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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:31 AM IST

S-One Trio Capsule contains Tegafur, Gimeracil and Oteracil, a group of anti-cancer medicines used to treat stomach/gastric cancer. Together, these medications work by inhibiting the genetic material and preventing the growth of cancer cells. Thereby, it helps treat stomach cancer. Sometimes, S-One Trio Capsule may cause side effects, such as nausea, vomiting, diarrhoea, and constipation. Discuss with your doctor if any of the side effects persist or worsen.

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Prescription drug

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About S-One Trio Capsule

S-One Trio Capsule is indicated in the treatment of stomach/gastric cancer. Stomach (gastric) cancer is a type of cancer that originates in the cells lining the stomach. Symptoms may include feeling bloated after eating, nausea, heartburn or indigestion.

S-One Trio Capsule contains Tegafur, Gimeracil and Oteracil, which work by inhibiting the genetic material and preventing the growth of cancer cells. Thereby, it helps treat stomach cancer.

In some cases, S-One Trio Capsule may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use S-One Trio Capsule if you are pregnant or breastfeeding. S-One Trio Capsule is not recommended for children as safety and effectiveness have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of S-One Trio Capsule

Treatment of gastric/stomach cancer

Medicinal Benefits

S-One Trio Capsule is indicated in the treatment of stomach/gastric cancer. S-One Trio Capsule contains Tegafur, Gimeracil and Oteracil. Tegafur is converted into the active drug 5FU (fluorouracil) in the liver and then absorbed by tumour cells. It inhibits the synthesis of genetic material (DNA and RNA) and prevents the growth of cancer cells. Gimeracil prevents the degradation of 5FU, and Oteracil inhibits the gastrointestinal toxicity of 5FU. Together, S-One Trio Capsule helps treat stomach cancer.

Side Effects of S-One Trio Capsule

  • Diarrhoea
  • Nausea
  • Vomiting
  • Constipation

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it. Take the capsule 1 hour before or 1 hour after a meal or as advised by the doctor.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take S-One Trio Capsule if you are allergic to any of its components, if you are pregnant or breastfeeding, if you have a history of severe and unexpected reactions to fluoropyrimidine therapy, known dihydropyrimidine dehydrogenase (DPD) deficiency, severe bone marrow suppression, or end-stage renal disease requiring dialysis. Inform the doctor if you have bone marrow suppression, diarrhoea, dehydration, kidney or liver problems, or eye toxicity. S-One Trio Capsule is not recommended for use in children below 18 years. Let the doctor know if you take other medicines, including supplements and herbal products.

Therapeutic Class

CHEMOTHERAPY

Diet & Lifestyle Advise

  • Light exercises are recommended as they promote mobility, balance, and well-being.
  • Rest well when you are feeling tired.
  • Maintain adequate hydration unless informed by the doctor to restrict fluids.
  • Avoid drinking fluid with meals, particularly carbonated beverages.
  • Do not consume caffeine, spicy and processed foods.
  • Limit alcohol consumption and avoid smoking.
  • Include fruits, vegetables, and whole grains in your diet.
  • Maintain a healthy body weight.
  • Cut down on salty foods.

Habit Forming

No

How S-One Trio Capsule Works

S-One Trio Capsule contains Tegafur, Gimeracil and Oteracil. Tegafur is converted into the active drug 5FU (fluorouracil) in the liver and then absorbed by tumour cells. It inhibits the synthesis of genetic material (DNA and RNA) and prevents the growth of cancer cells. Gimeracil prevents the degradation of 5FU, and Oteracil inhibits the gastrointestinal toxicity of 5FU. Together, S-One Trio Capsule helps treat stomach cancer.

What if I have taken an overdose of S-One Trio Capsule

Do not take more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you think there has been an overdose, or experience any adverse events get medical care right away.
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Alcohol

Consult your doctor

It is not known if alcohol affects S-One Trio Capsule. Please consult your doctor. 

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Pregnancy

Unsafe

S-One Trio Capsule is not recommended during pregnancy as it may cause foetal harm. Consult the doctor immediately if you become pregnant during treatment with S-One Trio Capsule.

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Breast Feeding

Unsafe

It is not known if this medicine passes into breast milk. Therefore, breastfeeding is not recommended during treatment with S-One Trio Capsule.

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Driving

Caution

S-One Trio Capsule may cause fatigue, dizziness and blurred vision. Drive or operate heavy machinery only if you are alert.

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Liver

Consult your doctor

Consult the doctor if you have a history of liver problems.

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Kidney

Caution

S-One Trio Capsule is not recommended in patients with end-stage renal disease requiring dialysis. Consult the doctor if you have kidney problems.

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Children

Unsafe

S-One Trio Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India
Other Info - SO28515

Author Details

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FAQs

S-One Trio Capsule is used to treat gastric/stomach cancer.
S-One Trio Capsule works by preventing the growth of cancer cells. Thereby, it helps treat stomach cancer.
S-One Trio Capsule may have anti-fertility effects, which may be irreversible. Talk to the doctor regarding fertility preservation prior to the start of the treatment or if you have any concerns.
Diarrhoea could be a side effect of S-One Trio Capsule. Consult the doctor if you experience diarrhoea. The doctor may monitor you carefully and give fluid/electrolyte replacement if you are dehydrated.

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