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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Silectone 100 Tablet is used to remove excess water from the body and treat fluid overload (oedema). It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure due to oedema (fluid retention). It contains Spironolactone, which is prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). It works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, you may experience low blood pressure, dehydration, dizziness, electrolyte disturbances (potassium and sodium), increased creatinine level in the blood, headache, nausea, and breast enlargement in males.
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Manufacturer/Marketer :

Johnlee Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Silectone 100 Tablet

Silectone 100 Tablet is used to remove excess water from the body and treat fluid overload (oedema). It also maintains the bloodstream's potassium level and prevents hypertension (high blood pressure due to oedema (fluid retention). Oedema or fluid overload is associated with pulmonary hypertension (high blood pressure in the lung) or heart failure (irregular heart pumping). Leg swelling is the main characteristic of oedema, accompanied by shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in other hands or abdomen areas.

Silectone 100 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Silectone 100 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Your doctor will advise you how often you take Silectone 100 Tablet based on your medical condition. In some cases, you may experience low blood pressure (hypotension), dehydration, dizziness, electrolyte disturbances (potassium and sodium), increased creatinine levels in the blood, headache, nausea, and breast enlargement in males. Most of these side effects of Silectone 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Silectone 100 Tablet of your own as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you are suffering from any kidney, liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Silectone 100 Tablet can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to Silectone 100 Tablet. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Silectone 100 Tablet

Treatment of Hypertension (high blood pressure), Edema/Oedema (fluid overload)

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Silectone 100 Tablet contains 'Spironolactone', which acts as a short-acting diuretic (water pill) prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Silectone 100 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

How Silectone 100 Tablet Works

Silectone 100 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Silectone 100 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Silectone 100 Tablet

  • Low blood pressure (hypotension)
  • Dehydration
  • Dizziness
  • Electrolyte disturbances (potassium and sodium)
  • Increased creatinine level in the blood
  • Headache
  • Nausea
  • Breast enlargement in males

What if I have taken an overdose of Silectone 100 Tablet

Do not take more than the prescribed dose of Silectone 100 Tablet as it may cause overdose. The symptoms of overdose include feeling thirsty, urinating more than usual, diarrhoea, feeling or being sick, confusion, high potassium levels in blood or dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Silectone 100 Tablet should not be given to the people allergic to Silectone 100 Tablet, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, pregnant women, or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), anuria (unable to urinate), diabetes, and aortic stenosis (heart valve problem). Silectone 100 Tablet can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking Silectone 100 Tablet and breastfeeding. Do not take any extra potassium supplements or potassium-rich foods (bananas, broccoli) with Silectone 100 Tablet, as it may lead to an excessive increase in blood potassium level (hyperkalemia).
 

Drug-Drug Interactions

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SpironolactoneAmiloride
Critical
SpironolactoneEplerenone
Critical

Drug-Drug Interactions

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SpironolactoneAmiloride
Critical
How does the drug interact with Silectone 100 Tablet:
Coadministration of Amiloride with Silectone 100 Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Silectone 100 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactoneEplerenone
Critical
How does the drug interact with Silectone 100 Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Silectone 100 Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Spironolactonepotassium phosphate
Severe
How does the drug interact with Silectone 100 Tablet:
Taking Silectone 100 Tablet with potassium phosphate may increase potassium levels in the blood

How to manage the interaction:
Although taking Silectone 100 Tablet and potassium phosphate together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneTelmisartan
Severe
How does the drug interact with Silectone 100 Tablet:
Taking Silectone 100 Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Silectone 100 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
SpironolactoneColchicine
Severe
How does the drug interact with Silectone 100 Tablet:
Coadministration of colchicine and Silectone 100 Tablet increases blood levels of colchicine and its side effects.

How to manage the interaction:
Although taking Colchicine and Silectone 100 Tablet together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
SpironolactoneEnalapril
Severe
How does the drug interact with Silectone 100 Tablet:
Coadministration of enalapril with Silectone 100 Tablet may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Enalapril together with Silectone 100 Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, coconut water, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
SpironolactoneTrimethoprim
Severe
How does the drug interact with Silectone 100 Tablet:
Taking Silectone 100 Tablet with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Silectone 100 Tablet and trimethoprim together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneBenazepril
Severe
How does the drug interact with Silectone 100 Tablet:
Taking Silectone 100 Tablet with benazepril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Silectone 100 Tablet and benazepril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.
SpironolactoneFosinopril
Severe
How does the drug interact with Silectone 100 Tablet:
Using fosinopril together with Silectone 100 Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Taking Fosinopril with Silectone 100 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactoneVenetoclax
Severe
How does the drug interact with Silectone 100 Tablet:
Taking Silectone 100 Tablet with venetoclax may significantly increase the blood levels and side effects of venetoclax.

How to manage the interaction:
Although taking Silectone 100 Tablet and azilsartan medoxomil together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, diarrhea, fatigue, anemia (low numbers of blood cells), bleeding problems, and infections. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.

  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.

  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.

  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.

  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.

  • Avoid consumption of too much salt or salty food.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise like walking improves your blood flow.

  • When possible, elevate your legs or the swollen area on a chair or pillows.

  • Avoid standing or sitting for extended periods of time.

  • Avoid chronic stress as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

Silectone 100 Tablet Substitute

Substitutes safety advice
  • Aldactone 100 Tablet 15's

    15.30per tablet
  • Spilactone 100 mg Tablet 10's

    4.41per tablet
  • Cglactone 100mg Tablet

    7.65per tablet
  • Edeflow 100 Tablet

    7.65per tablet
  • Ascilact-100 Tablet 10's

    15.00per tablet
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Alcohol

Caution

You are recommended not to consume alcohol along with Silectone 100 Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Silectone 100 Tablet is not suggested during pregnancy since there is insufficient evidence on how it may impact a growing infant.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Silectone 100 Tablet.

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Driving

Unsafe

It is not recommended to drive after taking Silectone 100 Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from a lying position).

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Liver

Caution

Silectone 100 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Silectone 100 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Children

Unsafe

Silectone 100 Tablet is not recommended for children below 12 years of age.

FAQs

Silectone 100 Tablet is used to treat oedema (fluid overload) and hypertension (high blood pressure) due to oedema/fluid retention.
Silectone 100 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Silectone 100 Tablet works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future.
Yes, Silectone 100 Tablet may cause changes in the menstrual cycle. It can lead to irregular and painful periods. In addition to this, taking Silectone 100 Tablet can also lead to pain and swelling of the breast. If any of these problems persist and discomfort increases, please consult your doctor for the best advice.
Silectone 100 Tablet is known to increase the blood potassium level. So, if you take any extra potassium supplements or potassium-rich foods such as bananas and broccoli, it may lead to an excessive increase in potassium level and lead to hyperkalemia.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Store in a cool, dry place, away from heat and direct light. Keep Silectone 100 Tablet out of the sight and reach of children.
Avoid using potassium-rich supplements. Combining potassium-rich foods with spironolactone can result in elevated potassium levels. Excess potassium can cause irregular heartbeat, perhaps leading to a heart attack and other complications.
Silectone 100 Tablet is recommended not to be used during pregnancy and breastfeeding. If you have any concerns regarding a consult with your doctor.
As Silectone 100 Tablet is a potassium-sparing diuretic, you should avoid alcoholic beverages and potassium-containing supplements or sports drinks, as well as consuming too many high-potassium foods such as papaya, cantaloupe, prune juice, honeydew melons, bananas, raisins, mangoes, kiwis, oranges, orange juice, tomatoes, tomato juice, white and sweet potatoes, asparagus, pumpkin, and Brussels sprouts. Avoid salt replacements containing potassium chloride rather than sodium chloride and low-sodium milk products.
Silectone 100 Tablet contains spironolactone, which is a short-acting diuretic prescribed for the treatment of resistant oedema (fluid overload) associated with pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage).
Silectone 100 Tablet is usually taken once a day in the morning, but some people should take it twice. If you take it twice daily, take the second dose 4 hours before going to bed. Taking it later than this may mean you have to wake up at night to pee. Even so, following the doctor's directions is essential for obtaining the maximum benefits of Silectone 100 Tablet.
If you forget to take a dose of Silectone 100 Tablet, take it as soon as you remember, unless it's after 6 p.m. In this case, skip the missed dose and take your next dose at the usual time the next day. Do not take two doses to make up for a forgotten dose.
Yes, Silectone 100 Tablet can be used to treat hypertension. It works by increasing the amount of urine passed out from the kidneys. This effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of future heart attack, stroke, or angina (chest pain).
No, Silectone 100 Tablet is not intended for weight loss. However, it might help reduce weight related to fluid retention, especially in women with bloating and swelling due to PMS. Even so, do not use this medication on your own without consulting your doctor.
Here are some lifestyle changes you should consider while taking Silectone 100 Tablet such as:•Stay hydrated by drinking plenty of water.•Engage in moderate exercise like walking or swimming.•Get enough sleep.•Manage stress through relaxation techniques like yoga or meditation.•Limit your intake of potassium-rich foods like bananas, spinach, and potatoes.•Avoid salt substitutes containing potassium.•Avoid alcohol and caffeine, as they can increase dehydration.
Silectone 100 Tablet does not affect any type of contraception, including the combined pill and emergency contraception.
No, usually, it does not impact the kidney. Silectone 100 Tablet may reduce proteinuria and retard renal progression in chronic kidney disease patients.
Swallow the tablet whole with a drink of water. Do not chew it. Take Silectone 100 Tablet with a meal to help reduce side effects such as feeling sick. Follow doctor recommendations for dose and duration.
Common side effects of Silectone 100 Tablet may include low blood pressure (hypotension), dehydration, dizziness, electrolyte disturbances (potassium and sodium), increased creatinine levels in the blood, headache, nausea, and breast enlargement in males. Most of these side effects of Silectone 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Yes, Silectone 100 Tablet may interact with certain medications such as blood pressure-lowering pills, anti-epilepsy medicines, immune-suppressing drugs, anti-depression medicines and so on. So, do not take any other medication with Silectone 100 Tablet unless recommended by the doctor.
Before taking the Silectone 100 Tablet, let your doctor know about all your medical conditions, sensitivities, and medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
If prescribed, you can take Silectone 100 Tablet for a long time. Your doctor may perform specific blood tests during the treatment to ensure that the electrolytes in your blood, such as potassium, are correctly balanced.
Silectone 100 Tablet can make some people feel dizzy or tired, especially when they first start taking it or after taking a more significant dose. If this happens, do not drive a car or ride a bike until you feel better.
You are recommended not to consume alcohol along with Silectone 100 Tablet to avoid unpleasant side effects.

Manufacturer/Marketer address

B-117, Okhla Industrial Area, Phase I, New Delhi 110020
Other Info - SI26425

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