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  3. SAFEGUAR DSR TABLET

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
SAFEGUAR DSR TABLET is used to reduce pain and swelling associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It contains diclofenac and misoprostol which works by inhibiting the release of chemical messengers that cause pain and protecting the stomach lining from acid. In some cases, this medicine may cause side effects such as diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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SAFEGUAR DSR TABLET, Pack of 15 TABLETS
SAFEGUAR DSR TABLET, Pack of 15 TABLETS
SAFEGUAR DSR TABLET, Pack of 15 TABLETS
SAFEGUAR DSR TABLET, Pack of 15 TABLETS
SAFEGUAR DSR TABLET, Pack of 15 TABLETS
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Composition :

DICLOFENAC-100MG + MISOPROSTOL-200MCG

Manufacturer/Marketer :

Pulse Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About SAFEGUAR DSR TABLET

SAFEGUAR DSR TABLET belongs to a class of non-steroidal anti-inflammatory drugs used to reduce pain and swelling in the joints associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The arthritis symptoms include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

SAFEGUAR DSR TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Take SAFEGUAR DSR TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take SAFEGUAR DSR TABLET for as long as your doctor has prescribed it for you. You may experience diarrhoea, stomach/abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of SAFEGUAR DSR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before using the SAFEGUAR DSR TABLET, tell your doctor if you have had a heart attack or stroke, stomach or bowel disorder, liver disease, porphyria ( inherited blood disorder), asthma, high blood pressure, diabetes, and stomach or intestinal bleeding. Do not take SAFEGUAR DSR TABLET if you are a pregnant or breastfeeding woman. Consumption of alcohol should be avoided during the treatment with SAFEGUAR DSR TABLET as it may lead to an increased risk of liver damage. SAFEGUAR DSR TABLET is not recommended for use in children. Limit alcoholic beverages while on this medication.

Uses of SAFEGUAR DSR TABLET

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

SAFEGUAR DSR TABLET is used to treat aches and pains and musculoskeletal and joint pain problems due to arthritis. SAFEGUAR DSR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

How SAFEGUAR DSR TABLET Works

SAFEGUAR DSR TABLET is a combination drug containing diclofenac and misoprostol. Diclofenac works by blocking the chemical effect of an enzyme called cyclo-oxygenase (COX), which produces prostaglandins (mediators of pain and inflammation) that are responsible for the sense of pain and inflammation (redness and swelling). Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. It works by protecting the stomach lining by reducing the amount of acid in contact with it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SAFEGUAR DSR TABLET

  • Diarrhea
  • Stomach/abdominal pain
  • Nausea
  • Heartburn
  • Difficulty sleeping
  • Ulcers in the stomach or intestines
  • Drowsiness
  • Dizziness
  • Indigestion

What if I have taken an overdose of SAFEGUAR DSR TABLET

Take SAFEGUAR DSR TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include stomach pain, nausea, vomiting, diarrhoea, confusion, drowsiness, low muscle tone, uncontrollable shaking of a part of the body, seizures, shortness of breath, fever, and fast, pounding, or slow heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with SAFEGUAR DSR TABLET. Patients with stomach ulcers, gastric bleeding, heart failure, and high blood pressure should not take SAFEGUAR DSR TABLET. If pregnant or breastfeeding, do not take SAFEGUAR DSR TABLET without talking with the doctor. SAFEGUAR DSR TABLET is not recommended for children below 18 years old. Seek medical help immediately if you have signs of a heart attack or stroke. Stop using SAFEGUAR DSR TABLET and call your doctor immediately if you notice heart problems, kidney problems, liver problems, or stomach bleeding signs.

Drug-Drug Interactions

verifiedApollotooltip
DiclofenacMeloxicam
Critical
MisoprostolOxytocin
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with SAFEGUAR DSR TABLET:
Co-administration of SAFEGUAR DSR TABLET with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with SAFEGUAR DSR TABLET is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
MisoprostolOxytocin
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Coadministration of SAFEGUAR DSR TABLET and Oxytocin can enhance the action of oxytocin. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking SAFEGUAR DSR TABLET and Oxytocin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden or severe stomach pain, unexplained vaginal bleeding, Fast heart rate or low blood pressure in the pregnant person, diarrhea, or dehydration, consult to a doctor. Do not discontinue any medications without consulting a doctor.
MisoprostolDinoprostone
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Combined use of SAFEGUAR DSR TABLET and Dinoprostone can affect the metabolism of SAFEGUAR DSR TABLET.

How to manage the interaction:
Taking SAFEGUAR DSR TABLET and Dinoprostone together can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Coadministration of SAFEGUAR DSR TABLET with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between SAFEGUAR DSR TABLET and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacRivaroxaban
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Co-administration of Rivaroxaban together with SAFEGUAR DSR TABLET may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of SAFEGUAR DSR TABLET and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetorolac
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Coadministration of SAFEGUAR DSR TABLET and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of SAFEGUAR DSR TABLET and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Taking SAFEGUAR DSR TABLET and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of SAFEGUAR DSR TABLET and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Taking SAFEGUAR DSR TABLET with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between SAFEGUAR DSR TABLET and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacAcalabrutinib
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Taking acalabrutinib together with SAFEGUAR DSR TABLET may increase the risk of bleeding.

How to manage the interaction:
Co-administration of SAFEGUAR DSR TABLET and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacKetoconazole
Severe
How does the drug interact with SAFEGUAR DSR TABLET:
Coadministration of SAFEGUAR DSR TABLET with Ketoconazole may increase the risk of liver problems.

How to manage the interaction:
There may be a possible interaction between SAFEGUAR DSR TABLET and Ketoconazole, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

Do not consume alcohol along with SAFEGUAR DSR TABLET as it can cause unpleasant side-effects like gastric bleeding.

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Pregnancy

Unsafe

Please consult your doctor if you are pregnant; your doctor will prescribe SAFEGUAR DSR TABLET only if the benefits outweigh the risks. Taking SAFEGUAR DSR TABLET in the last 20 weeks of pregnancy may cause serious kidney or heart problems in the unborn baby.

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Breast Feeding

Caution

While SAFEGUAR DSR TABLET may pass in the lactating mother's breast milk, So, do it is advisable to take it only if prescribed by your doctor.

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Driving

Caution

SAFEGUAR DSR TABLET may cause dizziness and drowsiness. So, if you observe such symptoms, do not drive.

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Liver

Caution

Limited information was available for the use of SAFEGUAR DSR TABLET in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using SAFEGUAR DSR TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Limited information was available for the use of SAFEGUAR DSR TABLET in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using SAFEGUAR DSR TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

SAFEGUAR DSR TABLET not recommended for children under 18 years of age.

FAQs

SAFEGUAR DSR TABLET is used to reduce pain and swelling associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
SAFEGUAR DSR TABLET contains diclofenac and misoprostol. Diclofenac works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling. Misoprostol is a prostaglandin that helps to protect the stomach from diclofenac's irritating effects. Thereby, SAFEGUAR DSR TABLET helps in relieving pain and swelling associated with different types of arthritis.
No, SAFEGUAR DSR TABLET is not a narcotic pain killer. It belongs to the non-steroidal anti-inflammatory drugs (NSAIDs) group of medications.
Yes, SAFEGUAR DSR TABLET can cause dizziness in some patients. They may experience symptoms such as the feeling of fainting, weakness, or lightheadedness.
SAFEGUAR DSR TABLET may increase the risk of heart problems such as heart attack, especially when used in high doses or for a prolonged duration, and in patients who are smokers, have high blood pressure, diabetes, or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking SAFEGUAR DSR TABLET. However, it is recommended to take SAFEGUAR DSR TABLET in the dose and for the duration as prescribed by your doctor.
SAFEGUAR DSR TABLET is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.
No, SAFEGUAR DSR TABLET does not cure arthritis. SAFEGUAR DSR TABLET is only used to relieve symptoms of arthritis such as joint pain, swelling, and stiffness.
SAFEGUAR DSR TABLET is used to treat pain associated with arthritis. If you have a toothache, it is recommended that you consult your doctor before using SAFEGUAR DSR TABLET.
SAFEGUAR DSR TABLET may cause gastrointestinal problems. Therefore, do not take SAFEGUAR DSR TABLET if you have acid reflux or abdominal pain without consulting the doctor.
It's generally not recommended to take SAFEGUAR DSR TABLET with blood pressure medication without consulting your doctor as it may increase blood pressure and reduce the effectiveness of blood pressure medications.
The common side effects of SAFEGUAR DSR TABLET include diarrhoea, stomach or abdominal pain, nausea, heartburn, drowsiness, and dizziness. Most of the side effects of SAFEGUAR DSR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

4F10, Ballad Estates, Tarnaka, Hyderabad - 500017, TS, India.
Other Info - SAF0011

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Author Details

Doctor imageDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Doctor imageDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:47 PM IST

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Reference

  1. https://www.drugs.com/diclofenac.html
  2. https://www.medicines.org.uk/emc/files/pil.2660.pdf
  3. https://www.medicines.org.uk/emc/files/pil.1642.pdf
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