Samlifen 10mg Tablet belongs to the group of medications called ‘urinary antagonists' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably, thereby causing an urgent need to urinate, frequent urination, and inability to control urination. Besides this, Samlifen 10mg Tablet is also used for the treatment of neurogenic detrusor overactivity (a bladder control condition caused by neurological problems) in children 2 years and above.

Samlifen 10mg Tablet contains ‘Solifenacin’ that relaxes the urinary bladder muscles, which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Samlifen 10mg Tablet stops these sudden contractions of urinary bladder muscles, thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder.

Take Samlifen 10mg Tablet as prescribed by the doctor. Common side effects of Samlifen 10mg Tablet are dry mouth, blurred vision, constipation, nausea, dyspepsia (indigestion), abdominal pain, burping or belching, heartburn, and stomach upset. Inform your doctor if these side effects do not go away or get worse.

Do not take Samlifen 10mg Tablet if you are allergic to ‘solifenacin’ or any other ingredients present in it. Before taking Samlifen 10mg Tablet, inform your doctor if you have kidney disease, liver disease, bladder blockage, myasthenia gravis (a muscle disease), stomach or bowel problems (including constipation), glaucoma (increased pressure in the eye causing loss of vision), or a history of heart rhythm problems (including QT prolongation). Also, inform your doctor if you are pregnant or breastfeeding. Inform your doctor if you have an intolerance to sugars, as this medicine contains lactose. Do not take grapefruit or grapefruit juice with this medication. Avoid driving or operating heavy machinery, as this medicine may cause dizziness.

Samlifen 10mg Tablet contains ‘solifenacin’, which belongs to the class of medications called 'anticholinergics'. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder, causing the patient to have frequent urges to urinate. Samlifen 10mg Tablet can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine that can be held by your bladder.

• Dry mouth

• Blurred vision

• Constipation

• Nausea

• Dyspepsia (indigestion)

• Urinary tract infections

• Blurred vision

• Abdominal pain

• Burping or belching

• Heartburn

• Stomach upset

Do not take Samlifen 10mg Tablet if you are allergic to ‘solifenacin’ or any contents of it. Before taking Samlifen 10mg Tablet, inform your doctor if you are pregnant or breastfeeding or if you have kidney disease, liver disease, bladder blockage, controlled narrow-angle glaucoma, or stomach or bowel problems (including constipation), or a history of heart rhythm problems (including QT prolongation). Samlifen 10mg Tablet has lactose, so inform your doctor if you have an intolerance to any sugars. Samlifen 10mg Tablet may cause dizziness or blurred vision. So, do not drive or operate any heavy machinery. It can increase body temperature by decreasing sweating. So, avoid hot weather or doing strenuous exercise as this may cause overheating leading to unwanted effects. 

Drug-Drug interactions: Samlifen 10mg Tablet may interact with other anticholinergic medicines, cholinergic drugs,  gastrointestinal agents (metoclopramide and cisapride), antifungal drugs (ketoconazole and itraconazole), drugs used to treat HIV (ritonavir and nelfinavir), antihypertensives (verapamil and diltiazem), antibiotic (rifampicin), antiepileptic drugs (phenytoin and carbamazepine), and bisphosphonates.

Drug-Food interactions: Do not take grapefruit or grapefruit juice while using Samlifen 10mg Tablet.

Drug-Disease interactions: Samlifen 10mg Tablet should be used with caution in patients with urinary retention (inability to urinate), severe stomach or bowel conditions, myasthenia gravis (a muscle disease), glaucoma (eye problem), kidney dialysis, severe liver disease, and severe kidney disease.

• METOCLOPRAMIDE
• CISAPRIDE
• KETOCONAZOLE
• RITONAVIR
• NELFINAVIR
• ITRACONAZOLE
• VERAPAMIL
• DILTIAZEM
• RIFAMPICIN
• PHENYTOIN
• CARBAMAZEPINE

• Eat fresh fruits like pears, banana, citrus fruits, and green vegetables like beans and potatoes. 

• Try to take cranberry juice as it helps in minimizing urinary infections. 

• Avoid coffee, tea, and carbonated drinks which contains caffeine. 

• Do not consume processed, fried, or spicy foods, as these foods can irritate your bladder. 

• Limit alcohol intake as it can increase the risk of side-effects.

• Quit smoking and exercise regularly. 

• Samlifen 10mg Tablet is not recommended for the children less than 2 years of age.

• Intake of Samlifen 10mg Tablet can make you sweat less, thereby increasing the chance of having a heat stroke in summer. So avoid doing tasks which may cause to overheat. 

• Intake of Samlifen 10mg Tablet may occasionally cause blurry vision and dizziness so avoid driving a motor vehicle, operate heavy machinery and performing hazardous tasks which require mental alertness as well. 

Overactive bladder (OAB): In normal conditions, when the urinary bladder is filled with urine, it sends a message to the brain that an individual is ready to urinate. During the urination process, bladder muscles contract, which ultimately leads to a uniform flow of urine. Contrary to this, in an Overactive bladder (OAB), the urinary bladder muscles start contracting before the urine is filled in the urinary bladder, thereby causing frequent urges to urinate. Samlifen 10mg Tablet prevents these sudden bladder muscle contractions and increases the volume and amount of urine that the bladder can hold. Thus, Samlifen 10mg Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong urge to urinate, frequent urination and reduced urine flow.