apollo
0
Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Ryzodeg 100IU/ml Penfill 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children. It contains Insulin Aspart and Insulin Degludec, which help lower blood sugar levels after food intake. It confirms rapid and stable sugar control by helping reuptake of sugar in fat cells and muscle and suppressing sugar production in the liver. It may cause side effects such as rash, injection site allergic reaction, weight gain, oedema (tissue swelling or fluid overload), lipodystrophy (skin thickening or pits at the injection site), hypoglycemia (low blood glucose level), and itching. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions. Along with this medicine, you should take a healthy diet, do regular exercise, and maintain healthy weight for effective results.
Read more
770 people bought
in last 7 days
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Abbott India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Ryzodeg 100IU/ml Penfill 3 ml

Ryzodeg 100IU/ml Penfill 3 ml used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children. In Diabetes Mellitus Type 1, the body does not produce enough insulin to regulate blood sugar levels. On the other hand, in Diabetes Mellitus type 2, either the body stops producing enough insulin (a hormone that helps lower blood sugar levels), or there is resistance to insulin action. As a result, insulin is produced in large quantities, but it is not capable of operating on the body's organs.

Ryzodeg 100IU/ml Penfill 3 ml is a combination of two drugs, namely, Insulin Aspart and Insulin Degludec. Insulin aspart is a fast-acting or short-acting form of insulin that helps lower blood sugar levels after food intake. Insulin degludec is a long-acting form of insulin which begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). Ryzodeg 100IU/ml Penfill 3 ml stimulates the recovery of sugar in muscle and fat cells and suppresses sugar production in the liver. Together, Ryzodeg 100IU/ml Penfill 3 ml confirms rapid and stable sugar control by helping reuptake of sugar in fat cells and muscle and suppressing the creation of sugar in the liver.

Take Ryzodeg 100IU/ml Penfill 3 ml as prescribed by your doctor. You are advised to take Ryzodeg 100IU/ml Penfill 3 ml as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience rash, injection site allergic reaction, weight gain, oedema (tissue swelling or fluid overload), lipodystrophy (skin thickening or pits at the injection site), hypoglycemia (low blood glucose level), and itching. Most of these side effects of Ryzodeg 100IU/ml Penfill 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Ryzodeg 100IU/ml Penfill 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Ryzodeg 100IU/ml Penfill 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Ryzodeg 100IU/ml Penfill 3 ml, you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor. Ryzodeg 100IU/ml Penfill 3 ml is a cold chain medicine, and so it must be stored in the refrigerator between 2-8 degrees Celsius, or else its efficiency might get lost. Do not store in the freezer or the fridge.

Uses of Ryzodeg 100IU/ml Penfill 3 ml

Treatment of Type 1 diabetes mellitus, Type 2 diabetes mellitus

Medicinal Benefits

Ryzodeg 100IU/ml Penfill 3 ml belongs to the class of medications called ‘antidiabetics’ primarily used for the treatment of both type 1 and type 2 diabetes mellitus. Ryzodeg 100IU/ml Penfill 3 ml is a combination of two drugs, namely, Insulin Aspart and Insulin Degludec. Ryzodeg 100IU/ml Penfill 3 ml contains insulin aspart, which is a fast-acting form of insulin that helps lower blood sugar levels after food intake. Ryzodeg 100IU/ml Penfill 3 ml contains insulin degludec, which is a prolonged action form of insulin. It typically begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). Together, they confirm rapid and stable sugar control by helping reuptake sugar in fat and muscle, and cells and suppressing the creation of sugar in the liver. 

Directions for Use

Ryzodeg 100IU/ml Penfill 3 ml should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). If you are not trained to self-administer Ryzodeg 100IU/ml Penfill 3 ml, ask your healthcare professional to administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ryzodeg 100IU/ml Penfill 3 ml

  • Rashes
  • Injection site allergic reaction
  • Weight gain
  • Edema (swelling)
  • Lipodystrophy (skin thickening or pits at the injection site)
  • Hypoglycemia (low blood glucose level)
  • Itching

Drug Warnings

Ryzodeg 100IU/ml Penfill 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. If you are changing the insulin brand or injecting your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first hyperglycemia symptoms (high blood sugar level) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Ryzodeg 100IU/ml Penfill 3 ml may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death. Do not take Ryzodeg 100IU/ml Penfill 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interaction: Ryzodeg 100IU/ml Penfill 3 ml may have an interaction with pain killers (aspirin), antibiotics (isoniazid, pentamidine, ciprofloxacin), blood sugar enhancing pills (glucagon), male hormone testosterone analogue (danazol), antidiabetics (metformin), lipid-lowering pills (reserpine, niacin), blood pressure-lowering medicines (atenolol, acebutolol, metoprolol), thyroid hormones (levothyroxine), an antidepressant (fluoxetine, lithium), female sex hormones (progestogen, estrogen).

Drug-Food Interaction: Ryzodeg 100IU/ml Penfill 3 ml may interact with an ayurvedic, homeopathy, Unani, herbal supplements, or OTC items. Tell your doctor if you are using these products. Try to avoid alcoholic beverages with Ryzodeg 100IU/ml Penfill 3 ml as it may increase or decrease your blood sugar level.

Drug-Disease Interaction: Ryzodeg 100IU/ml Penfill 3 ml should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ISONIAZID
  • PENTAMIDINE
  • CIPROFLOXACIN
  • GLUCAGON
  • DANAZOL
  • METFORMIN
  • RESERPINE
  • NIACIN
  • ATENOLOL
  • ACEBUTOLOL
  • METOPROLOL
  • LEVOTHYROXINE
  • FLUOXETINE
  • LITHIUM
  • PROGESTERONE
  • ESTROGEN

Habit Forming

No

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.

  • Exercise may also speed up an insulin dose effect, especially if the exercise involves the injection site area (for example, the leg should not be used for injection just before running). 

  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 

  • Avoid eating sugar food and prefer food cooked food low in calories.

  • When travelling across more than 2 time zones, you should talk to your doctor about your insulin schedule adjustments.

Special Advise

  • Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening hypokalemia condition (low potassium). 

  • Store Ryzodeg 100IU/ml Penfill 3 ml between 2-8 degree celsius temperature only. Do not store Ryzodeg 100IU/ml Penfill 3 ml in the freezer. 

Disease/Condition Glossary

Type 1 diabetes mellitus: In type 1 diabetes mellitus, our body does not make insulin (the hormone which helps to decrease sugar levels in the blood) to control blood sugar levels.

Type 2 diabetes mellitus: In type 2 diabetes mellitus, either the body stops producing enough insulin or there is resistance to the action of insulin. As a result, insulin is produced in sufficient amounts but is unable to act on the tissues of the organs.

bannner image

Alcohol

Unsafe

You are recommended not to consume alcohol along with Ryzodeg 100IU/ml Penfill 3 ml to avoid unpleasant side-effects. Alcohol may either decrease or increase the blood sugar level which can be fatal.

bannner image

Pregnancy

Safe if prescribed

Ryzodeg 100IU/ml Penfill 3 ml can be used during pregnancy. Your insulin dose may need to be changed during pregnancy and after delivery.

bannner image

Breast Feeding

Safe if prescribed

Ryzodeg 100IU/ml Penfill 3 ml can be given safely to nursing mothers but only under the supervision of a doctor.

bannner image

Driving

Unsafe

Drive with caution, Ryzodeg 100IU/ml Penfill 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar).

bannner image

Liver

Caution

Ryzodeg 100IU/ml Penfill 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Ryzodeg 100IU/ml Penfill 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Safe if prescribed

Ryzodeg 100IU/ml Penfill 3 ml can be given safely to children; dose has to be prescribed under the supervision of a doctor.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - RYZ0004

FAQs

Ryzodeg 100IU/ml Penfill 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children.
Ryzodeg 100IU/ml Penfill 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Ryzodeg 100IU/ml Penfill 3 ml can be given to you or not depending on your present condition. Ryzodeg 100IU/ml Penfill 3 ml should be avoided in patients who are allergic to Ryzodeg 100IU/ml Penfill 3 ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).
Cold sweat, cool pale skin, headache; rapid heartbeat, feeling sick, feeling very hungry, temporary vision changes, drowsiness, unusual tiredness and weakness, nervousness or tremor, feeling anxious, feeling confused, difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.
If you experience low blood sugar, eat glucose tablets or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness. Consult a doctor immediately.
It is advised to tell all the medicines that you are using to your doctor like pioglitazone or rosiglitazone as taking other diabetes medicines may increase the risk of serious heart problems.
Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
icon image

Keep Refrigerated. Do not freeze.

Add to Cart