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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 2:45 PM IST
Silpraz 40 mg Injection belongs to the class of proton pump inhibitors. It is used as a short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It contains esomeprazole, which helps decrease the amount of acid in the stomach. Some of the common side effects include headache, diarrhoea, constipation, abdominal pain, flatulence, vomiting, nausea, etc.
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Prescription drug

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Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Silver Bio-Tech

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Silpraz 40 mg Injection

Silpraz 40 mg Injection belongs to the class of drugs known as proton pump inhibitors used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults. Silpraz 40 mg Injection is indicated in adults and children aged 1 month or older who have had damage to their oesophagus and are unable to take esomeprazole by mouth.

Silpraz 40 mg Injection contains 'Esomeprazole' that works by reducing the amount of acid made in the stomach. As a result, it relieves symptoms of gastroesophageal reflux disease (GERD) and stomach ulcers.

Silpraz 40 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Silpraz 40 mg Injection may cause headache, diarrhoea, stomach pain, constipation, wind (flatulence), nausea, vomiting, and injection site reactions such as pain, itching, swelling or redness. Most of these side effects do not require medical attention and may resolve with time. However, if they persist or worsen, consult a doctor.

Do not take Silpraz 40 mg Injection if you have/had any allergy or hypersensitivity to esomeprazole, any other proton pump inhibitor medications (such as pantoprazole, lansoprazole, rabeprazole, or omeprazole), or any of the other ingredients in Silpraz 40 mg Injection. Let your doctor know if you are taking nelfinavir (used to treat HIV infection). Consult your doctor if you are breastfeeding, pregnant, or intend to become pregnant. 

Uses of Silpraz 40 mg Injection

Treatment of Gastroesophageal reflux disease (GERD) and stomach ulcers

Medicinal Benefits

Silpraz 40 mg Injection contains esomeprazole which belongs to the class of drugs known as proton pump inhibitors used to treat gastroesophageal reflux disease (heartburn) and stomach ulcers caused by the use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). It is also used to reduce the risk of further ulcer bleeding following an endoscopy in adults. Silpraz 40 mg Injection works by irreversibly blocking the proton pump gate (which secretes stomach acid), thereby reducing stomach acid and treating acidity-related conditions.

Side Effects of Silpraz 40 mg Injection

  • Headache
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Wind (flatulence)
  • Nausea
  • Vomiting
  • Injection site reaction
  • Benign polyps in the stomach

Directions for Use

Silpraz 40 mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

You should avoid taking Silpraz 40 mg Injection if you are allergic to any of its components, other proton pump inhibitors or if you are taking certain HIV medications such as nelfinavir. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects/interactions. Consult your doctor if you are a pregnant woman/nursing mother. Let your doctor know if you have liver/kidney problems or if you are due to undergo Chromogranin A test. Taking Silpraz 40 mg Injection for more than a year may modestly raise your risk of hip, wrist, or spine fracture. If you use corticosteroids (which can increase the risk of osteoporosis) or have osteoporosis, tell your doctor.

Therapeutic Class

ANTACIDS

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical
EsomeprazoleDasatinib
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows. Instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid alcohol and smoking. Alcohol can raise the production of stomach acid leading to heartburn and acid reflux. On the other hand, smoking damages the sphincter, which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green vegetables (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pyroli infection.
  • Avoid sitting continuously as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

How Silpraz 40 mg Injection Works

Silpraz 40 mg Injection contains 'Esomeprazole' that works by reducing the amount of acid made in the stomach. As a result, it relieves symptoms of gastroesophageal reflux disease (GERD) and stomach ulcers.

What if I have taken an overdose of Silpraz 40 mg Injection

A healthcare professional administers Silpraz 40 mg Injection in a hospital setting. Hence, the chances of overdose are less. If you experience stomach cramps, bloating, watery, severe diarrhea that occasionally turns bloody, fever, nausea, vomiting, or unusual weakness or tiredness, consult your doctor right away.
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Alcohol

Caution

Drinking alcohol or alcoholic beverages with Silpraz 40 mg Injection may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid/limit alcohol.

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Pregnancy

Caution

Consult a doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Silpraz 40 mg Injection.

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Breast Feeding

Caution

Consult a doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Silpraz 40 mg Injection.

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Driving

Caution

In rare cases, Silpraz 40 mg Injection may cause dizziness and impaired vision. Do not drive if you experience these symptoms.

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Liver

Caution

Silpraz 40 mg Injection should be taken with precaution in patients with liver disease. Inform your doctor before receiving Silpraz 40 mg Injection if you have had a liver impairment/disorder history. The doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Silpraz 40 mg Injection should be taken with precaution in patients with kidney disease. Inform your doctor before receiving Silpraz 40 mg Injection if you have had a history of severe kidney impairment/disorder. The doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Silpraz 40 mg Injection can be given to children aged 1 month or older under the supervision of a healthcare provider.

Country of origin

India

Manufacturer/Marketer address

Sanify Healthcare Private Limited, Sandeep Arora(Assistant Marketing Manager) Shri Sai Market, Opposite Hotel Marc Royale, Kalka- Zirakpur Highway, Dhakoli, Dhakauli, Zirakpur ? 140603, Punjab, India
Other Info - SIL0472

Author Details

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FAQs

Silpraz 40 mg Injection belongs to the class of drugs known as proton pump inhibitors used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults.
Silpraz 40 mg Injection impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach, thereby helps treat GERD.
No. Gas and acidity are two different conditions. Acidity is caused due to improper functioning of the valve (sphincter) located at the junction of the stomach and food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.
On long-term treatment, Silpraz 40 mg Injection may cause low magnesium levels. Low magnesium levels can make you tired, confused, and dizzy and cause muscle cramps, shakiness, and an irregular heartbeat. Inform the doctor if you experience any of these symptoms.
Silpraz 40 mg Injection may alter certain medical tests like secretin stimulation tests and urine screening tests for tetrahydrocannabinol (THC). So, if you are undergoing diagnostic tests inform your doctor that you are taking Silpraz 40 mg Injection.
Silpraz 40 mg Injection may slightly increase the risk of hip, wrist, or spine fracture, especially if you take it for longer than a year. Let your doctor know if you have osteoporosis or are taking corticosteroids (which can increase the risk of osteoporosis).

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