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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:18 PM IST
Seimther Oral Suspension is used to treat and prevent malaria. It contains Artemether and Lumefantrine which interfere with Plasmodium parasite's growth in the red blood cells of the human body. It is a combination medicine used to treat non-severe malaria caused by a parasite called Plasmodium falciparum. It may cause common side effects such as headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Seimther Oral Suspension

Seimther Oral Suspension belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. Malaria is a disease caused by a plasmodium parasite, transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start in 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

Seimther Oral Suspension contains two medicines, namely: Artemether and Lumefantrine. These are anti-malarial drugs that interfere with Plasmodium parasite's growth in the red blood cells of the human body. Seimther Oral Suspension is a combination that is used to treat non-severe malaria caused by a parasite called 'Plasmodium falciparum,' other Plasmodium species. It works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether is known to reduce parasite biomass and Lumefantrine eliminates residual parasites.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Seimther Oral Suspension include headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before using Seimther Oral Suspension, inform your doctor if you recently used any prescription and non-prescription medications, including other anti-malarial or antibiotic drugs. Let your doctor know if you are allergic to Seimther Oral Suspension or its components. Inform your doctor if you have any liver or kidney problems, severe heart diseases and electrolyte imbalance. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoiding alcohol is recommended to rule out any possibility of side effects.

Uses of Seimther Oral Suspension

Treatment of Malaria.

Medicinal Benefits

Seimther Oral Suspension contains two anti-malarial drugs, namely: Artemether and Lumefantrine. It is a combination that treats non-severe malaria caused by a parasite called 'Plasmodium falciparum', other Plasmodium species. It interferes with the growth of Plasmodium parasites in the red blood cells of the human body. Seimther Oral Suspension works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether reduces parasite biomass and Lumefantrine eliminates residual parasites.

Directions for Use

Tablet: Swallow it as a whole with a glass of water, do not chew or break the tablet.For patients like infants and children who cannot swallow the tablets, crush the tablet and mix it with 1 to 2 teaspoons of water in a clean container and administer it. Rinse the container with more water and swallow the contents. You can also give the crushed tablet preparation with food/drink like milk, formula, pudding, broth and porridge.Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Seimther Oral Suspension

  • Headache
  • Dizziness
  • Loss of appetite
  • Weakness
  • Fever
  • Chills
  • Tiredness
  • Muscle/joint pain
  • Nausea
  • Vomiting
  • Abdominal pain
  • Cough
  • Trouble sleeping

Drug Warnings

Let your doctor know if you use any antibiotic drugs or have recently undergone treatment with other anti-malarial drugs. Brief your medical history to the doctor if you have any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. It is essential to inform your doctor if you have hypokalemia (low potassium levels) or hypomagnesemia (low magnesium levels) before starting Seimther Oral Suspension. Seimther Oral Suspension may affect QT prolongation that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram), and a family history of heart diseases. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before starting Seimther Oral Suspension. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness or drowsiness.

Drug Interactions

Drug-Drug Interaction: Seimther Oral Suspension may interact with other anti-malarial drugs (mefloquine, quinine, quinidine), drugs treating abnormal heart rhythms (flecainide, amiodarone, sotalol, procainamide, disopyramide), antipsychotics (pimozide, ziprasidone), macrolide antibiotics (erythromycin), antibiotics (ciprofloxacin, moxifloxacin, rifabutin, rifampin), fits medicines (carbamazepine, phenobarbital, phenytoin), antifungals (ketoconazole, itraconazole), HIV drugs (delavirdine, efavirenz, nelfinavir, ritonavir), antidepressants (clomipramine, amitriptyline, imipramine), blood pressure drugs (metoprolol), depression medicines (St. John's wort) and birth control pills.

Drug-Food Interaction: Avoiding alcohol may improve the side effects of Seimther Oral Suspension. Grapefruit juice may affect the efficacy of Seimther Oral Suspension; hence please avoid it during treatment with Seimther Oral Suspension.

Drug-Disease Interaction: Before using Seimther Oral Suspension, let your doctor know if have any heart diseases, liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases, and electrolyte imbalance.

Drug-Drug Interactions Checker List

  • MEFLOQUINE
  • QUININE
  • QUINIDINE
  • FLECAINIDE
  • AMIODARONE
  • SOTALOL
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • PIMOZIDE
  • ZIPRASIDONE
  • ERYTHROMYCIN
  • CIPROFLOXACIN
  • MOXIFLOXACIN
  • RIFABUTIN
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • DELAVIRDINE
  • EFAVIRENZ
  • NELFINAVIR
  • RITONAVIR
  • CLOMIPRAMINE
  • AMITRIPTYLINE
  • IMIPRAMINE
  • METOPROLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take nutritious food, including fresh fruits and vegetables that help in recovering from malarial fever.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices and coconut water.
  • Include high fibre foods like green leafy vegetables and fruits to aid digestion.
  • Take proper rest to help your body relax and heal faster.
  • Avoid or limit the intake of alcohol and caffeine.

Special Advise

  • Let your doctor know that you are taking Seimther Oral Suspension if you are undergoing any medical tests.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Seimther Oral Suspension may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. 

Disease/Condition Glossary

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This is a common disease in countries like Africa, South America and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Malaria symptoms usually start in 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

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Alcohol

Caution

Avoid alcohol while using Seimther Oral Suspension since it can worsen your side effects.

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Pregnancy

Caution

Seimther Oral Suspension is not recommended during the first three months of pregnancy. Your doctor may recommend other alternative medication. Please seek medical advice if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Seimther Oral Suspension is not recommended during breastfeeding. Once you have completed the course, you should wait at least one week before starting to breastfeed again. Please consult your doctor before taking Seimther Oral Suspension.

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Driving

Caution

Seimther Oral Suspension may make you feel sleepy, dizzy or generally weak. In such cases, do not drive or operate machinery.

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Liver

Caution

Close monitoring of patients with liver diseases while being treated with Seimther Oral Suspension is required. Let your doctor know if you have any history of liver diseases before using Seimther Oral Suspension.

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Kidney

Caution

Therapy with Seimther Oral Suspension is to be cautiously administered in patients with renal impairment. Let your doctor know if you have any history of kidney diseases before using Seimther Oral Suspension.

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Children

Safe if prescribed

Your doctor will decide the dose based on your child's age and bodyweight.

Country of origin

India
Other Info - SE67297

Author Details

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FAQs

Seimther Oral Suspension belongs to the class of anti-malarial drugs, used to treat and prevent malaria.
Seimther Oral Suspension contains a combination of anti-malarial drugs, Artemether and Lumefantrine. It treats malaria by interfering with Plasmodium parasite's growth in the red blood cells of the human body.
Seimther Oral Suspension may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.
Seimther Oral Suspension is not recommended in cases of any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. Also, let your doctor know if you have recently undergone treatment with other anti-malarial drugs.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Seimther Oral Suspension should be swallowed as a whole with water; do not crush or chew it.
Seimther Oral Suspension is not recommended during the first three months of pregnancy. Your doctor may recommend other alternative medication. Please seek medical advice if you are pregnant or planning to conceive.
Seimther Oral Suspension is contraindicated if you are allergic to any of its components.
Store Seimther Oral Suspension at room temperature, in a dry place. Keep it out of sight and reach of children.
Seimther Oral Suspension should be taken with food as it aids in better absorption of the medicine.
Take another dose of Seimther Oral Suspension if you have vomited within 1-2 hours of taking the medicine.
Seimther Oral Suspension may cause side effects like headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Do not discontinue Seimther Oral Suspension without consulting your doctor. To treat your condition effectively, keep taking Seimther Oral Suspension for the prescribed duration.

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