Scabizine 1% Lotion belongs to a class of medications called ‘antiparasitic drugs’ used to treat scabies and pediculosis. Scabies is a skin infection caused by mites. Pediculosis is the infestation of lice in the hairy parts of the body, especially the scalp. These conditions are contagious and spread from one person to another with direct contact. Symptoms include rashes and persistent itching in the infected area, which worsens in the night-time.

Scabizine 1% Lotion contains ‘Gamma benzene hexachloride’ (also called Lindane). It is an antiparasite and acts by killing mites and lice and their eggs by penetrating the skin. It is recommended to use only if you have scabies and pediculosis. Scabizine 1% Lotion doesn't help to prevent these conditions.

Scabizine 1% Lotion is only for external use. You should use Scabizine 1% Lotion exactly as prescribed by the doctor. Scabizine 1% Lotion may cause side effects such as dryness, rash, itching, or burning sensation in the treated area. Most of these side effects of Scabizine 1% Lotion do not require medical attention and gradually resolve over time. However, if the side effects persist or get worse, please consult your doctor immediately.

It is not recommended to use Scabizine 1% Lotion if you are allergic to any of its contents. Scabizine 1% Lotion should not be used for people who have had any seizure episodes (fits). Inform your doctor if you have. Before taking Scabizine 1% Lotion, inform your doctor if you have AIDS/HIV or liver cirrhosis, alcoholism, history of head injury, spinal cord, or brain tumor. It is not recommended for premature babies, pregnant women, breastfeeding mothers, and elderly people. It is not known whether the Scabizine 1% Lotion can interact with alcohol. So, please consult your doctor. Scabizine 1% Lotion may not affect your ability to drive.

Scabizine 1% Lotion is an antiparasitic drug used to treat scabies (a skin infection) and pediculosis (lice infestation). Scabizine 1% Lotion kills scabies mites and their eggs by going through the skin. Scabizine 1% Lotion in shampoo form is used to treat head lice. Scabizine 1% Lotion is used to treat scabies and pediculosis in patients for whom other medicines did not work or cannot be given other safer medicines.

• Dry skin
• Skin rash
• Itching
• Burning sensation of skin

Do not use Scabizine 1% Lotion in premature infants due to the increased risk of skin permeability. If you have uncontrolled fits, inform your doctor before using Scabizine 1% Lotion. It may be absorbed by the whole body and cause central nervous system toxicity resulting in disorientation, dizziness, and fits. You are advised to wash Scabizine 1% Lotion from the body completely after 8-12 hours using warm water as leaving it on the skin for a prolonged time may lead to fatal effects. There may be skin itching for a few weeks even after using Scabizine 1% Lotion. However, if the itching worsens, please consult a doctor.  Do not use Scabizine 1% Lotion to treat the second attack of scabies that comes immediately after the first episode as using it more than one time can lead to fatal effects.

Drug-Drug Interactions: Scabizine 1% Lotion may interact with antipsychotics (haloperidol), bronchodilators (theophylline), antibiotics (imipenem, penicillins), and quinolone antibiotics (ciprofloxacin, ofloxacin, and norfloxacin, etc.), an antidepressant (bupropion), immunosuppressants (cyclosporine, tacrolimus, and mycophenolate mofetil), antimalarial drugs (pyrimethamine and chloroquine), antituberculosis agent (isoniazid), pain killer (meperidine), muscle relaxant (methocarbamol), and radiographic contrast agents (iopamidol, iohexol).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Scabizine 1% Lotion should not be used in patients with uncontrolled seizures (fits) disorder as it may cause worsen the condition. It should be used with caution in patients with liver cirrhosis, eczema, psoriasis, or crusted scabies.

• HALOPERIDOL
• THEOPHYLLINE
• IMIPENEM
• PENICILLIN
• BUPROPION
• CYCLOSPORINE
• TACROLIMUS
• MYCOPHENOLATE MOFETIL
• PYRIMETHAMINE
• CHLOROQUINE
• ISONIAZID
• MEPERIDINE
• METHOCARBAMOL
• IOPAMIDOL
• IOHEXOL
• CIPROFLOXACIN
• OFLOXACIN
• NORFLOXACIN

• Limit dairy intake such as milk, curd, and cheese as they may trigger skin irritation.
• Avoid hot showers or hot water to bathe to prevent worsening of the condition.
• Wash the clothes and bedsheets with soap and hot water or dry clean them after every use.
• Avoid sharing personal belongings such as combs, towels, razors, clothes, or bedding with others as it may increase the risk of transmission.
• Do not have close physical contact or sex until the treatment is completed.

• Avoid contact of Scabizine 1% Lotion with eyes. In case of accidental contact, rinse with water thoroughly.
• Do not apply Scabizine 1% Lotion on lots of broken skin, crusted (scabby), or open sores on the skin.
• Wear gloves that are least permeable to Scabizine 1% Lotion such as sheer vinyl, nitrile, or latex with neoprene to avoid Scabizine 1% Lotion getting on hands while applying to someone else. Avoid natural latex gloves as they are more permeable to Scabizine 1% Lotion and thoroughly wash your hands after application.
• Do not cover the treated area with unbreathable things like tight or plastic clothes, plastic lining, blankets, or diapers.
• Avoid contact with other people’s skin after applying Scabizine 1% Lotion, and especially you should not touch a baby or small child.
• Avoid scratching the skin as it may worsen the infection.
• Avoid direct skin-to-skin contact. Seek medical help if your sexual partner also develops scabies.
• Avoid using any oil on hair or skin just before or after applying Scabizine 1% Lotion as oils may increase the absorption of Scabizine 1% Lotion and cause adverse effects. Oils include moisturizers, skin lotions, oil-based conditioners, and hair products.

Scabies: It is a skin condition caused by mites known as Sarcoptes scabiei. It causes an itchy skin rash and is contagious (spreads from one person to another person). These tiny mites crawl under the skin and live on the skin for months laying eggs, and causing severe itching. Scabies spreads easily throughout the body except for the head. Hence, it should be treated quickly. The most commonly seen symptom is an intensely itchy rash that worsens at night. People who live in nursing homes, university halls of residence, or nurseries are at more risk of spreading scabies from person to person due to close contact.

Pediculosis: It is the infection caused by the parasite, Pediculus humanus. It is an ectoparasite and feeds on blood. It infects the hairy parts of the body, such as the scalp and pubic area. In this condition, lice attach to the scalp and lay eggs at the base of the hair. It can be easily transmitted from one person to another through direct contact. The symptom includes intense itching or scratching at the affected area.