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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
Rioci 2.5Mg Tablet is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the lungs). It is also used to treat chronic thromboembolic pulmonary hypertension (high blood pressure in the lung arteries). Additionally, it may improve the ability to exercise in people with these conditions and may slow the worsening of symptoms in people with PAH. This medicine works by relaxing the blood vessels in the lungs. This allows blood to flow easily and lowers blood pressure.
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Composition

RIOCIGUAT-2.50MG

Manufacturer/Marketer

Msn Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Rioci 2.5Mg Tablet

Rioci 2.5Mg Tablet belongs to the class of medications called soluble guanylate cyclase stimulators. It is also used to treat adults with Pulmonary Arterial Hypertension (PAH), alone or in combination with other medications. Pulmonary hypertension is a type of high blood pressure that affects the arteries in your lungs and the right side of your heart.

Rioci 2.5Mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs. This leads to the relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Rioci 2.5Mg Tablet is taken dose and duration as advised by the doctor. Rioci 2.5Mg Tablet may be prescribed alone or in combination with other blood pressure-lowering medicines depending upon your blood pressure levels. In some cases, Rioci 2.5Mg Tablet can cause side effects like headache, diarrhoea, decreased blood pressure, dizziness, vomiting, nausea, anaemia (low number of red blood cells), gastro-oesophageal reflux disease, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have had an allergic reaction to Rioci 2.5Mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and not stop taking it suddenly without consulting your doctor. Keep your doctor informed about your health condition and all the medicines you take before taking Rioci 2.5Mg Tablet to rule out any side effects.

Uses of Rioci 2.5Mg Tablet

Treatment of Pulmonary hypertension

Medicinal Benefits

Rioci 2.5Mg Tablet  belongs to the class of medications called soluble guanylate cyclase stimulators. Cyclic guanosine monophosphate (cyclic GMP) is a substance produced in the lungs and other parts of the body by an enzyme called guanylate cyclase in response to nitric oxide. Cyclic GMP causes the blood vessels (arteries) to relax and widen. Riociguat increases guanylate cyclase activity in two ways so that more cyclic GMP is available for the blood vessels inside the lungs. This leads to relaxation or widening of those vessels. Relaxing and widening the blood vessels in the lungs decreases the pulmonary blood pressure to the heart and improves its function. This reduces blood pressure in the lungs, which generally results in the ability to be more active.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rioci 2.5Mg Tablet

  • Headache
  • Upset stomach
  • Dizziness
  • Nausea
  • Diarrhoea
  • Low blood pressure
  • Vomiting
  • Anaemia
  • Gastroesophageal reflux (known as GERD or heartburn)
  • Constipation

Drug Warnings

Inform your doctor if you have had an allergic reaction to Rioci 2.5Mg Tablet or any ingredients in it. Let your doctor know if you have any liver disease, kidney disease, heart failure, heart valve problem or history of a heart attack. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You must closely monitor your blood pressure if you have ever had a stroke, or heart attack or currently taking other blood pressure-lowering pills. Keep your doctor informed about your health condition and all the medicines you take before taking Rioci 2.5Mg Tablet to rule out any side effects. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since Rioci 2.5Mg Tablet may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Rioci 2.5Mg Tablet as it may increase the risk of low blood pressure. Rioci 2.5Mg Tablet is not recommended in patients younger than 18 years of age.

Drug Interactions

Drug-Drug Interactions: Rioci 2.5Mg Tablet may interact with diuretic medicines (e.g. spironolactone, mannitol) and antiarrhythmic medicines (e.g. sotalol). The relevance of a particular drug interaction varies from person to person. Always consult your healthcare provider before starting or stopping any medication, and also inform your doctor about all your medical conditions and ongoing therapies before prescribing this medication. Considering these, your doctor may check the drug interactions before prescribing this medication.

Drug-Food Interactions: Alcohol may increase the side effects of Rioci 2.5Mg Tablet . Hence, it is advised to limit the intake of alcohol while using Rioci 2.5Mg Tablet .

Drug-Disease Interactions: Brief your doctor if you have a medical history of hypotension, liver impairment, and renal impairment.

Drug-Drug Interactions Checker List

  • SPIRONOLACTONE
  • MANNITOL
  • SOTALOL

Habit Forming

No

Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.
  • Eat natural and healthy foods by cutting down on high-sodium processed foods.
  • Lose those extra pounds since being obese can be a risk factor for hypertension.
  • Exercise regularly to maintain good heart health.
  • Avoid smoking and alcohol intake.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time to relax and do activities you enjoy.
  • Try to include heart-healthy omega-3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Your doctor may ask you to undergo blood and urine tests if you suffer from vomiting or dehydration.
  • If you have diabetes, using Rioci 2.5Mg Tablet may affect your blood sugar levels. Inform your doctor so that you may adjust your diabetes medication accordingly.
  • Your dietician may prescribe you a suitable exercise program and diet to manage your blood pressure.
  • Your doctor may also suggest liver function tests since the Rioci 2.5Mg Tablet may cause a change in liver enzymes.
  • may adjust your diabetes medication

Disease/Condition Glossary

Pulmonary hypertension is a type of high blood pressure that affects arteries in the lungs and the heart. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.

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Alcohol

Caution

It is advised to limit alcohol intake since alcohol consumption with Rioci 2.5Mg Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Rioci 2.5Mg Tablet in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Rioci 2.5Mg Tablet in breastfeeding/nursing mothers.

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Driving

Caution

It is not known whether Rioci 2.5Mg Tablet alters the ability to drive. Do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using Rioci 2.5Mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Rioci 2.5Mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of Rioci 2.5Mg Tablet in children. Please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

MSN Laboratories Pvt.Ltd., MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA
Other Info - RIO0048

Author Details

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FAQs

Rioci 2.5Mg Tablet is used to treat pulmonary arterial hypertension (high blood pressure in the lungs).
Rioci 2.5Mg Tablet contains ‘Riociguat’. It works by relaxing the blood vessels in the lungs to allow blood to flow easily. Thereby, it increases the blood supply to the lungs.
Please do not stop using Rioci 2.5Mg Tablet without consulting your doctor on your own. Continue using Rioci 2.5Mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Rioci 2.5Mg Tablet .
Rioci 2.5Mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

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