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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST

Serenace Injection 1 ml is used to treat Schizophrenia. It contains Haloperidol, which works by blocking the dopamine receptors in the brain, preventing their overactivity. Thus, it controls psychotic illnesses and improves disturbed thoughts, behaviour, and feelings in mental conditions such as Schizophrenia. Therefore, Serenace Injection 1 ml improves overall behaviour and thoughts and helps people have a better social life and comfortably do daily activities. Additionally, this mediation is used to control motor and speech tics in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

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Prescription drug

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Synonym

HALOPERIDOL DECANOATE

Composition

HALOPERIDOL-5MG

Manufacturer/Marketer

RPG Life Sciences Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Serenace Injection 1 ml

Serenace Injection 1 ml is used in the treatment of schizophrenia. Also, it is used to control motor and speech tics of Tourette’s disorder. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). 

Serenace Injection 1 ml contains Haloperidol, which blocks the dopamine receptors in the brain, preventing its overactivity, thereby controlling psychotic illnesses and improving disturbed thoughts, behaviour and feelings in mental conditions such as schizophrenia.

Serenace Injection 1 ml will be administered by a healthcare professional; do not self-administer. Sometimes, Serenace Injection 1 ml may cause common side effects such as drowsiness, tremors, neck stiffness, nausea or vomiting, increased salivation, and weight gain. Most of these side effects of Serenace Injection 1 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Haloperidol or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before receiving Serenace Injection 1 ml . Serenace Injection 1 ml is not recommended for children. Dose adjustment may be required for elderly or physically unwell patients. Avoid driving until your doctor says it is safe, as Serenace Injection 1 ml may impair your physical or mental abilities required for driving. You are recommended to avoid alcohol consumption with Serenace Injection 1 ml as it may increase the effects of alcohol.

Uses of Serenace Injection 1 ml

Treatment of Schizophrenia

Medicinal Benefits

Serenace Injection 1 ml contains Haloperidol, an antipsychotic used in the treatment of schizophrenia. It works by blocking the dopamine receptors in the brain, preventing its overactivity, thereby controlling psychotic illnesses and improving disturbed thoughts, behaviour and feelings in mental conditions such as schizophrenia. Thus, Serenace Injection 1 ml improves overall behaviour and thoughts and helps people have a better social life and comfortably do daily activities. Additionally, Serenace Injection 1 ml is used to control motor and speech tics in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements).

Directions for Use

Serenace Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Serenace Injection 1 ml

  • Drowsiness
  • Tremors
  • Neck stiffness
  • Nausea or vomiting
  • Increased salivation
  • Weight gain

Drug Warnings

Please tell your doctor if you are allergic to Haloperidol or other medicines. If you are pregnant or breastfeeding, inform your doctor before receiving Serenace Injection 1 ml . Serenace Injection 1 ml is not recommended for children. Dose adjustment may be required for elderly or physically unwell patients. Avoid driving until your doctor says it is safe, as Serenace Injection 1 ml may impair your physical or mental abilities required for driving. You are recommended to avoid alcohol consumption with Serenace Injection 1 ml as it may increase the effects of alcohol. If you have Parkinson’s disease, avoid receiving Serenace Injection 1 ml . If you suffer from electrolyte imbalance, inform your doctor before receiving Serenace Injection 1 ml .

Drug Interactions

Drug-Drug Interaction: If you are taking medicines used to control mood swings or depression (nefazodone, venlafaxine, buspirone, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium, chlorpromazine, citalopram, escitalopram, alprazolam), antipsychotics, antifungals (itraconazole, ketoconazole, pentamidine), medicines known to cause electrolyte imbalance, strong painkillers or tranquillisers, medicines used to treat irregular heartbeat (amiodarone, sotalol, quinidine, disopyramide), antibiotics (rifampicin, erythromycin, moxifloxacin, levofloxacin), medicines for Parkinson’s disease (levodopa), anticonvulsants (carbamazepine, phenobarbital), antimalarial (halofantrine), gastrointestinal medicines (dolasetron), anticancer drugs (toremifene, vandetanib), or HIV drugs (ritonavir), inform your doctor before receiving Serenace Injection 1 ml .

Drug-Food Interaction: Inform your doctor if you are taking St. John's Wort (herbal medicine used to treat depression).

Drug-Disease Interaction: Avoid receiving Serenace Injection 1 ml if you have severe depression, severe drowsiness due to illness, medicine or alcohol, Parkinson’s disease, spastic diseases, Lewy body dementia, or progressive supranuclear palsy (brain disorder). If you have dementia-related psychosis, have ever had bleeding in the brain, heart problems, low blood pressure, QT prolongation (rare heart disorder), tardive dyskinesia (uncontrolled movements of the mouth, tongue, cheeks or jaw), hyperthyroidism (very active thyroid gland), extremely high blood pressure, a sudden increase in body temperature, severe convulsions, liver disease, have or ever had fits, blood clots, inform your doctor before receiving Serenace Injection 1 ml .

Drug-Drug Interactions Checker List

  • NEFAZODONE
  • VENLAFAXINE
  • BUSPIRONE
  • FLUVOXAMINE
  • FLUOXETINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • CHLORPROMAZINE
  • CITALOPRAM
  • ESCITALOPRAM
  • ALPRAZOLAM
  • ITRACONAZOLE
  • KETOCONAZOLE
  • PENTAMIDINE
  • AMIODARONE
  • SOTALOL
  • QUINIDINE
  • DISOPYRAMIDE
  • RIFAMPICIN
  • ERYTHROMYCIN
  • MOXIFLOXACIN
  • LEVOFLOXACIN
  • LEVODOPA
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • HALOFANTRINE
  • DOLASETRON
  • TOREMIFENE
  • VANDETANIB
  • RITONAVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Serenace Injection 1 ml .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down on sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Exercise regularly and maintain a stable weight as Serenace Injection 1 ml may cause weight gain.
  • Avoid the consumption of alcohol as it may increase drowsiness.

Special Advise

  • Elderly patients (more than 65 years of age) with dementia-related psychosis treated with Serenace Injection 1 ml can be at an increased risk of death. 
  • Serenace Injection 1 ml is not approved for the treatment of patients with dementia-related psychosis.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption with Serenace Injection 1 ml as it may increase the effects of alcohol and also cause hypotension (low blood pressure).

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Pregnancy

Consult your doctor

Limited data is available on the effect of Serenace Injection 1 ml in pregnancy. Hence, if you are pregnant or planning for pregnancy, inform your doctor before receiving Serenace Injection 1 ml . Your doctor may prescribe this medicine only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Serenace Injection 1 ml if used in breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Serenace Injection 1 ml . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Serenace Injection 1 ml may impair your physical or mental abilities required for driving. Therefore, avoid driving until your doctor says it is safe.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Serenace Injection 1 ml . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Serenace Injection 1 ml . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Serenace Injection 1 ml is not recommended for children as safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai ? 400 030. Maharashtra, INDIA
Other Info - SER0004

Author Details

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FAQs

Serenace Injection 1 ml is used to treat Schizophrenia.
Serenace Injection 1 ml contains Haloperidol, an antipsychotic that works by blocking the dopamine receptors in the brain, preventing its overactivity, thereby controlling psychotic illnesses and improving disturbed thoughts, behaviour and feelings in mental conditions such as schizophrenia.
Serenace Injection 1 ml may cause weight gain in some patients. However, to avoid gaining weight while receiving Serenace Injection 1 ml , you are advised to exercise regularly and avoid high-calorie drinks. Instead, take non-alcoholic drinks, herbal tea and lemon water.
Dose adjustment may be needed for elderly patients. Serenace Injection 1 ml is not recommended for elderly patients with dementia-related psychosis as it may increase the risk of death. Therefore, it is advised to inform your doctor if you have dementia before receiving Serenace Injection 1 ml .

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