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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST

Rupatch 5 mcg Transdermal Patch is primarily used to treat pain. It contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain that is responsible for causing pain. This provides pain relief by acting on specific receptors in the brain. Common side effects of Rupatch 5 mcg Transdermal Patch are drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness, or tiredness.

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Prescription drug

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Synonym

BUPRENORPHINE HCL, BUPRENORPHINE HYDROCHLORIDE

Manufacturer/Marketer

Rusan Pharma Ltd

Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Rupatch 5 mcg Transdermal Patch

Rupatch 5 mcg Transdermal Patch belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Rupatch 5 mcg Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain.

Use Rupatch 5 mcg Transdermal Patch as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Rupatch 5 mcg Transdermal Patch should be avoided if you are allergic to it or any of its ingredients or opioids. Do not use Rupatch 5 mcg Transdermal Patch if you are pregnant or breastfeeding. Rupatch 5 mcg Transdermal Patch is not recommended for children below 18 years of age. Rupatch 5 mcg Transdermal Patch is a habit-forming drug; hence, there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Rupatch 5 mcg Transdermal Patch may decrease fertility in men and women. Do not consume alcohol while using Rupatch 5 mcg Transdermal Patch as it may increase the risk of side effects.

Uses of Rupatch 5 mcg Transdermal Patch

Treatment of Pain

Medicinal Benefits

The Rupatch 5 mcg Transdermal Patch contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Rupatch 5 mcg Transdermal Patch has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses.

Directions for Use

Transdermal Patch: Use Rupatch 5 mcg Transdermal Patch only as prescribed by a doctor. Do not use this medicine for a prolonged period.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rupatch 5 mcg Transdermal Patch

  • Weakness
  • Anxiety
  • Nervousness
  • Dizziness
  • Headache
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Sweating
  • Application site reactions

Drug Warnings

Please do not stop using Rupatch 5 mcg Transdermal Patch suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Rupatch 5 mcg Transdermal Patch or any other medicines, please tell your doctor. Do not use Rupatch 5 mcg Transdermal Patch if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Rupatch 5 mcg Transdermal Patch is not recommended for children below 18 years of age. Avoid consuming alcohol with Rupatch 5 mcg Transdermal Patch as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Rupatch 5 mcg Transdermal Patch should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants.

Drug Interactions

Drug-Drug Interactions: Rupatch 5 mcg Transdermal Patch may have interaction with benzodiazepines (diazepam, temazepam ), pain killers (pentazocine, nalbuphine, codeine, dihydrocodeine, methadone, morphine), anti-depressants (moclobemide, tranylcypromine, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine, amitriptyline, doxepin, trimipramine), antihistamine (promethazine, chlorphenamine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).

Drug-Food Interactions: Rupatch 5 mcg Transdermal Patch may interact with grapefruit juice. Therefore, avoid grapefruit juice intake with Rupatch 5 mcg Transdermal Patch, as it may increase Rupatch 5 mcg Transdermal Patch levels in the body. Also, avoid St. John's wort (an antidepressant plant) and alcohol consumption while using Rupatch 5 mcg Transdermal Patch, as they may increase the risk of adverse effects such as drowsiness, dizziness, and difficulty concentrating.

Drug-Disease Interactions: People with asthma or any other breathing problems, kidney problems, liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression should consult a doctor before using Rupatch 5 mcg Transdermal Patch.

Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • METHADONE
  • FLUOXETINE
  • DIAZEPAM
  • CODEINE
  • MORPHINE
  • AMITRIPTYLINE
  • PROMETHAZINE
  • VENLAFAXINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also strengthen your muscles by lifting light weights.
  • Drink plenty of water during treatment with Rupatch 5 mcg Transdermal Patch to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Rupatch 5 mcg Transdermal Patch.
  • Avoid consumption of alcohol and quit smoking.

Special Advise

  • Do not use Rupatch 5 mcg Transdermal Patch for a prolonged time, as it may lead to mental or physical dependence on Rupatch 5 mcg Transdermal Patch.
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Rupatch 5 mcg Transdermal Patch causes drowsiness. Avoid activities that require your complete focus and attention, like driving, when you are taking this drug.
  • An abrupt stoppage of Rupatch 5 mcg Transdermal Patch can lead to significant withdrawal symptoms. Always discuss decreasing the dosage with your doctor before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Disease/Condition Glossary

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused by pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.

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Alcohol

Unsafe

Consuming alcohol or other illicit drugs during treatment with Rupatch 5 mcg Transdermal Patch increases your chances of experiencing these significant, life-threatening adverse effects. Throughout your therapy, do not consume alcohol, use alcohol-containing prescription or nonprescription medicines, or use street drugs.

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Pregnancy

Unsafe

If you are pregnant or planning pregnancy, inform your doctor. If you use Rupatch 5 mcg Transdermal Patch often throughout your pregnancy, your baby may suffer from potentially fatal withdrawal symptoms after birth. If your infant exhibits any of the following symptoms, contact your doctor straight away: irritability, hyperactivity, disturbed sleep, high-pitched scream, excessive shaking of a portion of the body, vomiting, diarrhoea, or failure to gain weight.

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Breast Feeding

Unsafe

If you are nursing, you should avoid using Rupatch 5 mcg Transdermal Patch. Buprenorphine passes into breast milk in small amounts and might cause respiratory issues in your infant. Talk with your doctor; they may prescribe a different pain reliever.

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Driving

Unsafe

Rupatch 5 mcg Transdermal Patch may cause dizziness, blurred vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after using Rupatch 5 mcg Transdermal Patch.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before using Rupatch 5 mcg Transdermal Patch.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before using Rupatch 5 mcg Transdermal Patch.

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Children

Unsafe

Rupatch 5 mcg Transdermal Patch is not recommended for children below 18 years of age as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

58-D, Government Industrial Estate, Charkop, Kandivli (W), Mumbai 400 067 (India).
Other Info - RUP0026

FAQs

Rupatch 5 mcg Transdermal Patch is used to treat Pain.
Rupatch 5 mcg Transdermal Patch consists of Buprenorphine is an opioid partial agonist. It provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.
No, you are not recommended to take Rupatch 5 mcg Transdermal Patch with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Rupatch 5 mcg Transdermal Patch may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Rupatch 5 mcg Transdermal Patch with other medicines.
Yes, Rupatch 5 mcg Transdermal Patch may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while using Rupatch 5 mcg Transdermal Patch, do not stop using it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.
Yes, Rupatch 5 mcg Transdermal Patch may cause addiction, especially if taken for a prolonged time. Therefore, Rupatch 5 mcg Transdermal Patch should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Rupatch 5 mcg Transdermal Patch only as advised by a doctor, as overuse or misuse of Rupatch 5 mcg Transdermal Patch can lead to overdose or death.

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