RPIGAT 15 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 15 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

RPIGAT 15 TABLETS contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take RPIGAT 15 TABLETS as prescribed. You are advised to take RPIGAT 15 TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of RPIGAT 15 TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to RPIGAT 15 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 15 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 15 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

RPIGAT 15 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 15 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. RPIGAT 15 TABLETS works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

• Bleeding

• Anaemia (low number of red blood cells)

• Nausea

RPIGAT 15 TABLETS should be used with caution in children. Prolonged use of RPIGAT 15 TABLETS may cause hair loss. Regular blood tests are recommended while taking RPIGAT 15 TABLETS to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to RPIGAT 15 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 15 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 15 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug-Drug Interactions: RPIGAT 15 TABLETS may interact with antiplatelet drugs (warfarin, enoxaparin), antiviral or HIV medicines (lopinavir, ritonavir), painkillers (aspirin, ibuprofen), antiepileptic drugs (carbamazepine, phenytoin), drugs to treat fungal or bacterial infections (fluconazole, erythromycin, clarithromycin), and herbal medication for depression (St John's wort).

Drug-Food Interactions: RPIGAT 15 TABLETS may interact with grapefruit juice, cranberry juice, and green tea. 

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

• WARFARIN
• ENOXAPARIN
• LOPINAVIR
• RITONAVIR
• ASPIRIN
• IBUPROFEN
• CARBAMAZEPINE
• PHENYTOIN
• ITRACONAZOLE
• KETOCONAZOLE
• FLUCONAZOLE
• ERYTHROMYCIN
• CLARITHROMYCIN

• Avoid making any changes in your diet without first talking to your doctor.

• Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with RPIGAT 15 TABLETS and lead to unwanted side effects. Hence try to avoid these juices while taking RPIGAT 15 TABLETS .

• Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR, or international normalized ratio to analyze your blood clotting time.

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling. Pulmonary embolism (blood clots in the lung) is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.