there is an interaction between Sizosure 80 Tablet and posaconazole, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, dizziness, lightheadedness, headache, flushing, or fainting. Do not discontinue any medications without consulting a doctor.
LurasidonePhenytoin
Critical
How does the drug interact with Sizosure 80 Tablet:
Using Sizosure 80 Tablet together with phenytoin may significantly decrease the blood levels of Sizosure 80 Tablet.

How to manage the interaction:
Using Sizosure 80 Tablet with phenytoin is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidoneKetoconazole
Critical
How does the drug interact with Sizosure 80 Tablet:
Using Sizosure 80 Tablet together with ketoconazole may increase the risk of side effects like Parkinson's disease(It is a brain disorder that produces uncontrollable movements).

How to manage the interaction:
While Sizosure 80 Tablet and ketoconazole is not recommended as it may lead to an interaction, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, fits, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneMifepristone
Critical
How does the drug interact with Sizosure 80 Tablet:
Coadministration of Sizosure 80 Tablet with Mifepristone can increase the levels of Sizosure 80 Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Sizosure 80 Tablet with Mifepristone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures(fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LurasidoneRifabutin
Critical
How does the drug interact with Sizosure 80 Tablet:
Sizosure 80 Tablet administration with Rifabutin may result in significantly lower blood levels of Sizosure 80 Tablet.

How to manage the interaction:
There is an interaction between Sizosure 80 Tablet and Rifabutin, so it is not recommended that you take it unless a doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidoneBoceprevir
Critical
How does the drug interact with Sizosure 80 Tablet:
Using Sizosure 80 Tablet together with Boceprevir may result in significantly higher Sizosure 80 Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Sizosure 80 Tablet and Boceprevir may interact,so it is not recommended, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor. Do not stop using any medications without first talking to your doctor.
LurasidoneFosphenytoin
Critical
How does the drug interact with Sizosure 80 Tablet:
Sizosure 80 Tablet co-administration with Fosphenytoin may result in significantly lower blood levels of Sizosure 80 Tablet, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
Although there is an interaction between Sizosure 80 Tablet and Fosphenytoin, you can take it if your doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidonePrimidone
Critical
How does the drug interact with Sizosure 80 Tablet:
Co-administration of Sizosure 80 Tablet with primidone may result in significantly lower blood levels of Sizosure 80 Tablet, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
There is an interaction between Sizosure 80 Tablet and Primidone, so it is not recommended; it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LurasidoneClarithromycin
Critical
How does the drug interact with Sizosure 80 Tablet:
Using Sizosure 80 Tablet together with Clarithromycin may result in significantly higher Sizosure 80 Tablet blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Sizosure 80 Tablet and Clarithromycin may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneVoriconazole
Critical
How does the drug interact with Sizosure 80 Tablet:
Using Sizosure 80 Tablet together with Voriconazole may result in significantly higher Sizosure 80 Tablet blood levels.

How to manage the interaction:
While Sizosure 80 Tablet and Voriconazole may interact, it is not recommended that they be used unless prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, dizziness, headache, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LURASIDONE-80MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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LURASIDONE-80MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking grapefruit juice with Sizosure 80 Tablet treatment can increase the levels of Sizosure 80 Tablet which can increase the risk or severity of side effects. Taking grapefruit juice with Sizosure 80 Tablet should be avoided as it can result in an interaction. Contact a doctor immediately if you experience symptoms like abnormal muscle movements, seizures, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations. Do not stop using any medications without talking to a doctor.

Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using Sizosure 80 Tablet 10's as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Sizosure 80 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while on treatment with Sizosure 80 Tablet 10's as it may increase the risk of side effects.

bannner image

Pregnancy

Caution

Sizosure 80 Tablet 10's is not recommended for use in pregnancy. Hence, if you are pregnant, inform your doctor before taking Sizosure 80 Tablet 10's. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is not known if Sizosure 80 Tablet 10's passes into the breastmilk. If you are breastfeeding, consult your doctor before taking Sizosure 80 Tablet 10's, your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Sizosure 80 Tablet 10's may cause dizziness. So, it is not recommended to drive or operate heavy machinery after taking Sizosure 80 Tablet 10's.

bannner image

Liver

Caution

Sizosure 80 Tablet 10's should be used with caution in patients with liver disease. If you have liver disease, inform your doctor before taking Sizosure 80 Tablet 10's. Your doctor may adjust the dose based on your condition.

bannner image

Kidney

Caution

Sizosure 80 Tablet 10's should be used with caution in patients with kidney disease. If you have kidney disease, inform your doctor before taking Sizosure 80 Tablet 10's. Your doctor may adjust the dose based on your condition.

bannner image

Children

Unsafe

Sizosure 80 Tablet 10's is not recommended for use in children under 13 years.

Have a query?

FAQs

Sizosure 80 Tablet 10's is used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). It helps you to feel less nervous, think more clearly and take part in daily life.

Sizosure 80 Tablet 10's may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Sizosure 80 Tablet 10's. Diabetes patients should consult a doctor before taking Sizosure 80 Tablet 10's.

Weight gain is a common side effect of Sizosure 80 Tablet 10's, although not everyone is affected. If you experience weight gain on taking Sizosure 80 Tablet 10's, inform your doctor. Eating a healthy diet and frequent exercise can help you maintain your weight.

Alcohol should be avoided while taking Sizosure 80 Tablet 10's since taking both together may lead to severe side effects. You should not drink grapefruit juice while on Sizosure 80 Tablet 10's as it affects the way it works.

Sizosure 80 Tablet 10's may raise the risk of death in older persons who suffer from memory loss, perplexity, or have lost touch with reality. It is critical to understand that Sizosure 80 Tablet 10's may cause suicidal behaviour or thoughts in certain children, adolescents, and young adults during the first few months of treatment and when the dose is adjusted.

Dry mouth could be a side-effect of Sizosure 80 Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Sizosure 80 Tablet 10's is an antipsychotic drug that works by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia (a serious mental illness affecting thoughts, feelings, and behaviours) and bipolar disorder (a mental illness that causes mood swings, energy fluctuations, and concentration issues). It also blocks other neurotransmitters in the brain, such as serotonin. By blocking both dopamine and serotonin, Sizosure 80 Tablet 10's helps to control brain activity and decreasesthe symptoms of schizophrenia and bipolar disorder.

The common side effects of Sizosure 80 Tablet 10's include nausea, vomiting, weight gain, indigestion, sleepiness, dryness in the mouth, increased saliva production, akathisia (inability to stay still), anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), and insomnia (difficulty in sleeping). Most of these side effects of Sizosure 80 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

No, Sizosure 80 Tablet 10's should not be used during pregnancy unless prescribed by the doctor. Taking Sizosure 80 Tablet 10's in the later months of pregnancy may lead to extrapyramidal (uncontrolled body movements or muscle stiffness in the baby) or withdrawal symptoms after birth such as muscle stiffness, weakness, shakiness, sleepiness, breathing problems, agitation, and difficulty feeding. If you are pregnant or planning for pregnancy, please consult your doctor before taking Sizosure 80 Tablet 10's. The doctor will prescribe Sizosure 80 Tablet 10's only if the benefits outweigh the risks and will monitor the baby closely after birth.

Close monitoring for the emergence or worsening of suicidal behaviour and thoughts is recommended in patients taking Sizosure 80 Tablet 10's. Sizosure 80 Tablet 10's may increase blood sugar levels in diabetic patients, especially in those with schizophrenia. So, you should immediately inform your doctor if you experience symptoms such as increased thirst, frequent urination, fatigue, or increased appetite. It may also lead to weight gain, increase prolactin, cholesterol, and triglyceride levels, and decrease white blood cell count. Hence, regular monitoring of blood sugar levels, blood cell counts, hormone levels (prolactin), and cholesterol levels is advised while taking Sizosure 80 Tablet 10's. 

Sizosure 80 Tablet 10's should be taken with food for better absorption of the medicine. It should be swallowed whole with a glass of water; do not chew or crush the tablet.

Sizosure 80 Tablet 10's may take several weeks or longer before you experience any improvement in your symptoms. Continue to take Sizosure 80 Tablet 10's even if you feel well, and do not stop taking it without talking to your doctor.

Yes, Sizosure 80 Tablet 10's can cause dizziness, fainting, and lightheadedness when you stand up too quickly after lying down. This is more likely to happen when you first start taking Sizosure 80 Tablet 10's or if your dose changes. To help prevent this problem, rise slowly from the bed and allow your feet to rest on the floor for a few minutes before standing up.

Country of origin

India

Manufacturer/Marketer address

Ikon Pharmachem
Other Info - SIZ0092

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/cdi/lurasidone.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/200603s015lbl.pdf
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