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Written By Bayyarapu Mahesh Kumar , M Pharmacy

ROPIN 0.75% INJECTION is used in adults to produce local or regional anaesthesia for surgery and acute pain management. It contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain. t may occasionally cause undesirable effects during the medical procedure like hypotension, nausea, vomiting, bradycardia (slow heart rate), fever, pain, postoperative complications, anaemia, paresthesia (Pins and needles), headache, pruritus (itching), and back pain.

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Whats That

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Synonym :

ROPIVACAINE

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About ROPIN 0.75% INJECTION

ROPIN 0.75% INJECTION belongs to the class of local anaesthetic medications. It is indicated in adults for producing local or regional anaesthesia for surgery and acute pain management. Anesthesia is a medical procedure that prevents pain and discomfort during surgical or medical procedures. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. The tolerance level of pain might vary from person to person.

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION is administered only in a hospital setting by an anaesthetist. It may occasionally cause undesirable effects during the medical procedure like hypotension, nausea, vomiting, bradycardia (slow heart rate), fever, pain, postoperative complications, anaemia, paresthesia (Pins and needles), headache, pruritus (itching), and back pain. Any problems that arise during your procedure will be promptly addressed by your anaesthetist.

ROPIN 0.75% INJECTION is recommended not to use if you are hypersensitive to Ropivacaine Hydrochloride or other similar anaesthetics. So, before taking ROPIN 0.75% INJECTION, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, let your doctor know if you are pregnant or breastfeeding. The safety and efficacy of ropivacaine in pediatric patients have not been established. Patients should not drive or operate heavy machinery for at least 24 hours after receiving Ropivacaine Hydrochloride.

Uses of ROPIN 0.75% INJECTION

Used for Surgical Anesthesia and Acute Pain Management

Directions for Use

ROPIN 0.75% INJECTION is administered only in a hospital setting by an anaesthetist before a medical procedure.

Medicinal Benefits

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride, which belongs to the anaesthetics class used for surgical anaesthesia. It is indicated in adults to produce local or regional anaesthesia for surgery and acute pain management. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

How ROPIN 0.75% INJECTION Works

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ROPIN 0.75% INJECTION

  • Hypotension
  • Nausea
  • Vomiting
  • Bradycardia (slow heart rate)
  • Fever
  • Pain
  • Postoperative complications
  • Anemia
  • Paresthesia (burning and pinning sensation)
  • Headache
  • Pruritus (itching)
  • Back pain

What if I have taken an overdose of ROPIN 0.75% INJECTION

As ROPIN 0.75% INJECTION is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

ROPIN 0.75% INJECTION is not recommended in individuals with known hypersensitivity to ropivacaine or other amide-type local anaesthetic medication. So, tell your doctor about your medical conditions, sensitivities, and prescriptions. Inform your doctor if you are pregnant or breastfeeding. Ropivacaine's safety and efficacy in pediatric patients have not been established. After receiving Ropivacaine Hydrochloride, patients should not drive or operate heavy machinery for at least 24 hours. ROPIN 0.75% INJECTION may cause cardiac arrhythmia or cardiac arrest in some patients. Hence, careful monitoring is recommended during the treatment.

Drug-Drug Interactions

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RopivacaineBupivacaine
Severe
RopivacaineSulfasalazine
Severe

Drug-Drug Interactions

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RopivacaineBupivacaine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Combining Ropin 0.75% Injection 20ml with Bupivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Ropin 0.75% Injection 20ml and Bupivacaine, you can take these medicines together if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
RopivacaineSulfasalazine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Coadministration of Sulfasalazine with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Ropin 0.75% Injection 20ml and sulfasalazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RopivacaineIsosorbide dinitrate
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking isosorbide dinitrate with Ropin 0.75% Injection 20ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Ropin 0.75% Injection 20ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RopivacaineGlyceryl trinitrate
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Coadministration of Ropin 0.75% Injection 20ml and glyceryl trinitrate has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Ropin 0.75% Injection 20ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RopivacaineTrimethoprim
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Using Ropin 0.75% Injection 20ml with trimethoprim can cause higher levels of Trimethoprim in the blood.

How to manage the interaction:
Although taking Ropin 0.75% Injection 20ml and Trimethoprim together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion contact your doctor immediately. Do not stop using any medications without a doctor's advice.
RopivacaineHydroxycarbamide
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Ropin 0.75% Injection 20ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Ropin 0.75% Injection 20ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RopivacaineRasburicase
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking rasburicase with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Rasburicase and Ropin 0.75% Injection 20ml, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RopivacainePhenobarbital
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Taking Phenobarbital with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues).

How to manage the interaction:
Although taking Phenobarbital and Ropin 0.75% Injection 20ml together can cause an interaction, it can be taken if a doctor has suggested it. Seek immediate medical attention if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without a doctor's advice.
RopivacaineNitrofurantoin
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Combining Nitrofurantoin with Ropin 0.75% Injection 20ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Nitrofurantoin and Ropin 0.75% Injection 20ml, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include gray discoloration of the skin, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, and feeling anxious or confused. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
RopivacainePrimaquine
Severe
How does the drug interact with Ropin 0.75% Injection 20ml:
Co-administration of Primaquine and Ropin 0.75% Injection 20ml can induce the risk of methemoglobinemia(a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Primaquine and Ropin 0.75% Injection 20ml, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, rapid or shallow breathing, a rapid heartbeat, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

GENERAL ANESTHETICS

ROPIN 0.75% INJECTION Substitute

Substitutes safety advice
  • ROPIN 0.75% INJECTION 4ML

    by AYUR

    28.93per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption with ROPIN 0.75% INJECTION.

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Pregnancy

Caution

Inform your doctor before receiving the ROPIN 0.75% INJECTION if you are pregnant or planning to be pregnant. Your doctor will prescribe only if clinically needed if the benefits outweigh the risks.

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Breast Feeding

Caution

ROPIN 0.75% INJECTION may be excreted into the breast milk. Your doctor may suggest you stop breastfeeding for a certain period.

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Driving

Unsafe

Patients should not drive or operate heavy machinery for at least 24 hours after receiving ROPIN 0.75% INJECTION.

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Liver

Caution

Since the liver metabolizes amide-type local anaesthetics like ropivacaine, patients with liver disease should use ROPIN 0.75% INJECTION with caution, especially if they are taking repeat doses. Individuals with severe liver disease are more likely to experience toxic plasma concentrations due to their impaired ability to metabolize local anaesthetics.

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Kidney

Caution

Since the kidneys are known to excrete this medication and its metabolites, patients with impaired renal function may be more vulnerable to toxic reactions from ROPIN 0.75% INJECTION. Inform your doctor if you have kidney problems.

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Children

Caution

The safety and efficacy of ropivacaine hydrochloride in pediatric patients have not been established.

FAQs

ROPIN 0.75% INJECTION is used for Surgical Anesthesia and Acute Pain Management.

ROPIN 0.75% INJECTION contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION may affect your heart rhythm. Disturbances of the heart rhythm are very common. Your anaesthetist will quickly deal with any problems that arise during your operation.

Country of origin

INDIA

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - ROP0010

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