Siluri-D4 Capsule Combipack is a combination of medicine primarily used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or urge to urinate more often and improve your ability to urinate. The prostate is a small, muscular gland in the male reproductive system. Enlargement of the prostate is called BPH common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder.

Siluri-D4 Capsule Combipack is a combination of two drugs, namely; Silodosin and Dutasteride. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Siluri-D4 Capsule Combipack reduces the BPH symptoms and improves your ability to urinate.

Take Siluri-D4 Capsule Combipack as prescribed. Your doctor will recommend how often you take Siluri-D4 Capsule Combipack based on your medical condition. In some cases, you may experience certain common side effects such as dizziness, headache, nasal congestion (stuffy nose), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually continue taking Siluri-D4 Capsule Combipack for as long as your doctor has prescribed it. Try not to stop taking it on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Siluri-D4 Capsule Combipack. Avoid consumption of alcohol as it may increase the side effects like dizziness and low blood pressure. If you take Siluri-D4 Capsule Combipack with any antihypertensive medicine, your blood pressure could suddenly drop to s life-threatening level. So avoid intake of Siluri-D4 Capsule Combipack with antihypertensive drugs.

Siluri-D4 Capsule Combipack is a combination of two drugs, namely; Silodosin and Dutasteride used to treat the symptoms of benign prostatic hyperplasia (BPH) in adults with an enlarged prostate gland. Silodosin belongs to a class of alpha-1 receptors (located in prostate and bladder) blocker that works by blocking the action of alpha-1 receptors and causes smooth muscle relaxation in the bladder and prostate. Dutasteride belongs to a class of 5-alpha reductase that works by blocking the action of a 5-alpha reductase enzyme, resulting in a shrink of the size of the prostate gland. Siluri-D4 Capsule Combipack reduces the BPH symptoms and improves your ability to urinate.

• Headache
• Dizziness
• Nasal congestion (stuffy nose)
• Diarrhoea
• Ejaculation disorder
• Retrograde ejaculation
• Impotence
• Orthostatic hypotension (sudden lowering of blood pressure on standing)

Do not take Siluri-D4 Capsule Combipack if you are allergic to Siluri-D4 Capsule Combipack and ingredients in it. Consult your doctor before taking Siluri-D4 Capsule Combipack if you are taking medicines for the treatment of hypertension (high blood pressure). If you take Siluri-D4 Capsule Combipack with any antihypertensive medicine your blood pressure could suddenly drop to a life-threatening level. So avoid intake of Siluri-D4 Capsule Combipack with antihypertensive drugs. Do not take Siluri-D4 Capsule Combipack if you have/had a heart attack or stroke or heart failure, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve. You are advised not to drive or operate heavy machinery after taking Siluri-D4 Capsule Combipack as it may cause dizziness. Avoid consuming alcohol along with Siluri-D4 Capsule Combipack as it could lead to increased dizziness and drowsiness. Older patients may be more sensitive to the side effects of Siluri-D4 Capsule Combipack, especially dizziness and low blood pressure when getting up from a sitting or lying position. Siluri-D4 Capsule Combipack should not be given to women and children less than 18 years of age.

Drug-Drug Interaction: Siluri-D4 Capsule Combipack interacts with medicines used to treat high blood pressure (prazosin, terazosin), drugs used to treat erectile dysfunction (sildenafil, tadalafil), azole antifungals (itraconazole, ketoconazole), HIV protease inhibitor (lopinavir, ritonavir).

Drug-Food Interaction: Siluri-D4 Capsule Combipack may interact with grapefruit juice, alcohol, and tobacco. This may cause more side effects than it normally does. So, a Siluri-D4 Capsule Combipack should not be taken along with them.

Drug-Disease Interaction: Siluri-D4 Capsule Combipack should not be taken in patients with heart problems, low blood pressure, kidney or liver disease, have certain eye diseases, loss of vision due to loss of blood flow to the optic (eye) nerve.

• PRAZOSIN
• TERAZOSIN
• SILDENAFIL
• TADALAFIL
• ITRACONAZOLE
• KETOCONAZOLE
• LOPINAVIR
• RITONAVIR

• Maintaining a healthy weight, eating a balanced diet, and regular exercising may help your bladder empty at a normal rate.

• Avoid consumption of alcohol to treat your condition effectively as consuming an excessive amount of alcohol may make you pee more and can irritate your bladder.

•  Limit the amount of fluids and caffeine you drink, especially before you go out or go to bed.

• Stay warm, cold can make it feel more urgent to pee.

• Avoid usage of tobacco.

• Do daily exercise to strengthen your pelvic floor muscles.

• Regularly monitor blood pressure is required while taking Siluri-D4 Capsule Combipack.

Benign Prostatic Hyperplasia (BPH): is an enlargement of the prostate gland. The prostate is a small, muscular gland in the male reproductive system. It is a common condition as men get older (50-60 years). It occurs when the cells of the prostate gland begin to multiply. In an enlarged prostate gland, the bladder wall becomes thicker, and the bladder may weaken and lose the ability to empty fully, leaving some urine in the bladder. Symptoms of BPH include frequent or urgent need to urinate, nocturia (increased frequency of urination at night, difficulty starting urination, inability to empty the bladder, painful urination, blood in the urine.