SINAREST FXP TABLET belongs to the class of medications called ‘cough and cold preparations’ used in the treatment of the common cold and allergic symptoms such as the runny nose, sneezing, itchy or watery eyes and blocked nose. The common cold is a respiratory illness of the nose and throat caused by ‘rhinoviruses’. Allergies are immune system reactions to foreign bodies or allergens such as certain foods, chemicals, pet dander, or pollen.

SINAREST FXP TABLET contains Fexofenadine, Paracetamol, and Phenylephrine. Fexofenadine is an antiallergic medicine. It blocks the release of histamine, chemical substances that cause allergic symptoms such as the runny nose, watery eyes, itching, sneezing, and swelling or congestion. Paracetamol is an analgesic (reduce pain) and antipyretic (reduce fever). It can block the production of prostaglandins (chemical substances), thereby decreasing pain, swelling, and inflammation. Phenylephrine is a decongestant that can reduce swelling in the nasal passages making it easy to breathe.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of SINAREST FXP TABLET are nausea, vomiting, headache, ear pain, trouble sleeping, restlessness, and palpitations (pounding heart). These side-effects usually go away without requiring any medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take SINAREST FXP TABLET if you are allergic to any contents of it. It should not be used in patients with severe liver failure. It should be used with caution in children, patients with liver or kidney disease, pregnant women, breastfeeding mothers, and elderly people. Alcohol increases the risk of side-effects. SINAREST FXP TABLET may decrease alertness, so do not drive or operate heavy machinery if you are not fully alert.

SINAREST FXP TABLET is composed of three medicines, namely Fexofenadine, Paracetamol, and Phenylephrine. Fexofenadine is an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandin's responsible for pain and fever. Phenylephrine helps in shrinking the blood vessels in the nostrils and the nasal passage and reducing stuffy nose. Together, SINAREST FXP TABLET can effectively treat common cold and allergy symptoms.

• Nausea
• Vomiting
• Headache
• Ear pain
• Trouble sleeping
• Restlessness
• Palpitations (pounding heart)

Do not take SINAREST FXP TABLET if you have been taking medicines to treat depression (monoamine oxidase inhibitors) such as selegiline and rasagiline in the past 14 days. Before taking SINAREST FXP TABLET , inform your doctor if you have any liver or kidney disease, diabetes, hyperactive thyroid, heart problems, fits, and glaucoma (increased pressure in the eye). SINAREST FXP TABLET may cause liver damage on prolonged use or when used in high doses, so it is not recommended for use in patients with severe liver failure.

Drug-Drug Interactions: SINAREST FXP TABLET may interact with medicines used to treat nausea and vomiting (domperidone and metoclopramide), antidepressants (phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, imipramine, and desipramine, etc.), anticoagulant (warfarin), a medicine used to treat high cholesterol (cholestyramine), medicines used to treat fits, anti-HIV drug (zidovudine), narcotic pain killers (codeine and morphine), antibiotic (chloramphenicol), medicines used to treat asthma (epinephrine and formoterol), antacids (magnesium hydroxide and aluminium hydroxide), and medicines used to treat high blood pressure (methyldopa and reserpine).

Drug-Food Interactions: Avoid consumption of grapefruit juice and alcohol as it may increase the risk of side-effects.

Drug-Disease Interactions: SINAREST FXP TABLET should not be used in patients with severe liver failure. It should be used with caution in patients with liver or kidney disease, diabetes, hyperactive thyroid, heart problems, fits, and glaucoma (increased pressure in the eye).

• DOMPERIDONE
• METOCLOPRAMIDE
• PHENELZINE
• PROCARBAZINE
• RASAGILINE
• SELEGILINE
• TRANYLCYPROMINE
• IMIPRAMINE
• DESIPRAMINE
• WARFARIN
• CHOLESTYRAMINE
• ZIDOVUDINE
• CODEINE
• MORPHINE
• CHLORAMPHENICOL
• EPINEPHRINE
• FORMOTEROL
• MAGNESIUM HYDROXIDE
• ALUMINIUM HYDROXIDE
• METHYLDOPA
• RESERPINE

• Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose, and sneezing.
• The immune system is affected by stress and raises the risk of being sick. An individual can exercise regularly, meditate, do deep breathing, and try progressive muscle relaxation techniques to relieve stress.
• To stay fit and safe, try to sleep at least 8 hours each night.
• It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
• Maintain personal hygiene and keep your surroundings clean.

• If you are undergoing an allergy test, the doctor might advise you to stop SINAREST FXP TABLET 5 days before the test as this medicine may interfere with the test results.
• Check the labels carefully before taking any over-the-counter (OTC) medicines as many pain and cold medicines contain paracetamol as an ingredient.

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

Allergies: It occurs when foreign elements that cause allergy (allergens) attack and invade our body, causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.