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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Rozalet 20 Capsule is used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our body. It contains Rosuvastatin and Clopidogrel, which reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina). In some cases, you may experience side effects such as headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea.
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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Rozalet 20 Capsule

Rozalet 20 Capsule is used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our body. A heart attack is a condition in which your coronary arteries (blood vessels supplying blood and oxygen to the heart) become blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Rozalet 20 Capsule is composed of two medicines, Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together, Rozalet 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina).

Take Rozalet 20 Capsule exactly as directed by your doctor. The dose and duration of Rozalet 20 Capsule may differ depending on the reason why you're taking it and your responses to treatment. In some cases, you may experience headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. Rozalet 20 Capsule is known to cause dizziness, so driving should be avoided. Most of these side effects of Rozalet 20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Rozalet 20 Capsule of your own. Suddenly, stopping Rozalet 20 Capsule may worsen your condition and increase your risk of a future heart attack. Inform your doctor if you are allergic to rosuvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor that they are taking Rozalet 20 Capsule before any surgery is scheduled or any new medicine is taken. Rosuvastatin, present in Rozalet 20 Capsule , is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the fetus if administered to pregnant or breastfeeding women.

Uses of Rozalet 20 Capsule

Treatment of Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Swallow Rozalet 20 Capsule as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Rozalet 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

How Rozalet 20 Capsule Works

Rozalet 20 Capsule is composed of two medicines, Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together, Rozalet 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rozalet 20 Capsule

  • Stomach bleeding

  • Gastrointestinal bleeding

  • Nose bleeding

  • Rash

  • Diarrhoea

  • Stomach ulcer

  • Muscle disease (myopathy, rhabdomyolysis)

  • Abdominal pain

What if I have taken an overdose of Rozalet 20 Capsule

Do not take more than the prescribed dose of Rozalet 20 Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Tell your doctor if you are allergic to rosuvastatin, clopidogrel, or any of its ingredients. If you have any active liver disease, active bleeding issues (like peptic ulcers, brain haemorrhage), pregnant, or plan to become pregnant or breastfeeding, do not take Rozalet 20 Capsule until prescribed. The patient should inform the doctor that they are taking Rozalet 20 Capsule before any surgery is scheduled or any new medicine is taken. Rosuvastatin present in Rozalet 20 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to pregnant women. The risk of muscle problems might increase if Rozalet 20 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Rozalet 20 Capsule contains rosuvastatin, which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Rozalet 20 Capsule with caution. Safety and effectiveness of Rozalet 20 Capsule have not been established, so its use should be avoided in paediatric patients less than ten years of age. Discontinuation of Rozalet 20 Capsule may lead to cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Rozalet 20 Capsule .

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
ClopidogrelMifepristone
Critical

Drug-Drug Interactions

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ClopidogrelSelexipag
Critical
How does the drug interact with Rozalet 20 Capsule 10's:
When Selexipag and Rozalet 20 Capsule 10's are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Rozalet 20 Capsule 10's with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelMifepristone
Critical
How does the drug interact with Rozalet 20 Capsule 10's:
Taking Rozalet 20 Capsule 10's together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Rozalet 20 Capsule 10's with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelTirofiban
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Taking Rozalet 20 Capsule 10's with Tirofiban can make the antiplatelet effects of Tirofiban stronger.

How to manage the interaction:
There may be a possibility of interaction between Tirofiban and Rozalet 20 Capsule 10's, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
ClopidogrelAbciximab
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Coadministration of Rozalet 20 Capsule 10's with Abciximab it increases the risk of bleeding.

How to manage the interaction:
Although there is a interaction between Rozalet 20 Capsule 10's and Abciximab, but it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, and weakness. Do not discontinue any medications without consulting your doctor.
ClopidogrelPioglitazone
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Taking Pioglitazone with Rozalet 20 Capsule 10's can increases the blood levels of Pioglitazone, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Rozalet 20 Capsule 10's together with Pioglitazone may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
ClopidogrelLoperamide
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Taking loperamide with Rozalet 20 Capsule 10's may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Rozalet 20 Capsule 10's with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
ClopidogrelRepaglinide
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Rozalet 20 Capsule 10's increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Rozalet 20 Capsule 10's with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.
ClopidogrelArgatroban
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Taking Rozalet 20 Capsule 10's together with argatroban can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Rozalet 20 Capsule 10's and Apixaban, they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medications without consulting your doctor.
ClopidogrelCangrelor
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Co-administration of Cangrelor with Rozalet 20 Capsule 10's and reduce its effectiveness if used at the same time.

How to manage the interaction:
Although taking Rozalet 20 Capsule 10's with cangrelor can result in an interaction, they can be taken together if prescribed by a doctor. Rozalet 20 Capsule 10's should be taken after the Cangrelor infusion is complete. Do not stop taking any medication without consulting a doctor.
ClopidogrelPanobinostat
Severe
How does the drug interact with Rozalet 20 Capsule 10's:
Taking Rozalet 20 Capsule 10's together with Panobinostat can increases the risk of bleeding.

How to manage the interaction:
Although taking Rozalet 20 Capsule 10's together with panobinostat can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime effectively complement treatment with Rozalet 20 Capsule .

  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish, and nuts contain too many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Rozalet 20 Capsule Substitute

Substitutes safety advice
  • Rosuvas CV 20mg/75mg Tablet 10's

    by AYUR

    22.23per tablet
  • Rosufit CV 20 Capsule 15's

    by AYUR

    28.02per tablet
  • Razel CV 20/75 Capsule 10's

    by AYUR

    23.58per tablet
  • Rosumac CV 20 Capsule 10's

    by AYUR

    27.09per tablet
  • Roseday CV 20 mg Capsule 10's

    7.83per tablet
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Alcohol

Unsafe

Rozalet 20 Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Rozalet 20 Capsule contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor might prescribe you only in an extreme case.

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Breast Feeding

Caution

Take Rozalet 20 Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Rozalet 20 Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Rozalet 20 Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rozalet 20 Capsule to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Rozalet 20 Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Rozalet 20 Capsule have not been established in children due to limited testing of Rozalet 20 Capsule on children by competent authorities worldwide.

FAQs

Rozalet 20 Capsule is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.
Rozalet 20 Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Rozalet 20 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina).
Yes, Rozalet 20 Capsule contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, preventing heart attack and stroke.
No, Rozalet 20 Capsule contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Rozalet 20 Capsule .
If you accidentally take an overdose of Rozalet 20 Capsule , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, you should immediately go to the nearby clinic or hospital.
It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.
Do not drink grapefruit juice while taking Rozalet 20 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.
Yes, prolonged use of Rozalet 20 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Rozalet 20 Capsule , consult your doctor about this issue.
Yes, taking Rozalet 20 Capsule can increase bleeding risk as it contains aspirin and clopidogrel, which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid bleeding. Before going through any surgical procedure, let your doctor know that you are taking the Rozalet 20 Capsule .
Consult the doctor before taking other medicines whilst on treatment with Rozalet 20 Capsule to prevent any interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressant.
If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking Rozalet 20 Capsule . The doctor might ask you to stop Rozalet 20 Capsule before surgery as it might increase the risk of bleeding.
Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.
It might be safe to use paracetamol while taking Rozalet 20 Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.
Side effects of Rozalet 20 Capsule include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - ROZ0167

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