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Reviewed By Veda Maddala , M Pharmacy
RTU-Doce 80 mg Injection 4 ml is an anti-cancer medicine used in the treatment of breast, lung, prostate, stomach, head/neck cancers. It works by slowing down cell growth, thus preventing the cancer cells from rapidly dividing and spreading. Common side effects include injection site reactions, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, etc.
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Composition :

DOCETAXEL-20MG

Manufacturer/Marketer :

Adley Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About RTU-Doce 80 mg Injection 4 ml

RTU-Doce 80 mg Injection 4 ml belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

RTU-Doce 80 mg Injection 4 ml contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

RTU-Doce 80 mg Injection 4 ml will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of RTU-Doce 80 mg Injection 4 ml include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting RTU-Doce 80 mg Injection 4 ml, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. RTU-Doce 80 mg Injection 4 ml is not indicated for use in pregnant and breastfeeding women. RTU-Doce 80 mg Injection 4 ml may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with RTU-Doce 80 mg Injection 4 ml. RTU-Doce 80 mg Injection 4 ml is not recommended for children below two years of age.

Uses of RTU-Doce 80 mg Injection 4 ml

Treatment of Cancer

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

RTU-Doce 80 mg Injection 4 ml contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

How RTU-Doce 80 mg Injection 4 ml Works

RTU-Doce 80 mg Injection 4 ml contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RTU-Doce 80 mg Injection 4 ml

  • Pain/swelling at the injection site
  • Headache
  • Fatigue
  • Dizziness
  • Drowsiness
  • Constipation
  • Loss of appetite
  • Indigestion
  • Tearing of the eyes
  • Nausea
  • Vomiting
  • Diarrhoea
  • Insomnia (sleeplessness)
  • Fever (please inform your doctor if you have fever)
  • Muscle aches
  • Breathlessness

What if I have taken an overdose of RTU-Doce 80 mg Injection 4 ml

The overdose of RTU-Doce 80 mg Injection 4 ml is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with RTU-Doce 80 mg Injection 4 ml, please inform your doctor immediately.

Drug Warnings

Inform your doctor if you have any allergic reactions to RTU-Doce 80 mg Injection 4 ml or other medications. Before starting RTU-Doce 80 mg Injection 4 ml, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. RTU-Doce 80 mg Injection 4 ml can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, RTU-Doce 80 mg Injection 4 ml is not indicated in pregnancy and breastfeeding women. If you are using RTU-Doce 80 mg Injection 4 ml, use reliable contraception forms to prevent pregnancy during the course. RTU-Doce 80 mg Injection 4 ml can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with RTU-Doce 80 mg Injection 4 ml. RTU-Doce 80 mg Injection 4 ml is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelClozapine
Severe
DocetaxelEtanercept
Severe

Drug-Drug Interactions

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DocetaxelClozapine
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Taking RTU-Doce 80 mg Injection 4 ml and clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between RTU-Doce 80 mg Injection 4 ml and Clozapine, but it can be taken if prescribed by a doctor. If you're taking clozapine and also taking medications that can affect your bone marrow or cause agranulocytosis, be careful and get regular check-ups. If you notice any symptoms like infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain while urinating, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
DocetaxelEtanercept
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
When Etanercept is used with RTU-Doce 80 mg Injection 4 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with RTU-Doce 80 mg Injection 4 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
DocetaxelTofacitinib
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Taking Tofacitinib with RTU-Doce 80 mg Injection 4 ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and RTU-Doce 80 mg Injection 4 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelKetoconazole
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Coadministration of Ketoconazole and RTU-Doce 80 mg Injection 4 ml may significantly increase the blood levels of RTU-Doce 80 mg Injection 4 ml. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and RTU-Doce 80 mg Injection 4 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelCeritinib
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Taking ceritinib and may significantly increase the blood levels of RTU-Doce 80 mg Injection 4 ml.

How to manage the interaction:
Taking RTU-Doce 80 mg Injection 4 ml with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to a doctor.
DocetaxelCiclosporin
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Coadministration of RTU-Doce 80 mg Injection 4 ml with ciclosporin may significantly increase the blood levels of RTU-Doce 80 mg Injection 4 ml.

How to manage the interaction:
Although there is a possible interaction between deferasirox and ciclosporin, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
DocetaxelErythromycin
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Erythromycin may significantly increase RTU-Doce 80 mg Injection 4 ml blood levels. This may increase the possibility of RTU-Doce 80 mg Injection 4 ml side effects.

How to manage the interaction:
Although taking erythromycin and ceritinib together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience fatigue, confusion, unusual bruising or bleeding, fever, shivers, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, urination discomfort or burning. Do not discontinue any medications without consulting a doctor.
DocetaxelTofacitinib
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
When Tofacitinib is taken with RTU-Doce 80 mg Injection 4 ml, the body's ability to break down Tofacitinib may be reduced.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and RTU-Doce 80 mg Injection 4 ml, you can take these medicines together if prescribed by your doctor. "If you are taking tofacitinib along with other drugs that weaken your immune system, it is important to be closely monitored for any signs of infection. This includes the possibility of getting tuberculosis, even if you tested negative for it before starting the medication." Do not stop using any medications without first talking to your doctor.
DocetaxelDiltiazem
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
When Diltiazem is taken with RTU-Doce 80 mg Injection 4 ml, it can slow down the breakdown of RTU-Doce 80 mg Injection 4 ml in the body.

How to manage the interaction:
Taking Diltiazem with RTU-Doce 80 mg Injection 4 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelItraconazole
Severe
How does the drug interact with RTU-Doce 80 mg Injection 4 ml:
Coadministration of Itraconazole may significantly increase the blood levels of RTU-Doce 80 mg Injection 4 ml.

How to manage the interaction:
Although there is a possible interaction between RTU-Doce 80 mg Injection 4 ml and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

RTU-Doce 80 mg Injection 4 ml Substitute

Substitutes safety advice
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  • Adoxi 20mg Injection Combipack 0.5 ml

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Alcohol

Unsafe

It is unsafe to consume alcohol while using RTU-Doce 80 mg Injection 4 ml since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

bannner image

Pregnancy

Unsafe

It is unsafe to use RTU-Doce 80 mg Injection 4 ml in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using RTU-Doce 80 mg Injection 4 ml.

bannner image

Breast Feeding

Unsafe

RTU-Doce 80 mg Injection 4 ml is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting RTU-Doce 80 mg Injection 4 ml.

bannner image

Driving

Unsafe

RTU-Doce 80 mg Injection 4 ml causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with RTU-Doce 80 mg Injection 4 ml.

bannner image

Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with RTU-Doce 80 mg Injection 4 ml, your doctor may advise you of blood tests to check your liver functioning.

bannner image

Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting RTU-Doce 80 mg Injection 4 ml.

bannner image

Children

Unsafe

Safety and efficacy of RTU-Doce 80 mg Injection 4 ml have not been established in patients younger than 18 years.

FAQs

RTU-Doce 80 mg Injection 4 ml belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers.
RTU-Doce 80 mg Injection 4 ml contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.
RTU-Doce 80 mg Injection 4 ml should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using RTU-Doce 80 mg Injection 4 ml.
During treatment with RTU-Doce 80 mg Injection 4 ml, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.
It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.
RTU-Doce 80 mg Injection 4 ml might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, RTU-Doce 80 mg Injection 4 ml is not recommended. Please consult your doctor for more information.
RTU-Doce 80 mg Injection 4 ml is administered through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
RTU-Doce 80 mg Injection 4 ml may cause weight loss due to common side effects such as loss of appetite, nausea, vomiting, diarrhoea, and fatigue. But, in rare cases, some patients may experience fluid retention or increased hunger, which can lead to weight gain. Consult your doctor or pharmacist for personalized guidance if you have concerns about weight changes.
The duration of RTU-Doce 80 mg Injection 4 ml treatment varies depending on the type of your cancer, dose of RTU-Doce 80 mg Injection 4 ml, and your response to therapy. Typically, it is administered once every 3 weeks. Your doctor will determine the total length of treatment for you based on your specific situation.
No, it is advisable not to drink alcohol while taking RTU-Doce 80 mg Injection 4 ml. Drinking alcohol during treatment may cause increased dizziness and drowsiness.
No, RTU-Doce 80 mg Injection 4 ml is not available in pill form. It is available in two primary dosage forms: injection and powder for injection.
Before administering RTU-Doce 80 mg Injection 4 ml, certain blood tests are required to ensure safe administration. These tests include a Complete Blood Count (CBC) to check blood cell counts, blood urea nitrogen (BUN) and creatinine levels to assess kidney function, liver function tests (LFTs) to evaluate liver health, and electrolyte level checks. Additionally, other tests may be required depending on individual patient needs and medical history. These blood tests help healthcare providers assess kidney and liver function and other vital parameters to ensure that RTU-Doce 80 mg Injection 4 ml can be administered safely and effectively. Your healthcare provider will determine the necessary blood tests and monitoring requirements.
Hair loss caused by RTU-Doce 80 mg Injection 4 ml is often reversible. While RTU-Doce 80 mg Injection 4 ml can cause hair thinning or loss, hair growth returns once treatment is stopped. However, in some cases, hair loss may be permanent. Consult your healthcare provider for guidance and support if you're concerned about hair loss.
Dexamethasone is used with RTU-Doce 80 mg Injection 4 ml to avoid toxicities.
RTU-Doce 80 mg Injection 4 ml is a chemotherapy medication that belongs to the class of drugs known as anti-neoplastic/anticancer drugs. It is a cytotoxic agent that prevents the cancer cells from rapidly dividing and spreading.
RTU-Doce 80 mg Injection 4 ml causes dizziness and drowsiness that may affect your ability to drive. So, do not drive or operate machinery if you experience these.
The common side effects of RTU-Doce 80 mg Injection 4 ml may include vomiting, constipation, changes in taste, extreme tiredness, muscle, joint, or bone pain, hair loss, nail changes, increased eye tearing, sores in the mouth and throat, and redness, dryness, or swelling at the injection site. However, these symptoms usually diminish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.
RTU-Doce 80 mg Injection 4 ml is generally considered safe when following your doctor's advice. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
RTU-Doce 80 mg Injection 4 ml contains Docetaxel, which belongs to the anticancer drugs.
Safety and efficacy of RTU-Doce 80 mg Injection 4 ml have not been established in patients younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

2/236, KAMBRATH THAZAM, PULLALUR, KURUVATTOOR PO, NA KOZHIKODE Kozhikode Kerala 673012
Other Info - RTU0003

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