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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 2:45 PM IST
Sinarest Plus Suspension is a combination medicine primarily used in the treatment of allergic rhinitis and common cold. This medicine works by inhibiting the action of histamine, a chemical messenger responsible for causing allergies. It helps relieve congestion, sneezing, nasal and sinus congestion, and nasal swelling caused due to allergies. Common side effects include drowsiness, nervousness, mild headache, dizziness, insomnia, blurred vision, nausea, vomiting, constipation, and dry mouth.
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About Sinarest Plus Suspension

Sinarest Plus Suspension is used to treat symptoms of the common cold and allergies (allergic rhinitis). The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as “rhinoviruses”. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks. Allergies are caused due to the 'allergens' that cause 'histamine' to release in the blood, thereby causing a stuffy nose, watery eyes, itching nose/throat, etc. 

Sinarest Plus Suspension is a combination of five drugs, namely: Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat and provides a cooling sensation.

Take Sinarest Plus Suspension as advised by your doctor. Some people may experience drowsiness, nervousness, mild headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, nausea, vomiting, constipation, and dry mouth. Most of these side effects of Sinarest Plus Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Sinarest Plus Suspension or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Sinarest Plus Suspension. Sinarest Plus Suspension is not recommended for children below 2 years of age. Please do not take more than the prescribed dose of Sinarest Plus Suspension as it may cause liver damage and severe adverse effects. If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Sinarest Plus Suspension.

Uses of Sinarest Plus Suspension

Treatment of Common cold and Allergies

Medicinal Benefits

Sinarest Plus Suspension contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol used to treat symptoms of the common cold and allergies. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an anti-allergic drug that blocks the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, helps to cough out easily. Menthol is a cooling agent that relieves minor irritation in the throat and provides a cooling sensation. Together Sinarest Plus Suspension helps relieve symptoms of a common cold like headache, fever, and allergies like stuffy nose, watery eyes, itching nose/throat, etc.

Side Effects of Sinarest Plus Suspension

  • Drowsiness
  • Nervousness
  • Mild headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Nausea
  • Vomiting
  • Constipation
  • Dry mouth

Directions for Use

Check the label for directions before use. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Sinarest Plus Suspension or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Sinarest Plus Suspension. Sinarest Plus Suspension is not recommended for children below 2 years of age. Please do not take more than the prescribed dose of Sinarest Plus Suspension as it may cause liver damage and severe adverse effects.  Avoid using Sinarest Plus Suspension if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Sinarest Plus Suspension.

Therapeutic Class

ANTIALLERGIC

Drug-Drug Interactions

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PhenylephrineTranylcypromine
Critical
PhenylephrinePropofol
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid consumption of alcohol with Sinarest Plus Suspension as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

How Sinarest Plus Suspension Works

Sinarest Plus Suspension is a combination of five drugs, namely: Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat and provides a cooling sensation.

What if I have taken an overdose of Sinarest Plus Suspension

Avoid exceeding the recommended dose as it might cause an overdose. Consult the doctor if you suspect you have taken an overdose or experience any unusual symptoms.
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Alcohol

Unsafe

Avoid consumption of alcohol with Sinarest Plus Suspension as it may cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Sinarest Plus Suspension.

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Pregnancy

Caution

The safety of Sinarest Plus Suspension in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

Sinarest Plus Suspension may be excreted in breast milk and cause harm to the baby. Therefore, Sinarest Plus Suspension should not be used in breastfeeding mothers without doctor’s advice.

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Driving

Caution

Sinarest Plus Suspension may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Sinarest Plus Suspension.

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Liver

Caution

Take Sinarest Plus Suspension with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Sinarest Plus Suspension with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Sinarest Plus Suspension is not recommended for children below 2 years of age, as the safety and effectiveness were not established. However, please consult a doctor before giving Sinarest Plus Suspension to children.

Country of origin

INDIA

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - SIN0015

Author Details

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Sinarest Plus Suspension Substitute

Substitutes safety advice
  • Sinarest Plus Suspension 75 ml

    1.78per tablet

FAQs

Sinarest Plus Suspension is used to treat symptoms of the common cold and allergies (allergic rhinitis).
Sinarest Plus Suspension contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, Sodium citrate, and menthol. Paracetamol blocks messengers that cause pain. Phenylephrine hydrochloride works by contracting and narrowing the nasal blood vessels. Chlorpheniramine maleate blocks the action of histamine (a substance responsible for causing allergic reactions). Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Menthol relieves minor irritation in the throat due to allergy and provides a cooling sensation. Together Sinarest Plus Suspension prevents symptoms of the common cold and allergic rhinitis.
Sinarest Plus Suspension may be used to relieve pain and fever associated with cold. Paracetamol in Sinarest Plus Suspension is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
You are not recommended to take Sinarest Plus Suspension with cetirizine as co-administration of these two medicines may increase adverse effects such as drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking Sinarest Plus Suspension with other medicines.
You are not recommended to take more than the prescribed dose of Sinarest Plus Suspension as it may cause liver damage and lead to severe adverse effects. Therefore, take Sinarest Plus Suspension only in doses as advised by a doctor.
Sinarest Plus Suspension may not be suitable for patients with high blood pressure because of the presence of phenylephrine in its composition, which can increase blood pressure by narrowing blood vessels. If you have high blood pressure, inform your doctor before taking this medication to avoid potential complications.
While you are suffering from viral flu, taking some precautions for a quick recovery and avoiding spreading it to others is essential. Get plenty of rest and avoid public places. Drink lots of fluids like water, herbal teas, and broths to stay hydrated. Cover your mouth and nose with a tissue or your elbow when you cough or sneeze and wash your hands regularly with soap. Avoid close contact with others to prevent the spread of the flu virus. Manage symptoms with over-the-counter medications and seek medical attention if symptoms worsen.
No, Sinarest Plus Suspension is not used to treat asthma coughs. It's used to treat common cold symptoms and allergies (allergic rhinitis). It is not effective for asthma coughs. Consult your doctor for a proper diagnosis and treatment plan for an asthma cough. They may prescribe medications specifically suitable for treating asthma
Sinarest Plus Suspension might cause drowsiness as it is a commonly reported side effect. If you experience drowsiness, rest is advised. This effect generally doesn't require medical attention and usually resolves over time. However, if the drowsiness persists or worsens, please consult your doctor.
Yes, Sinarest Plus Suspension can be used to treat a runny nose. It contains chlorpheniramine, an antihistamine that helps relieve allergy symptoms like runny nose, sneezing, and watery eyes.
The common side effects of Sinarest Plus Suspension are drowsiness, nervousness, mild headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, nausea, vomiting, constipation, and dry mouth. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

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