Rumef 250mg Tablet comes into the category of 'Antimalarials' mainly used to treat or prevent malaria. Malaria is a life-threatening disease that is spread by the bite of an infected mosquito (anopheles mosquito). When an infected mosquito bites a healthy person, then it transmits the infections into the bloodstream, which after several days starts affecting the red blood cells & liver cells, breaking them in the process. Usually, an infected person starts noticing the symptoms of malaria within 10 days to 4 weeks after the infection that include shaking chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.

Rumef 250mg Tablet contains ‘mefloquine’, which acts by killing the malarial parasites. It works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

Take Rumef 250mg Tablet as prescribed by your doctor. You are advised to take Rumef 250mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience sleeping problems (bad dreams, sleepiness, unable to sleep), headache, dizziness, vertigo (loss of balance), itching, nausea, vomiting, stomach pain or diarrhoea. Most of these side effects of Rumef 250mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking Rumef 250mg Tablet, please inform your doctor if you have any allergy to Rumef 250mg Tablet or its active part. Rumef 250mg Tablet should not be taken in conditions like liver disease, kidney disease, eye problems and epilepsy/ fits disorder. Rumef 250mg Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Rumef 250mg Tablet. Do not drive or use a machine while taking Rumef 250mg Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Rumef 250mg Tablet. Contact your doctor before taking Rumef 250mg Tablet.

Rumef 250mg Tablet falls into a group of medicines known as antimalarials, which are indicated for treating or preventing malaria. Rumef 250mg Tablet contains mefloquine, which is quinoline medicine, that works by enhancing the levels of heme in the blood. Haeme is a substance toxic to the malarial parasite. In this way, the parasite gets killed by its toxic by-products released during its metabolism of hemoglobin. This kills the parasite and prevents the infection from spreading.

• Sleeping problems (bad dreams, sleepiness, unable to sleep)
• Headache
• Dizziness
• Vertigo (loss of balance)
• Itching
• Nausea
• Vomiting
• Stomach pain
• Diarrhoea

Rumef 250mg Tablet should not be taken in conditions like epilepsy/fits, heart problems, liver/ kidney disease, eye problems, inflammation in the lungs, and low blood sugar level. Before taking Rumef 250mg Tablet inform your doctor if you have suicidal thoughts, severe anxiety, abnormal dreams, insomnia (difficulty in sleeping), depression, feeling restless and confusion. Before taking Rumef 250mg Tablet, please inform your doctor if you have any allergy to Rumef 250mg Tablet or its active part Rumef 250mg Tablet should not be given to children less than 3 months. If you are pregnant or breastfeeding, please inform your doctor before taking Rumef 250mg Tablet. Do not drive or use a machine while taking Rumef 250mg Tablet as it causes dizziness. If you have some tolerance for sugar, you should not take Rumef 250mg Tablet. Contact your doctor before taking Rumef 250mg Tablet.

Drug-Drug Interaction: Rumef 250mg Tablet may interact with other antimalarial medicines (chloroquine, quinidine, quinine), antidepressants (amitriptyline), antipsychotics (phenothiazine), medicines for fits/epilepsy (carbamazepine, phenytoin, phenobarbital, valproate), antifungal (ketoconazole), antibiotics (rifampicin, penicillins, cephalosporins), medicines for HIV infections (efavirenz), painkiller (tramadol), blood thinner (warfarin).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have depression, heart disease, fits/ epilepsy and liver disease, inform your doctor before taking Rumef 250mg Tablet.

• CHLOROQUINE
• QUINIDINE
• QUININE
• AMITRIPTYLINE
• PHENOTHIAZINE
• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL
• VALPROATE
• RIFAMPICIN
• PENICILLIN
• KETOCONAZOLE
• EFAVIRENZ
• TRAMADOL
• WARFARIN

• A person should take nutritious food as when a person has a malarial fever, their body's requirement gets increased, and also taking high carbohydrate diet, Fresh fruits and vegetables help in recovering the body fast.
• During fever, a person may experience appetite loss, thus eating food becomes a challenge. To deal with this, one should drink glucose water, fresh fruit juices, coconut water, to supplying the body's requirements through liquids.
• High malaria fever makes the body weak and reduces appetite to take food that helps to synthesize immune bodies and help the body deal with parasites.
• A person should not take very high-fiber foods like green leafy vegetables, and fruits with thick skin, as the body is already in the healing stage and it also has to digest these complex foods.
• Take proper rest, which helps the body to relax and heal faster.

• Take Rumef 250mg Tablet as prescribed by your doctor, do not stop takin if you feel better.
• Your doctor may advice regular eye check up, during the treatment with Rumef 250mg Tablet as it may cause damage to the retina.

Malaria: It is a life-threatening disease caused by parasites that enter the body through the bite of a mosquito. This is a common disease in countries like Africa, South America and Southeast Asia. This disease usually occurs when an infected mosquito (infected with the parasite 'Plasmodium', parasites are organisms that live in other living organisms for their survival) bites a healthy individual then this parasite gets transferred into the bloodstream and starts growing and destroying the red blood cells of the body. There are four parasites responsible for causing malaria that include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Generally, an infected person starts noticing the symptoms within 10 days to 4 weeks after the mosquito bite, which include shaking chills that can range from moderate to high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma and bloody stools.