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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sinarest Syrup is used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Also, it works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, sleepiness, nausea, fatigue, vomiting, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Sinarest Syrup

Sinarest Syrup belongs to a class of medication called 'cough and cold medications' primarily used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.

Sinarest Syrup is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic agent; it helps to loosen mucus, making it easier to cough out.

Take Sinarest Syrup as prescribed. Your doctor will recommend how often you take Sinarest Syrup based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, vomiting, and headache. Everyone doesn't need to experience the above side effects. In some cases, Sinarest Syrup may cause a severe allergic skin reaction, probably due to paracetamol, which may disappear in some time.

Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Sinarest Syrup. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Sinarest Syrup as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinarest Syrup if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Sinarest Syrup should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.

Uses of Sinarest Syrup

Treatment of Common cold symptoms like sneezing, watery eyes, or itchy/watery nose and throat.

Directions for Use

Use Sinarest Syrup as advised by the doctor. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Sinarest Syrup is primarily used to treat common cold symptoms. It is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic) and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic, it helps to loosen mucus, making it easier to cough out.

How Sinarest Syrup Works

Sinarest Syrup is a combination of four different medicines, Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic agent; it helps to loosen mucus, making it easier to cough out.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sinarest Syrup

  • Drowsiness
  • Sleepiness
  • Nausea
  • Fatigue
  • Vomiting
  • Headache

What if I have taken an overdose of Sinarest Syrup

Do not take more than the prescribed dose of Sinarest Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Sinarest Syrup or any other medicines, please tell your doctor. Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Sinarest Syrup. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Sinarest Syrup as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Sinarest Syrup if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Sinarest Syrup should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). Increase in the intake of fluids to keep throat hydrated.

Drug-Drug Interactions

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PhenylephrineTranylcypromine
Critical
PhenylephrineFurazolidone
Critical

Drug-Drug Interactions

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PhenylephrineTranylcypromine
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Taking Tranylcypromine with Sinarest Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Sinarest Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Taking Furazolidone with Sinarest Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Sinarest Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Sinarest Syrup 60 ml only after 14 days of stopping Furazolidone.
PhenylephrinePropofol
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Taking Sinarest Syrup 60 ml with Propofol may lead to increased levels of Sinarest Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Sinarest Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Co-administration of Selegiline with Sinarest Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Sinarest Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineSevoflurane
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Co-administration of Sinarest Syrup 60 ml with Sevoflurane can increase the levels of Sinarest Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Sinarest Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Taking Sinarest Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Sinarest Syrup 60 ml:
Taking Sinarest Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrineAmitriptyline
Severe
How does the drug interact with Sinarest Syrup 60 ml:
Co-administration of Amitriptyline with Sinarest Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Sinarest Syrup 60 ml and amitriptyline could interact, but they can still be taken if they are prescribed by a doctor. It is advised to monitor blood pressure regularly. Without consulting a doctor, never stop taking any medications.
PhenylephrineIsocarboxazid
Severe
How does the drug interact with Sinarest Syrup 60 ml:
Co-administration of Sinarest Syrup 60 ml with Isocarboxazid can result in extremely high blood pressure which may be serious.

How to manage the interaction:
Although taking Isocarboxazid and Sinarest Syrup 60 ml together can result in an interaction. However, if you develop a sudden, severe headache, blurred vision, confusion, chest pain, nausea, or vomiting, sudden numbness or weakness (particularly on one side of the body), difficulty speaking, fever, sweating, lightheadedness, or fainting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrineClomipramine
Severe
How does the drug interact with Sinarest Syrup 60 ml:
Co-administration of Clomipramine and Sinarest Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Clomipramine and Sinarest Syrup 60 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
  • Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Sinarest Syrup as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Sinarest Syrup Substitute

Substitutes safety advice
  • Sinarest Syrup 75 ml

    1.76per tablet
  • Sinarest Syrup 100 ml

    1.32per tablet
  • Flucol Syrup 60 ml

    0.99per tablet
  • Snownil Syrup 60 ml

    1.13per tablet
  • Kufma JR Bubble Gum Flavour Syrup 60 ml

    1.18per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Sinarest Syrup to avoid excessive drowsiness and sleepiness.

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Pregnancy

Caution

The safety of Sinarest Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Sinarest Syrup is known to pass through milk in small amounts. Use in breastfeeding women is not recommended as it may cause unpleasant side effects to the baby like unusual irritability, excitement.

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Driving

Unsafe

Sinarest Syrup is known to cause drowsiness, so please do not drive or operate any machinery which requires concentration.

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Liver

Caution

Take Sinarest Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Sinarest Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Sinarest Syrup is not recommended for children below 2 years. However, it can be given to children more than 2 years of age only if the doctor has prescribed it.

FAQs

Sinarest Syrup is used to treat the common cold like sneezing, watery eyes, or itchy/watery nose and throat.
Sinarest Syrup is a combination of four different medicines,  Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Sodium Citrate (mucolytic). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Sodium citrate is a mucolytic; it helps to loosen mucus, making it easier to cough out.
It is not recommended to take a higher than the recommended dose as it may lead to unpleasant side effects and toxicity. If you feel the severity of your symptoms is increasing, please consult your doctor.
Do not use Sinarest Syrup if you have used any MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Sinarest Syrup if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing your skin or eyes). In rare cases, paracetamol present in Sinarest Syrup may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Sinarest Syrup.
No, it would be best if you did not take Sinarest Syrup along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Sinarest Syrup.
It is not advisable to breastfeed while taking Sinarest Syrup as it contains Chlorpheniramine (an antihistamine), which is known to pass through the breast milk and may harm the baby. So, please consult the doctor before breastfeeding if you are taking Sinarest Syrup.
Sodium citrate is an additive and a mucolytic agent. It helps to loosen the mucus and hence makes it easier to cough out.

Country of origin

INDIA

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - SIN0003

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