Salazopyrin 500mg Tablet

Salazopyrin 500mg Tablet is used to treat bowel diseases (ulcerative colitis, Crohn's disease), skin-related problems (psoriasis), and chronic joint diseases (rheumatoid arthritis, ankylosing spondylitis) in children and adults. 

Salazopyrin 500mg Tablet works as an inflammation reducer by acting locally, inhibiting the formation of a chemical known as prostaglandins, which control pain and inflammation. Together, it helps reduce the inflammation of the intestine, skin, and joints. 

Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience a sore throat, a fever, unexplained bruising, or ringing in your ears (tinnitus). Most of these side effects of Salazopyrin 500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Salazopyrin 500mg Tablet can also lower your sperm count, leading to a temporary decrease in male fertility. In this case, you can speak to your doctor. Your doctor might arrange a blood test before you start taking Salazopyrin 500mg Tablet. You can continue taking Salazopyrin 500mg Tablet to prevent flares up during the pregnancy. Besides this, your doctor may prescribe additional folic acid supplements during pregnancy because Salazopyrin 500mg Tablet may reduce the level of folic acid in your body. Salazopyrin 500mg Tablet can be safely taken while you are breastfeeding unless the baby is premature or at risk of jaundice.

Salazopyrin 500mg Tablet works by reducing the inflammation in the colon. It inhibits the formation of a chemical, prostaglandin, which controls inflammation. Together, they help in reducing the inflammation at all the sites like joints, skin, and bowel (intestines), thereby treating a wider range of joint, skin and bowel diseases, including ulcerative colitis, Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis. Salazopyrin 500mg Tablet is not a pain killer. Rather, it is an anti-inflammatory.

• Headache
• Indigestion
• Nausea
• Watery diarrhoea

 Salazopyrin 500mg Tablet treatment is generally considered to be safe during pregnancy, but its usage in pregnant mothers should be discussed with the doctor if planning for pregnancy. This medication should be avoided in breastfeeding mothers as it passes into the milk and causes jaundice and brain problems in infants less than 2 years of age. Tell your doctor if you have an allergy to any other sulpha drugs (sulfonamide antibiotic) as it may cause serious skin allergies like urticaria and stevens johnson’s syndrome. In men, an intake of Salazopyrin 500mg Tablet may lower the sperm count, which improves after stopping this medicine. Tell your doctor if you have asthma, wheezing, fever, breathing difficulties, sudden severe skin rash, unusual bleeding, sore throat, fever, unexplained bruising, or any other symptoms of infection. Use of Salazopyrin 500mg Tablet may change the colour of your urine, contact lenses, and tears to yellow/orange and even make your skin more sensitive to the sunlight. But, this is normal, harmless, and nothing to worry about. You may low folic acid in pregnancy while taking Salazopyrin 500mg Tablet so your doctor might prescribe you iron or folic acid supplements.

Drug-Drug Interaction: Salazopyrin 500mg Tablet may interact with blood thinner (warfarin), heart disease medicine (digoxin), iron supplements (folate), anti-diabetic medicine (glimepiride, glyburide, glipizide, antibiotics (methenamine), immune system affecting drug (azathioprine, mercaptopurine), anti-arthritis or anti-cancer drug (methotrexate) and anti TB drug (isoniazid). 

Drug-Food Interaction: No relevant interaction be found. 

Drug-Disease Interaction: Salazopyrin 500mg Tablet should not be given to the people affected with colitis intestinal obstruction, urinary obstruction, hematologic toxicity, hypersensitivity or allergic reactions, liver disease, porphyria and kidney disease.

• WARFARIN
• DIGOXIN
• GLIMEPIRIDE
• GLYBURIDE
• GLIPIZIDE
• METHENAMINE
• AZATHIOPRINE
• MERCAPTOPURINE
• METHOTREXATE
• ISONIAZID

•  It is advised to drink plenty of water to prevent the occurrence of kidney stones.

•  Take low fibre foods such as white rice, white pasta, bread, egg, fish, tofu, butter, etc. to avoid triggering ulcerative colitis.

•  Exercise regularly to suppress inflammation in the body.

•  Manage stress by doing meditation and deep breathing exercises.

•  Eat smaller meals to avoid pain in the stomach.

•  Avoid foods that can increase or worsen ulcerative colitis such as milk, milk products, raw fruits and vegetables, beans, spicy foods, popcorn, artificial sweeteners, nuts, seeds, and fatty foods.

 It is advised to drink plenty of water to prevent the occurrence of kidney stones or crystalloids.

Ulcerative colitis: It is an inflammatory disease of the bowels that causes irritation, inflammation, and ulcers in the lining of the large intestine (colon).

Crohn’s disease: It is an inflammatory bowel disease (IBD) characterized by inflammation of the digestive tract.

Psoriasis: It is a skin disease in which our skin cells start multiplying faster, building up bumpy red patches covered with white scales.

Rheumatoid arthritis and Ankylosing spondylitis: They are the most common rheumatic diseases affecting joints and the spine, leading to chronic inflammation and painful conditions, ultimately leading to disability.