S-One Trio-20 Capsule is indicated in the treatment of stomach/gastric cancer. Stomach (gastric) cancer is a type of cancer that originates in the cells lining the stomach. Symptoms may include feeling bloated after eating, nausea, heartburn or indigestion.

S-One Trio-20 Capsule contains Tegafur, Gimeracil and Oteracil, which work by inhibiting the genetic material and preventing the growth of cancer cells. Thereby, it helps treat stomach cancer.

In some cases, S-One Trio-20 Capsule may cause side effects such as nausea, vomiting, diarrhoea, and constipation. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use S-One Trio-20 Capsule if you are pregnant or breastfeeding. S-One Trio-20 Capsule is not recommended for children as safety and effectiveness have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

S-One Trio-20 Capsule is indicated in the treatment of stomach/gastric cancer. S-One Trio-20 Capsule contains Tegafur, Gimeracil and Oteracil. Tegafur is converted into the active drug 5FU (fluorouracil) in the liver and then absorbed by tumour cells. It inhibits the synthesis of genetic material (DNA and RNA) and prevents the growth of cancer cells. Gimeracil prevents the degradation of 5FU, and Oteracil inhibits the gastrointestinal toxicity of 5FU. Together, S-One Trio-20 Capsule helps treat stomach cancer.

• Diarrhoea
• Nausea
• Vomiting
• Constipation

Do not take S-One Trio-20 Capsule if you are allergic to any of its components, if you are pregnant or breastfeeding, if you have a history of severe and unexpected reactions to fluoropyrimidine therapy, known dihydropyrimidine dehydrogenase (DPD) deficiency, severe bone marrow suppression, or end-stage renal disease requiring dialysis. Inform the doctor if you have bone marrow suppression, diarrhoea, dehydration, kidney or liver problems, or eye toxicity. S-One Trio-20 Capsule is not recommended for use in children below 18 years. Let the doctor know if you take other medicines, including supplements and herbal products.

Drug-Drug Interactions: Inform the doctor if you are taking fluoropyrimidines (capecitabine, 5-FU, flucytosine), CYP2A6 inhibitors, or anti-viral agents (sorivudine, brivudine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have bone marrow suppression, end-stage kidney disease, glucose/galactose intolerance, or malabsorption.

• CAPECITABINE
• 5 FLUOROURACIL
• FLUCYTOSINE
• SORIVUDINE
• BRIVUDINE

• Light exercises are recommended as they promote mobility, balance, and well-being.
• Rest well when you are feeling tired.
• Maintain adequate hydration unless informed by the doctor to restrict fluids.
• Avoid drinking fluid with meals, particularly carbonated beverages.
• Do not consume caffeine, spicy and processed foods.
• Limit alcohol consumption and avoid smoking.
• Include fruits, vegetables, and whole grains in your diet.
• Maintain a healthy body weight.
• Cut down on salty foods.

• Women of childbearing potential are advised to avoid becoming pregnant during treatment with S-One Trio-20 Capsule. Consult the doctor immediately if you become pregnant during treatment.
• Both male and female patients should take contraceptive measures during treatment and for 6 months after stopping the treatment.

Stomach/gastric cancer: Stomach (gastric) cancer is a type of cancer that originates in the cells lining the stomach. During the early stages of the disease, there may be no noticeable symptoms. However, as the cancer progresses, the symptoms include feeling bloated after eating, feeling full after consuming small quantities of food, nausea, heartburn or indigestion. Risk factors that may increase the likelihood of developing stomach cancer include smoking and a diet that consists of highly processed or salty foods. Treatment options for stomach cancer include surgery, medication, radiation and chemotherapy.