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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:30 PM IST

Sintrim 15 mg Tablet is an anti-obesity drug used to treat obesity and overweight. It contains Sibutramine, which causes weight loss by suppressing the appetite and promoting energy expenditure. It is recommended for obese patients with an initial body mass index (BMI) ≥ 30 kg/m2 or ≥ 27 kg/m2. Common side effects of Sintrim 15 mg Tablet include dry mouth, headache, loss of appetite, trouble sleeping, and constipation.

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Synonym

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE

Composition

SIBUTRAMINE-15MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Sintrim 15 mg Tablet

Sintrim 15 mg Tablet belongs to the class of medication called anti-obesity drugs used to treat obesity and help lose weight. Sintrim 15 mg Tablet is recommended for obese patients with an initial body mass index (BMI) ≥ 30 kg/m2 or ≥ 27 kg/m2 in the presence of other risk factors (e.g., dyslipidemia or Abnormally elevated cholesterol or fats, diabetes, controlled hypertension). Sintrim 15 mg Tablet should be used along with a low-calorie diet and regular physical exercise. Obesity is a medical condition caused by excess body fat, making a person overweight and predisposing them to many conditions and disorders. Intake of more calories than you burn by exercise or daily activities results in obesity.

Sintrim 15 mg Tablet contains Sibutramine which causes weight loss by suppressing the appetite and promoting energy expenditure.

Take Sintrim 15 mg Tablet as prescribed by your doctor. You are advised to take Sintrim 15 mg Tablet for as long as your doctor has prescribed it for you based on your condition. Some people may experience dry mouth, headache, loss of appetite, trouble sleeping, and constipation. Most of these side effects of Sintrim 15 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Sintrim 15 mg Tablet is contraindicated in patients with hypersensitivity to Sibutramine or any of the inactive ingredients in it. Sintrim 15 mg Tablet is contraindicated in patients receiving monoamine oxidase inhibitors (MAOIs) or other centrally acting weight loss drugs. It is recommended not to use in patients with a major eating disorder (anorexia nervosa or bulimia nervosa). The use of Sintrim 15 mg Tablet during pregnancy and breastfeeding is not recommended. The efficacy of Sibutramine in adolescents who are obese has not been adequately studied. The concomitant use of Sintrim 15 mg Tablet and excess alcohol is not recommended.

Uses of Sintrim 15 mg Tablet

Treatment of Obesity and overweight

Medicinal Benefits

Sintrim 15 mg Tablet contains Sibutramine, an anti-obesity drug indicated for managing obesity, including weight loss and maintenance of weight loss, and should be used in conjunction with a reduced-calorie diet. Sintrim 15 mg Tablet is recommended for obese patients with an initial body mass index (BMI) ≥ 30 kg/m2 or ≥ 27 kg/m2 in the presence of other risk factors (e.g., dyslipidemia or Abnormally elevated cholesterol or fats, diabetes, controlled hypertension). Sibutramine causes weight loss by suppressing the appetite and by promoting energy expenditure. Sintrim 15 mg Tablet should be used along with a low-calorie diet and regular physical exercise. Thus, Sintrim 15 mg Tablet promotes weight loss and lowers the possibility of developing major health issues.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sintrim 15 mg Tablet

  • Dry mouth
  • Headache
  • Loss of appetite
  • Trouble sleeping
  • Constipation

Drug Warnings

If you have an allergy to any ingredient in Sintrim 15 mg Tablet , it is advised that you avoid using it. While taking Sintrim 15 mg Tablet , women who are sexually active should use effective contraception. Patients should be instructed to inform their doctor immediately if they get pregnant or plan to get pregnant while taking Sintrim 15 mg Tablet . Sibutramine or its metabolites may be excreted in human milk; however, this is unknown. Therefore, using Sintrim 15 mg Tablet while breastfeeding is not advised. Since there is little knowledge on utilizing Sintrim 15 mg Tablet in teens, it is advised against doing so. Inform your doctor about your medical history and the other drugs you are currently taking before taking Sintrim 15 mg Tablet to rule out any possible side effects or interactions.

Drug Interactions

Drug-Drug Interactions: Sintrim 15 mg Tablet may interact with monoamine oxidase inhibitors or antidepressants (e.g. isocarboxazid, phenelzine, citalopram, clomipramine, doxepin), medicines used to prevent nausea and vomiting in certain conditions (e.g. ondansetron), medicines used to treat the symptoms of migraine headaches (e.g. sumatriptan) and other centrally acting weight loss drugs (e.g. merastin).

Drug-Food Interactions: Avoid high-fat meals and alcoholic beverages.

Drug-Disease Interactions: Sintrim 15 mg Tablet may interact with disease conditions, including anorexia nervosa (An eating disorder), cardiovascular disorders, glaucoma (eye conditions that can cause blindness) and renal/liver disease.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • CITALOPRAM
  • CLOMIPRAMINE
  • DOXEPIN
  • ONDANSETRON
  • SUMATRIPTAN
  • MERASTIN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a low-fat diet. Prefer skim milk and fat-free or low-fat dairy products.
  • Avoid red meat and include lean meat such as salmon and chicken.
  • Eat a healthy diet that includes fruits, vegetables, lean protein and whole grains.
  • Avoid fried foods, fast food, instant food, pasta, burger, noodles and cookies.
  • Limit your sugar intake, as excess sugar is stored as fat in the body.
  • Do not skip meals to reduce weight but instead, take balanced meals.
  • Do regular exercise such as swimming, cycling, walking or dancing for a minimum of 20 to 30 minutes daily.
  • Avoid alcohol consumption.

Disease/Condition Glossary

Obesity: Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity. Some common causes of obesity include insufficient sleep, growing older, pregnancy, genetics, hypothyroidism (underactive thyroid gland) or polycystic ovary syndrome (imbalance of female reproductive hormones). Proper diet and exercise are advised, along with medication to treat obesity.

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Alcohol

Caution

Do not consume alcohol while on treatment with Sintrim 15 mg Tablet as it may cause serious side effects.

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Pregnancy

Caution

No adequate and well-controlled studies with Sintrim 15 mg Tablet have been conducted on pregnant women. So, the use of Sintrim 15 mg Tablet during pregnancy is not recommended.

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Breast Feeding

Caution

It is unknown whether sibutramine is excreted in human milk. Therefore, Sintrim 15 mg Tablet is not recommended for use in nursing mothers.

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Driving

Safe if prescribed

It is not known whether Sintrim 15 mg Tablet alters the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Patients with severe hepatic dysfunction have not been systematically studied; Sintrim 15 mg Tablet should not be used in such patients.

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Kidney

Caution

Patients with mild to severe renal impairment should use Sintrim 15 mg Tablet with caution. Patients with severe renal impairment, such as those receiving dialysis for end-stage renal disease, should not utilize Sintrim 15 mg Tablet .

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Children

Unsafe

It is unknown if sibutramine is safe and effective for use in pediatric patients under the age of 16.

Country of origin

India
Other Info - SIN0066

Author Details

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FAQs

Sintrim 15 mg Tablet is used to treat Obesity and overweight.
Sintrim 15 mg Tablet contains Sibutramine, an anti-obesity drug that causes weight loss by suppressing the appetite and promoting energy expenditure. Sintrim 15 mg Tablet should be used along with a low-calorie diet and regular physical exercise. Thus, Sintrim 15 mg Tablet promotes weight loss and lowers the possibility of developing major health issues.
Sintrim 15 mg Tablet substantially increases some patients' blood pressure and/or pulse rate. Regular pulse rate and blood pressure monitoring is required when prescribing Sintrim 15 mg Tablet .
If you take too much Sintrim 15 mg Tablet , call your doctor or Poison Control Center immediately, or go to the emergency room.
Sintrim 15 mg Tablet is contraindicated in patients with major eating disorders (anorexia nervosa or bulimia nervosa).

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