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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Sinarest Syrup is used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Also, it works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, sleepiness, nausea, fatigue, vomiting, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Centaur Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Sinarest Syrup

Sinarest Syrup belongs to a class of medication called 'cough and cold medications' primarily used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.

Sinarest Syrup is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic agent; it helps to loosen mucus, making it easier to cough out.

Take Sinarest Syrup as prescribed. Your doctor will recommend how often you take Sinarest Syrup based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, vomiting, and headache. Everyone doesn't need to experience the above side effects. In some cases, Sinarest Syrup may cause a severe allergic skin reaction, probably due to paracetamol, which may disappear in some time.

Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Sinarest Syrup. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Sinarest Syrup as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinarest Syrup if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Sinarest Syrup should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.

Uses of Sinarest Syrup

Treatment of Common cold symptoms like sneezing, watery eyes, or itchy/watery nose and throat.

Medicinal Benefits

Sinarest Syrup is primarily used to treat common cold symptoms. It is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic) and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic, it helps to loosen mucus, making it easier to cough out.

Directions for Use

Use Sinarest Syrup as advised by the doctor. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sinarest Syrup

  • Drowsiness
  • Sleepiness
  • Nausea
  • Fatigue
  • Vomiting
  • Headache

Drug Warnings

If you are allergic to Sinarest Syrup or any other medicines, please tell your doctor. Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Sinarest Syrup. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Sinarest Syrup as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinarest Syrup if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Sinarest Syrup should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.

Drug Interactions

Drug-Drug Interaction: Sinarest Syrup may interact with anti-allergic medications (diphenhydramine, cetirizine), antidepressant medications (duloxetine, imipramine, amitriptyline), anticonvulsants medications (clonazepam), antianxiety medication (alprazolam), cough suppressants (dextromethorphan), and bronchodilator (albuterol).

Drug-Food Interaction: Avoid intake of Sinarest Syrup with alcohol as they may cause increased drowsiness, dizziness, and difficulty concentrating.

Drug-Disease Interaction: If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, Raynaud's phenomenon (decreased blood flow to the fingers), enlarged prostate gland,  kidney, liver, heart, or urinary problems, inform your doctor before taking Sinarest Syrup.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • IMIPRAMINE
  • AMITRIPTYLINE
  • CLONAZEPAM
  • ALPRAZOLAM
  • DEXTROMETHORPHAN
  • ALBUTEROL

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
  • Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Sinarest Syrup as it may cause tiredness, drowsiness, or lack of concentration.

Special Advise

  • Avoid alcohol consumption with Sinarest Syrup as it may cause tiredness, drowsiness, or lack of concentration. 
  • Do not take Sinarest Syrup if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, consult your doctor.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Sinarest Syrup to avoid excessive drowsiness and sleepiness.

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Pregnancy

Caution

The safety of Sinarest Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Sinarest Syrup is known to pass through milk in small amounts. Use in breastfeeding women is not recommended as it may cause unpleasant side effects to the baby like unusual irritability, excitement.

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Driving

Unsafe

Sinarest Syrup is known to cause drowsiness, so please do not drive or operate any machinery which requires concentration.

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Liver

Caution

Take Sinarest Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Sinarest Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Sinarest Syrup is not recommended for children below 2 years. However, it can be given to children more than 2 years of age only if the doctor has prescribed it.

Country of origin

INDIA

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - SIN0003

Author Details

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FAQs

Sinarest Syrup is used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat.
Sinarest Syrup is a combination of four different medicines,  Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic; it helps to loosen mucus, making it easier to cough out.
It is not recommended to take a higher than the recommended dose as it may lead to unpleasant side effects and toxicity. If you feel the severity of your symptoms is increasing, please consult your doctor.
Do not use Sinarest Syrup if you have used any MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Sinarest Syrup if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing your skin or eyes). In rare cases, paracetamol present in Sinarest Syrup may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Sinarest Syrup.
No, it would be best if you did not take Sinarest Syrup along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Sinarest Syrup.
It is not advisable to breastfeed while taking Sinarest Syrup as it contains Chlorpheniramine (an antihistamine), which is known to pass through the breast milk and may harm the baby. So, please consult the doctor before breastfeeding if you are taking Sinarest Syrup.
Sodium citrate is an additive and a mucolytic agent. It helps to loosen the mucus and hence makes it easier to cough out.

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