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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Rifacept Kid-3 Tablet is an anti-tuberculosis medicine used to treat and prevent tuberculosis. This is a combination medicine which works by inhibiting the production of certain enzyme that is required for bacterial cell wall formation. Common side effects include muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach.
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Manufacturer/Marketer :

Concept Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Rifacept Kid-3 Tablet

Rifacept Kid-3 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow.

Rifacept Kid-3 Tablet is a combination of four drugs: Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the bacterial cell wall. Pyrazinamide is an antibiotic that works by stopping the growth of bacteria that cause tuberculosis. Pyridoxine hydrochloride treats nerve damage (neuritis) caused by tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria.

Your doctor will decide the dose and duration based on the severity of your disease. Common side effects of Rifacept Kid-3 Tablet include muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Avoid foods and drinks that contain histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking Rifacept Kid-3 Tablet as they may interact. Maintain a gap of one hour between Rifacept Kid-3 Tablet and antacid medicines. Rifacept Kid-3 Tablet may cause dizziness, and vision problems, so drive with caution. Let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Avoid consuming alcohol with Rifacept Kid-3 Tablet as it might lead to liver problems. Rifacept Kid-3 Tablet should be used in children only when the doctor has prescribed it.

Uses of Rifacept Kid-3 Tablet

Treatment of Tuberculosis (TB)

Directions for Use

Tablet: Take the tablet on an empty stomach, i.e., 30 minutes before food or 2 hours after food. Swallow it as a whole with a glass of water; do not chew or break the tablet.Dispersible tablet: Dissolve or disperse the tablet in a small glass of water. Drink it after the contents of the tablet are completely dispersed. For children, when prescribed, the tablet should be dispersed in a teaspoonful of water and given.

Medicinal Benefits

Rifacept Kid-3 Tablet contains Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the bacterial cell wall. Pyrazinamide is an antibiotic that works by stopping the growth of bacteria that cause tuberculosis. Pyridoxine hydrochloride (vitamin B6) treats nerve damage (neuritis) caused by tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Together, Rifacept Kid-3 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

How Rifacept Kid-3 Tablet Works

Rifacept Kid-3 Tablet is a combination of four drugs: Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the bacterial cell wall. Pyrazinamide is an antibiotic that works by stopping the growth of bacteria that cause tuberculosis. Pyridoxine hydrochloride treats nerve damage (neuritis) caused by tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rifacept Kid-3 Tablet

  • Muscle/joint pain
  • Nausea
  • Vomiting
  • Rash
  • Dark coloured urine
  • Weakness
  • Dry mouth
  • Stomach pain
  • Upset stomach 

What if I have taken an overdose of Rifacept Kid-3 Tablet

Do not take more than the prescribed dose of Rifacept Kid-3 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking Rifacept Kid-3 Tablet as they might cause interaction. Maintain a gap of one hour between Rifacept Kid-3 Tablet and antacid medicines. Consult your doctor before taking Rifacept Kid-3 Tablet if you are pregnant. Breastfeeding mothers should speak to a doctor before they take Rifacept Kid-3 Tablet since it passes into breast milk. Rifacept Kid-3 Tablet may cause dizziness, and vision problems, so drive with caution. Avoid alcohol consumption while taking Rifacept Kid-3 Tablet as it could lead to increased liver damage. Store Rifacept Kid-3 Tablet below 25°C away from direct sunlight.

Drug-Drug Interactions

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RifampicinRanolazine
Critical
RifampicinPirfenidone
Critical

Drug-Drug Interactions

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RifampicinRanolazine
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
When ranolazine is taken with Rifacept Kid-3 Tablet 10's, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rifacept Kid-3 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
Taking pirfenidone with Rifacept Kid-3 Tablet 10's can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Rifacept Kid-3 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
Taking Voriconazole with Rifacept Kid-3 Tablet 10's can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Rifacept Kid-3 Tablet 10's, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinIndinavir
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
When Indinavir is taken with Rifacept Kid-3 Tablet 10's, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rifacept Kid-3 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDarunavir
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
Taking darunavir with Rifacept Kid-3 Tablet 10's can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rifacept Kid-3 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
Taking saquinavir with Rifacept Kid-3 Tablet 10's can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rifacept Kid-3 Tablet 10's, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
When Lovastatin is taken with Rifacept Kid-3 Tablet 10's, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Rifacept Kid-3 Tablet 10's with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidRegorafenib
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
When Rifacept Kid-3 Tablet 10's is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Rifacept Kid-3 Tablet 10's is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidLomitapide
Critical
How does the drug interact with Rifacept Kid-3 Tablet 10's:
When Lomitapide is taken with Rifacept Kid-3 Tablet 10's, Rifacept Kid-3 Tablet 10's may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Rifacept Kid-3 Tablet 10's with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
PyrazinamideKetoconazole
Severe
How does the drug interact with Rifacept Kid-3 Tablet 10's:
Co-administration of Ketoconazole with Rifacept Kid-3 Tablet 10's may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Rifacept Kid-3 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS
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Alcohol

Unsafe

Avoid alcohol consumption while taking Rifacept Kid-3 Tablet . Alcohol intake, along with Rifacept Kid-3 Tablet , may cause increased liver damage. Please consult your doctor for more information.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, or planning a pregnancy; your doctor will prescribe Rifacept Kid-3 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Rifacept Kid-3 Tablet is not recommended for use during breastfeeding since it is excreted into the breast milk and may harm your baby. However, please consult your doctor before taking Rifacept Kid-3 Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Rifacept Kid-3 Tablet may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Please consult your doctor since Rifacept Kid-3 Tablet should be used with caution in patients with liver impairment/liver disease. Regular monitoring of liver function tests is also advised.

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Kidney

Caution

Please consult your doctor since Rifacept Kid-3 Tablet should be used with caution in patients with kidney impairment/kidney disease. Your doctor may adjust the dosage in case of renal dysfunction.

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Children

Safe if prescribed

Rifacept Kid-3 Tablet is recommended in children only when the doctor has prescribed it.

FAQs

Rifacept Kid-3 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow.
Rifacept Kid-3 Tablet contains Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Rifacept Kid-3 Tablet interferes with the growth of tuberculosis causing bacteria and killing them. Thus Rifacept Kid-3 Tablet effectively treats TB (tuberculosis).
Rifacept Kid-3 Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking Rifacept Kid-3 Tablet . Do not worry, as it is a common side-effect of Rifacept Kid-3 Tablet .
Rifacept Kid-3 Tablet can affect live vaccines like typhoid vaccine and decrease their effectiveness. Therefore, please consult a doctor before you start using Rifacept Kid-3 Tablet if you are about to undergo any vaccinations.
Take the missed dose of Rifacept Kid-3 Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.
Yes, Rifacept Kid-3 Tablet may decrease the effectiveness of contraceptive pills. Rifampicin in Rifacept Kid-3 Tablet decreases the hormones essential for birth control in females taking contraceptive pills. It induces the enzyme in the liver that speeds up the metabolism of the hormones. Therefore, please discuss with your doctor and use an alternative contraception method while taking Rifacept Kid-3 Tablet .
Serious side effects of Rifacept Kid-3 Tablet include swelling of tongue, lips, throat, and difficulty in breathing. Also, it can cause rare side effects such as flu-like symptoms, sore throat, and joint pains. However, if you experience such effects, contact your doctor immediately.

Country of origin

INDIA

Manufacturer/Marketer address

Plot no: 492, Viduthalai Nagar Extension Near JD Mahal, Pallavaram Thuraipakam Road S.Kulathur,Kovilambakkam, Chennai - 600 117
Other Info - RIF0017

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