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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Serta 25 Tablet is used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). It contains Sertraline, which increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic. Some people may experience side effects such as drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

SERTRALINE-25MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Serta 25 Tablet

Serta 25 Tablet belongs to a class of antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs) used in the treatment of depression, post-traumatic stress disorder (PTSD), social anxiety disorder, panic disorder and obsessive-compulsive disorder (OCD). Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do. OCD is a mental disorder with symptoms such as excessive thoughts or ideas (obsessions), leading to repetitive behaviours (compulsions). Panic disorder is linked to anxiety with sudden feelings of fear when there is no danger in reality. PTSD is a mental condition that occurs after experiencing a very emotional or terrifying event and has symptoms similar to anxiety and depression. Social anxiety disorder (social phobia) is associated with intense anxiety or distress in social situations.

Serta 25 Tablet contains Sertraline that works by inhibiting the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Serta 25 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Take Serta 25 Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not break, crush or chew it. Your doctor will advise you how often you take Serta 25 Tablet based on your medical condition. Some people may experience drowsiness, dizziness, insomnia (difficulty in sleeping), dry mouth, nausea, headache, diarrhoea, tiredness or ejaculation failure. Most of these side effects of Serta 25 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Serta 25 Tablet or any other medicines, please tell your doctor. Serta 25 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and not treat any other conditions in children below 18 years of age. Serta 25 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Serta 25 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serta 25 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Serta 25 Tablet , inform your doctor as they may worsen in the initial days of taking Serta 25 Tablet . Do not take Serta 25 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids as it may cause severe adverse effects.

Uses of Serta 25 Tablet

Treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, Obsessive-compulsive disorder (OCD).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Serta 25 Tablet contains Sertraline, an antidepressant that inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Serta 25 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

How Serta 25 Tablet Works

Serta 25 Tablet contains Sertraline that works by inhibiting the reabsorption of released serotonin back into the nerve cells. Thus, it increases serotonin activity (chemical messenger) in the brain that is involved in regulating mood, behaviour, and emotions. Thereby, Serta 25 Tablet helps relieve depression, lighten the mood and relieve anxiety symptoms such as fear and panic.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Serta 25 Tablet

  • Drowsiness

  • Dizziness
  • Insomnia (sleeplessness)
  • Dry mouth
  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Ejaculation failure

What if I have taken an overdose of Serta 25 Tablet

Do not take more than the prescribed dose of Serta 25 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

If you are allergic to Serta 25 Tablet or any other medicines, please tell your doctor. Serta 25 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years and does not treat any other conditions in children below 18 years of age. Serta 25 Tablet is not recommended for use during pregnancy, especially in the last 3 months. It may cause a serious condition in the baby, such as persistent pulmonary hypertension of the newborn (PPHN), which causes the baby to appear bluish and breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy. Serta 25 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serta 25 Tablet should be used with caution in elderly patients as there is an increased risk of low sodium levels in the blood.  If you have any self-harming or suicidal thoughts before taking Serta 25 Tablet , inform your doctor as they may worsen in the initial days of taking Serta 25 Tablet . Do not take Serta 25 Tablet with monoamine oxidase inhibitors (MAOIs) such as moclobemide and methylene blue to treat depression and opioids pain killer as it may cause severe adverse effects. If you have diabetes, fits, bipolar disorder, bleeding disorders, glaucoma, severe diarrhoea, low sodium or potassium levels in the blood, neuroleptic malignant syndrome or serotonin syndrome (potentially life-threatening conditions), liver or heart problems, inform your doctor before taking Serta 25 Tablet . 

Drug-Drug Interactions

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SertralineTranylcypromine
Critical
SertralineIsocarboxazid
Critical

Drug-Drug Interactions

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SertralineTranylcypromine
Critical
How does the drug interact with Serta 25 Tablet 15's:
Taking Tranylcypromine and Serta 25 Tablet 15's may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine and Serta 25 Tablet 15's is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineIsocarboxazid
Critical
How does the drug interact with Serta 25 Tablet 15's:
Co-administration of Serta 25 Tablet 15's with Isocarboxazid can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Isocarboxazid with Serta 25 Tablet 15's there may be a possibility of interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineZiprasidone
Critical
How does the drug interact with Serta 25 Tablet 15's:
Co-administration of Serta 25 Tablet 15's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Serta 25 Tablet 15's with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SertralineThioridazine
Critical
How does the drug interact with Serta 25 Tablet 15's:
Co-administration of Thioridazine and Serta 25 Tablet 15's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine and Serta 25 Tablet 15's is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations -contact a doctor right away. Do not stop using any medications without a doctor's advice.
SertralineHalofantrine
Critical
How does the drug interact with Serta 25 Tablet 15's:
Coadministration of halofantrine and Serta 25 Tablet 15's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Serta 25 Tablet 15's and halofantrine, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineEliglustat
Critical
How does the drug interact with Serta 25 Tablet 15's:
Coadministration of Eliglustat and Serta 25 Tablet 15's may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Eliglustat and Serta 25 Tablet 15's, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineProcarbazine
Critical
How does the drug interact with Serta 25 Tablet 15's:
When Procarbazine is taken with Serta 25 Tablet 15's, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Serta 25 Tablet 15's and Procarbazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineDronedarone
Critical
How does the drug interact with Serta 25 Tablet 15's:
Co-administration of Dronedarone and Serta 25 Tablet 15's may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dronedarone with Serta 25 Tablet 15's is not recommend, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
SertralineSelegiline
Critical
How does the drug interact with Serta 25 Tablet 15's:
Co-administration of Serta 25 Tablet 15's with Selegiline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selegiline with Serta 25 Tablet 15's together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
SertralineLinezolid
Critical
How does the drug interact with Serta 25 Tablet 15's:
When linezolid is taken with Serta 25 Tablet 15's, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Linezolid and Serta 25 Tablet 15's is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods as they may worsen anxiety. Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.

  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters.

  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.

  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Regularly attend therapy sessions.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Serta 25 Tablet Substitute

Substitutes safety advice
  • Zosert 25 Tablet 10's

    6.66per tablet
  • Daxid 25 Tablet 15's

    3.99per tablet
  • Serlift 25 Tablet 10's

    6.89per tablet
  • Sertima 25mg Tablet 10's

    by AYUR

    6.53per tablet
  • SRT 25 mg Tablet 15's

    5.55per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Serta 25 Tablet as it may increase the risk of drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Serta 25 Tablet is a Category C pregnancy drug and is not recommended for use during pregnancy especially in the last 3 months as it may cause a serious condition in the baby such as persistent pulmonary hypertension of the newborn (PPHN) which causes the baby to appear bluish and makes breathing faster. Therefore, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Serta 25 Tablet may be excreted in human milk. Please consult a doctor if you are a breastfeeding mother. Serta 25 Tablet is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Unsafe

Serta 25 Tablet may cause dizziness, drowsiness or impair thinking. Therefore, avoid driving if you experience any of these symptoms after taking Serta 25 Tablet .

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Liver

Caution

Take Serta 25 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

If you have any concerns regarding the use of Serta 25 Tablet in patients with kidney problems, please consult a doctor.

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Children

Caution

Serta 25 Tablet may be used only to treat Obsessive-compulsive disorder (OCD) in children aged 6 to 17 years. Serta 25 Tablet is not recommended to treat any other disorders in children below 18 years of age.

FAQs

Serta 25 Tablet used in the treatment of Depression, Post-traumatic stress disorder (PTSD), Social anxiety disorder, Panic disorder, and Obsessive-compulsive disorder (OCD).
Yes, Serta 25 Tablet may be used to treat a panic disorder by reducing fear. However, please consult a doctor before using the Serta 25 Tablet .
No, you are not recommended to take Serta 25 Tablet with opioids as co-administration of these medicines may cause adverse effects such as hallucinations, increased muscle tension, excessive sweating, fever, anxiety, involuntary, rhythmic contractions of muscles, including the muscles that control eye movement, tremor or even coma. However, before using Serta 25 Tablet with any other medicines, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.
Yes, Serta 25 Tablet may cause self-harming or suicidal thoughts, especially in patients aged less than 25 years or who have a history of self-harming thoughts. Therefore, please consult a doctor immediately if you experience any such thoughts while taking Serta 25 Tablet .
It takes about 2 weeks or longer, usually for Serta 25 Tablet to work. However, it is recommended to use Serta 25 Tablet for as long as your doctor has prescribed it for you.
Serta 25 Tablet may affect male fertility as it may reduce sperm quality. Therefore, please consult a doctor if you are planning to father a child.
Serta 25 Tablet should be used with caution in diabetic patients as it may alter blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Serta 25 Tablet , especially if you have diabetes, and the dose of diabetic medicines may be adjusted appropriately by your doctor.
Serta 25 Tablet contains Sertraline, which inhibits the reabsorption of released serotonin back into the nerve cells. Thus, it increases the serotonin (chemical messenger) activity in the brain that regulates mood, behaviour and emotions. Thereby, Serta 25 Tablet helps in relieving depression, lightening the mood and relieving anxiety symptoms such as fear and panic.
The side effects of Serta 25 Tablet include nausea, headache, diarrhoea, tiredness, drowsiness, dizziness and insomnia (difficulty sleeping). If these side effects persist or worsen, please consult your doctor.
You are recommended to take Serta 25 Tablet for as long as it is prescribed by your doctor, which may be for several months. Do not stop taking Serta 25 Tablet before the advised time as it may cause depression to recur.
Take Serta 25 Tablet as advised by your doctor. It can be taken with or without food at any time of the day and is usually taken once a day. Take it as per your convenience but preferably at the same time every day. Some people should take it in the morning who have sleep difficulty after taking Serta 25 Tablet . Whereas, some take it at night to minimize the side effects of vomiting and nausea.
Yes, sleepiness is a common side effect of Serta 25 Tablet . Avoid driving or using heavy machinery if you feel sleepy, dizzy, or tired after taking Serta 25 Tablet . This usually occurs within the first few days and weeks after starting Serta 25 Tablet , which may disappear after 2-3 months.
Serta 25 Tablet increases the serotonin levels which is an important chemical and a neurotransmitter. This helps to improve and regulate mood, resulting in an improvement in the anxiety symptoms.
No, do not stop taking Serta 25 Tablet without consulting your doctor as discontinuing suddenly may cause withdrawal symptoms. Therefore, it is important to reduce the dose gradually with time (over several weeks or months).
The withdrawal symptoms of Serta 25 Tablet include numbness or tingling in the hands or feet, dizziness, nausea, trouble sleeping, headaches, feeling agitated or anxious, and shaking. However, these symptoms are usually mild to moderate and disappear 1-2 weeks after stopping Serta 25 Tablet .
The symptoms of Serta 25 Tablet overdose include fever, nausea, vomiting, dizziness, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include heart problems, fainting, delirium, and changes in blood pressure. If you experience such symptoms, contact your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102
Other Info - SER0017

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