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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Septran Oral Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). It contains Trimethoprim and Sulfamethoxazole, which stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections. In some cases, you may experience certain common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Koye Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Septran Oral Suspension

Septran Oral Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Septran Oral Suspension does not work against infections caused by the virus, including cold and flu. 

Septran Oral Suspension is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Oral Suspension stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Your doctor will decide the dose and duration of Septran Oral Suspension based on your condition and the severity of the infection. In some cases, you may experience certain common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Septran Oral Suspension, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Septran Oral Suspension on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Septran Oral Suspension if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Septran Oral Suspension is not recommended for children below 12 years.

Uses of Septran Oral Suspension

Treatment of Bacterial infections.

Directions for Use

Swallow Septran Oral Suspension as a whole with water; do not crush or chew it.

Medicinal Benefits

Septran Oral Suspension belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Septran Oral Suspension is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Oral Suspension kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Septran Oral Suspension is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

How Septran Oral Suspension Works

Septran Oral Suspension is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Septran Oral Suspension stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Septran Oral Suspension

  • High levels of potassium in the blood
  • Palpitations (abnormal heartbeats)
  • Thrush or candidiasis (fungal infection)
  • Headache
  • Nausea
  • Diarrhoea
  • Skin rashes

What if I have taken an overdose of Septran Oral Suspension

Do not take more than the prescribed dose of Septran Oral Suspension as it may cause overdose. The symptoms of overdose include headache, dizziness, nausea, vomiting, confusion, loss of appetite, drowsiness, or mental depression. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Septran Oral Suspension if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Septran Oral Suspension if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Septran Oral Suspension to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Drug-Drug Interactions

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TrimipramineZiprasidone
Critical
TrimipramineTranylcypromine
Critical

Drug-Drug Interactions

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TrimipramineZiprasidone
Critical
How does the drug interact with Septran Oral Suspension 60 ml:
Co-administration of Septran Oral Suspension 60 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Septran Oral Suspension 60 ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TrimipramineTranylcypromine
Critical
How does the drug interact with Septran Oral Suspension 60 ml:
Taking Tranylcypromine with Septran Oral Suspension 60 ml can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Septran Oral Suspension 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TrimipramineSafinamide
Critical
How does the drug interact with Septran Oral Suspension 60 ml:
Taking Safinamide with Septran Oral Suspension 60 ml can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Septran Oral Suspension 60 ml is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
sulfamethoxazoleClozapine
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
The combined use of Septran Oral Suspension 60 ml and clozapine may increase the risk or severity of toxicity.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Septran Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
TrimipramineFlumazenil
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
Combining flumazenil together with Septran Oral Suspension 60 ml can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although taking Flumazenil and Septran Oral Suspension 60 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience irregular heartbeat, chest tightness, blurred vision, nausea and seizures contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrimipramineHaloperidol
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
Using haloperidol together with Septran Oral Suspension 60 ml can affect the rhythm of your heart.

How to manage the interaction:
Co-administration of Septran Oral Suspension 60 ml and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like tiredness, dizziness, fainting, confusion, tremor, difficulty breathing, an irregular heartbeat, dry mouth, visual disturbances, urinary retention, dizziness, constipation, and seizures, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TrimipramineSumatriptan
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
Using Septran Oral Suspension 60 ml together with Sumatriptan might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction between Sumatriptan and Septran Oral Suspension 60 ml, you can take these medicines together if prescribed by your doctor. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
TrimipramineEphedrine
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
Co-administration of Ephedrine and Septran Oral Suspension 60 ml together may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ephedrine and Septran Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. It's important to maintain your blood pressure. Do not stop using any medications without talking to a doctor.
TrimipramineMirtazapine
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
Using Septran Oral Suspension 60 ml together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
There may be a possibility of interaction between Mirtazapine and Septran Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs like feeling confused, seeing or hearing things that aren't there, having a seizure, a fast heartbeat, a high temperature, sweating a lot, shaking, having trouble seeing clearly, muscle spasms or stiffness, difficulty moving, stomach pain, feeling sick, throwing up, or having diarrhea, make sure to call a doctor right away. They will be able to help you." Do not discontinue any medications without consulting a doctor.
TrimipramineDisopyramide
Severe
How does the drug interact with Septran Oral Suspension 60 ml:
The combined use of Septran Oral Suspension 60 ml and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Septran Oral Suspension 60 ml and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION

Septran Oral Suspension Substitute

Substitutes safety advice
  • Bactrim Suspension 30 ml

    0.59per tablet
  • Septran Oral Suspension 50 ml

    by AYUR

    0.32per tablet
  • Cumide Suspension 50 ml

    0.36per tablet
  • Vostrim Suspension

    0.21per tablet
  • Btrim Oral Suspension

    0.23per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while taking Septran Oral Suspension to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Caution

Please consult your doctor before taking Septran Oral Suspension if you are pregnant. Your doctor will prescribe Septran Oral Suspension only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Septran Oral Suspension only if the benefits outweigh the risks.

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Driving

Caution

It is unknown whether Septran Oral Suspension affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed.

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Liver

Caution

Please consult your doctor before taking Septran Oral Suspension if you have liver impairment/liver disease. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Septran Oral Suspension to be taken with caution, especially if you have a history of kidney impairment/kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Septran Oral Suspension is not recommended for children below 12 years.

FAQs

Septran Oral Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).
Septran Oral Suspension is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Septran Oral Suspension kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.
Septran Oral Suspension causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
Diarrhoea might be a side-effect of Septran Oral Suspension. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Septran Oral Suspension and consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Septran Oral Suspension even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Septran Oral Suspension for as long as your doctor has prescribed to treat your condition effectually.
Do not take Septran Oral Suspension on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Septran Oral Suspension may affect certain laboratory test results. Inform the person doing the tests that you are taking Septran Oral Suspension.
Septran Oral Suspension may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Septran Oral Suspension.
You can take Septran Oral Suspension with or without as advised by your doctor. Take Septran Oral Suspension preferably with food to avoid nausea or diarrhoea.
No, Septran Oral Suspension is not an addiction causing medicine. But the dose and duration should be followed as prescribed by your doctor.
Yes, Septran Oral Suspension can be used for urinary tract infection as Septran Oral Suspension is used to prevent infections caused by bacteria.
Pimples are caused due to various reasons. Therefore, please consult your doctor before taking Septran Oral Suspension. If you have any concerns regarding acne, discuss with your doctor.
Yes, Septran Oral Suspension is a stronger antibiotic. It contains two antibiotics namely, Sulfamethoxazole and Trimethoprim.
Septran Oral Suspension can cause side effects such as high levels of potassium in your blood, which can cause abnormal heart beats. Also, it may cause fungal infections like thrush or candidiasis which can affect mouth or vagina and other common side effects like headache, nausea, diarrhoea and skin rashes. If these effects worsen or persist, consult your doctor.
Yes, Septran Oral Suspension is safe to use in most patients. However consult your doctor if you experience any side effects like nausea, vomiting, skin rash, allergic reaction.
Yes, Septran Oral Suspension can cause nausea and vomiting. If these persist or worsen, consult your doctor.
Septran Oral Suspension is contraindicated in patients who have a history of drug-induced immune thrombocytopenia from using trimethoprim and/or sulfonamides, who have a known hypersensitivity to these medications, or who have megaloblastic anemia from a folate deficiencies and in patients with severe renal insufficiency or obvious liver impairment.
Avoid spicy, acidic, and greasy foods while taking Septran Oral Suspension as they may increase your risk of side effects such upset stomach and diarrhoea. Also, Septran Oral Suspension can interact with alcohol. It's best to avoid drinking alcohol while taking Septran Oral Suspension.
Yes, Septran Oral Suspension expires. The expiry date can be found on the packaging.
No, do not stop taking Septran Oral Suspension without first consulting your doctor. Complete the full course of treatment even if you feel better as you may notice an improvement in your symptoms before the infection is cured completely.
If you miss a dose of Septran Oral Suspension, do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.
If you don't feel better after completing the full course of treatment with Septran Oral Suspension, inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Septran Oral Suspension.
Septran Oral Suspension should be used in children above 12 years of age if advised by a doctor.
Avoid taking Septran Oral Suspension if you are allergic to Sulfamethoxazole, Trimethoprim or any other ingredients of Septran Oral Suspension. If you have severe liver or kidney problems, or have ever had thrombocytopenia (blood problem causing bleeding or bruises) or have porphyria (a rare blood problem), inform your doctor before taking Septran Oral Suspension.
Take Septran Oral Suspension as advised by your doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose. Swallow it as whole with a glass of water. Do not crush or chew it.
Store the Septran Oral Suspension in the original package at room temperature. Keep it out of the reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India.
Other Info - SEP0013

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