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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:52 AM IST

Rynazma 400 mg Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). It contains Doxofylline, which relaxes the bronchial smooth muscle of the lung's airways, making it easier for asthma and COPD patients to breathe easily. It may cause side effects such as headaches, nausea, vomiting, stomach pain, irritability, insomnia (difficulty in falling or staying asleep) or a fast heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Rynazma 400 mg Tablet

Rynazma 400 mg Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Rynazma 400 mg Tablet contains Doxofylline, which acts by inhibiting phosphodiesterase 4 (PD-4), thereby relaxing the bronchial smooth muscle of the lung's airways, making it easier for asthma and COPD patients to breathe easily.

Use Rynazma 400 mg Tablet as prescribed. Your doctor will recommend you how often you take Rynazma 400 mg Tablet based on your medical condition. Some people may experience headaches, nausea, vomiting, stomach pain, irritability, insomnia (difficulty in falling or staying asleep) or a fast heart rate. Most of these side effects of Rynazma 400 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Rynazma 400 mg Tablet is contraindicated in acute myocardial infarction, low blood pressure (hypotension), lactating women and patients allergic to Rynazma 400 mg Tablet . Let your doctor know if you are pregnant or planning for pregnancy, before using Rynazma 400 mg Tablet . Rynazma 400 mg Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance, leading to high blood levels even after stopping treatment with Rynazma 400 mg Tablet .

Uses of Rynazma 400 mg Tablet

Treatment of Asthma, Chronic obstructive pulmonary disease (COPD)

Medicinal Benefits

Rynazma 400 mg Tablet is a bronchodilator and also possesses antitussive (cough suppressant) properties that are used to treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Rynazma 400 mg Tablet works by relaxing muscles and widening the airways of the lungs, especially in asthma and COPD patients. Additionally, Rynazma 400 mg Tablet helps in suppressing cough and makes breathing easier by opening airways. Thus, it prevents an asthma attack, and an individual can exercise freely if it is taken before exercise or before expected exposure to irritants such as pollen, house dust, cigarette smoke and pets.

Directions for Use

Tablet/Capsule: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Syrup: Shake the bottle well before use. Check the label for directions and take it in doses as prescribed by your doctor with the help of a measuring cup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rynazma 400 mg Tablet

  • Headache

  • Nausea

  • Vomiting

  • Stomach pain

  • Irritability

  • Insomnia (difficulty in falling or staying asleep)

  • Fast heart rate

Drug Warnings

If you are allergic to Rynazma 400 mg Tablet or any other medicines, please tell your doctor. You are recommended to avoid taking Rynazma 400 mg Tablet with chocolate and caffeinated foods such as cocoa beans or tea leaves as they may increase the risk of severity of side effects. Rynazma 400 mg Tablet is contraindicated in breastfeeding mothers. If you are pregnant or planning for pregnancy, please consult a doctor before using Rynazma 400 mg Tablet . Do not take Rynazma 400 mg Tablet if you have low blood pressure or had a heart attack. Rynazma 400 mg Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance leading to high blood levels even after stopping treatment with Rynazma 400 mg Tablet . If you have low blood pressure, congestive heart failure, hypoxemia (low oxygen levels in the blood), hyperthyroidism (overactive thyroid), pulmonary heart diseases, stomach ulcer, kidney, liver or heart diseases, inform your doctor before taking Rynazma 400 mg Tablet .

Drug Interactions

Drug-Drug Interaction: Rynazma 400 mg Tablet may interact with medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (erythromycin, clindamycin, lincomycin), drugs used to lower high blood pressure (propranolol), central nervous system stimulant (ephedrine), flu vaccine (influenza vaccine) and anticonvulsants (phenytoin),

Drug-Food Interaction: Rynazma 400 mg Tablet may interact with caffeine. Therefore, avoid intake of Rynazma 400 mg Tablet with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects.

Drug-Disease Interaction: If you have low blood pressure, congestive heart failure, hypoxemia (low oxygen levels in the blood), hyperthyroidism (overactive thyroid), pulmonary heart diseases, stomach ulcer, kidney, liver or heart diseases, inform your doctor before taking Rynazma 400 mg Tablet .

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • CIMETIDINE
  • ERYTHROMYCIN
  • CLINDAMYCIN
  • LINCOMYCIN
  • PROPRANOLOL
  • EPHEDRINE
  • INFLUENZA (LIVE ATTENUATED)
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.

  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.

  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen asthma symptoms.

  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.

  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

  • Quit smoking as it may reduce the effectiveness of the Rynazma 400 mg Tablet and irritate the lungs worsening breathing problem.

Special Advise

  • Regular blood tests are recommended while taking Rynazma 400 mg Tablet to monitor potassium levels and levels of Rynazma 400 mg Tablet in the blood.

  • Rynazma 400 mg Tablet can cause serious side effects, possibly similar, which occurs by taking too much amount of caffeine. So avoid intake of Rynazma 400 mg Tablet with caffeinated beverages like chocolate, coffee etc.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Caution

The interaction of Rynazma 400 mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol with Rynazma 400 mg Tablet .

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Pregnancy

Caution

The safety of Rynazma 400 mg Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Rynazma 400 mg Tablet is contraindicated in breastfeeding mothers. Please consult a doctor before taking Rynazma 400 mg Tablet if you are breastfeeding.

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Driving

Safe if prescribed

Rynazma 400 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Rynazma 400 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Rynazma 400 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Rynazma 400 mg Tablet is not recommended for children below 6 years of age, as the safety and effectiveness were not established. However, please consult a doctor before giving Rynazma 400 mg Tablet for children.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063.
Other Info - RYN0003

Author Details

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FAQs

Rynazma 400 mg Tablet is used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD).
Rynazma 400 mg Tablet contains Doxofylline which belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Additionally, Rynazma 400 mg Tablet possess antitussive (cough suppressant) properties and helps in suppressing cough. Thereby, makes breathing easier by opening airways.
No, you are not recommended to take erythromycin with Rynazma 400 mg Tablet as co-administration of these medicines may increase the risk of adverse effects of Rynazma 400 mg Tablet . However, please consult a doctor before using other medicines with Rynazma 400 mg Tablet .
You are recommended to avoid taking Rynazma 400 mg Tablet if you are allergic to Rynazma 400 mg Tablet or other xanthine derivatives if you are breastfeeding, suffering from low blood pressure or had a heart attack. However, inform your doctor if you have any of these conditions before taking Rynazma 400 mg Tablet .
You are not recommended to take more than the prescribed dose of Rynazma 400 mg Tablet as it may cause overdose resulting in irregular heartbeats and fits. However, if you experience any of these symptoms while taking Rynazma 400 mg Tablet , please consult a doctor immediately.
No, you are not recommended to smoke while taking Rynazma 400 mg Tablet as it may reduce the effectiveness of Rynazma 400 mg Tablet .
No, you are not recommended to stop taking Rynazma 400 mg Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Rynazma 400 mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Rynazma 400 mg Tablet , please consult your doctor.
No, Rynazma 400 mg Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.
Even if you feel well, do not stop using Rynazma 400 mg Tablet as it might cause worsening symptoms. To treat your condition effectually, continue using Rynazma 400 mg Tablet for as long as your doctor has prescribed it.
Rynazma 400 mg Tablet is not recommended for children below 6 years of age, as the safety and effectiveness were not established. However, please consult a doctor before giving Rynazma 400 mg Tablet for children.
Rynazma 400 mg Tablet helps in suppressing cough and makes breathing easier by opening airways. Thus, it prevents an asthma attack.
No, It belongs to the class of bronchodilator (methylxanthine bronchodilator).
No, it belongs to the class of bronchodilators (methylxanthines bronchodilators).

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