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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST

Signcold Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also shrinks the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Prescription drug

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Manufacturer/Marketer

Sign Pharma

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Signcold Syrup

Signcold Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs or talks.

Signcold Syrup is a combination of three drugs, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine (decongestant) and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that works by shrinking the blood vessels in the nasal passage. Thus, it provides relief from congestion and decreases excess mucus production. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergies such as sneezing, running nose, watery eyes, itching, swelling, and nasal congestion.

Take Signcold Syrup as prescribed. Your doctor will recommend you how often you take Signcold Syrup based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty in falling or staying asleep), blurred vision, constipation and dry mouth. Most of these side effects of Signcold Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Signcold Syrup or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Signcold Syrup. Do not use Signcold Syrup in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Signcold Syrup is not recommended for children below 4 years. Please do not take more than the prescribed dose of Signcold Syrup as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Signcold Syrup.

Uses of Signcold Syrup

Treatment of Common cold and allergies.

Medicinal Benefits

Signcold Syrup is a combination of three drugs: Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine belongs to the class of decongestants that work by contracting and narrowing the blood vessels. Thus, it provides relief from congestion and decreases mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Directions for Use

Take the medicine with or without food as advised by a doctor. Swallow it whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Signcold Syrup

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Constipation
  • Dry mouth

Drug Warnings

If you are allergic to Signcold Syrup or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Signcold Syrup. Do not use Signcold Syrup in breastfeeding mothers without doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Signcold Syrup is not recommended for children below 4 years. Please do not take more than the prescribed dose of Signcold Syrup as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Signcold Syrup.

Drug Interactions

Drug-Drug Interaction: Signcold Syrup may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, escitalopram), anticonvulsants (clonazepam), antianxiety drug (alprazolam), muscle relaxants (cyclobenzaprine), cough suppressants (dextromethorphan), bronchodilator (albuterol), sleeping agent (ramelteon), pain and fever medicines (paracetamol), pain killers (ibuprofen).

Drug-Food Interaction: Avoid intake of Signcold Syrup with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with Signcold Syrup as it may as it may increase the risk of liver damage and cause increased drowsiness, dizziness, and difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Signcold Syrup.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • ESCITALOPRAM
  • CLONAZEPAM
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • DEXTROMETHORPHAN
  • ALBUTEROL
  • PARACETAMOL
  • IBUPROFEN
  • RAMELTEON

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.

  • Drink plenty of fluids to avoid dehydration.

  • Gargle with salt water for relief from sore throat.

  • Avoid consumption of alcohol with Signcold Syrup as it may cause tiredness, drowsiness or lack of concentration.

Special Advise

  • Do not give Signcold Syrup to children below 4 years of age.
  • Do not take Signcold Syrup for longer than 7 days in a row (for adults) and 5 days (for the children above 4 years).
  • If you have allergic skin reactions like skin redness o rash that spreads and causes blistering and peeling, immediately contact a doctor.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

Allergies: These occur when foreign elements which cause allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger, 'histamines, ' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.

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Alcohol

Unsafe

Avoid consumption of alcohol with Signcold Syrup as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Signcold Syrup.

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Pregnancy

Caution

The safety of Signcold Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Caution

Signcold Syrup may be excreted in breast milk, and cause harm to the baby. Besides this, Signcold Syrup may also slow milk's production, so it is better to contact a doctor before a lactating mother takes it.

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Driving

Caution

Signcold Syrup may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Signcold Syrup.

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Liver

Caution

Take Signcold Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Signcold Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Signcold Syrup is not recommended for children below 4 years of age. However, please consult a doctor before giving Signcold Syrup to children.

Country of origin

India
Other Info - SIG0120

Author Details

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FAQs

Signcold Syrup is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
Signcold Syrup contains Paracetamol, Phenylephrine and Chlorpheniramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Yes, Signcold Syrup contains paracetamol which acts as mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
No, you are not recommended to consume alcohol with Signcold Syrup as it may increase the risk of liver damage and cause increased drowsiness, dizziness and lack of concentration.
Signcold Syrup is excreted in breast milk and may affect the health of baby. Therefore, if you are breastfeeding, please inform your doctor before taking Signcold Syrup so that the doctor may prescribe Signcold Syrup if the benefits are greater than risks.
Yes, Signcold Syrup may cause drowsiness. It is not necessary for everyone taking Signcold Syrup to experience this side effect. Therefore, avoid driving or operate heavy machinery if you feel drowsy after taking Signcold Syrup.
No, you are not recommended to take Signcold Syrup with Cetirizine as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness and difficulty in concentrating. However, please consult a doctor before taking Signcold Syrup with other medicines.
No, you are not recommended to stop taking Signcold Syrup without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Signcold Syrup for as long as your doctor has prescribed it, and if you experience any difficulty while taking Signcold Syrup, please consult your doctor.
Do not use Signcold Syrup if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Signcold Syrup if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Signcold Syrup may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, immediately contact your doctor and stop taking Signcold Syrup.

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