RIFA 1 6 TABLET belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. RIFA 1 6 TABLET is also used in the treatment of leprosy (infectious disease-causing skin lesions and nerve damage), legionnaires disease (a type of pneumonia caused by legionella bacteria), brucellosis (bacterial infection), and serious staphylococcal infections.

RIFA 1 6 TABLET is a combination of three drugs, namely: Rifampicin, Pyridoxine (vitamin B6), and Isoniazid. Rifampicin works by inactivating a bacterial RNA-polymerase, an enzyme that allows TB bacteria to make and replicate essential proteins. Isoniazid prevents the creation of its protective coating by these bacteria. Together, they destroy the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), and the infection is eliminated. Vitamin B6 treats nerve damage (neuritis) caused by tuberculosis (TB), treating drugs like isoniazid.

Take RIFA 1 6 TABLET as prescribed. The dose and duration of RIFA 1 6 TABLET can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects such as severe diarrhea, possibly with blood in the stools, hypertension, kidney problems, severe stomach pain, mental disturbances, constipation, dry mouth, and upset stomach. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not stop taking RIFA 1 6 TABLET despite symptomatic relief. Treat your condition effectually. Continue taking RIFA 1 6 TABLET for as long as it has been prescribed for you. Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking RIFA 1 6 TABLET as they might cause interaction. Maintain a gap of one hour between RIFA 1 6 TABLET and antacid medicines. Consult your doctor before taking RIFA 1 6 TABLET if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RIFA 1 6 TABLET as it passes into breast milk. RIFA 1 6 TABLET may cause dizziness, and vision problems, so drive with caution. Avoid alcohol consumption while taking RIFA 1 6 TABLET as it could lead to increased drowsiness, dizziness, and liver damage. RIFA 1 6 TABLET may make the 'contraceptive pill” less effective. So, use a reliable barrier method of contraception such as condoms while on RIFA 1 6 TABLET.

RIFA 1 6 TABLET is a combination of three drugs, namely: Rifampicin, Pyridoxine, and Isoniazid. Rifampicin works by inactivating a bacterial RNA-polymerase, an enzyme that allows TB bacteria to make and replicate essential proteins. Isoniazid prevents the creation of its own protective coating by these bacteria. Together, they destroy the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), and the infection is eliminated. Pyridoxine (vitamin B6) is a water-soluble vitamin that treats and prevents nerve damage (peripheral neuritis) caused by tuberculosis (TB), treating drugs like isoniazid.

• Severe diarrhea, possibly with blood in the stools
• Hypertension
• Kidney problems
• Severe stomach pain
• Mental disturbances
• Headache
• Change in color of body fluids to orange or red
• Dark urine
• Muscle weakness
• Constipation
• Dry mouth
• Upset stomach

Do not take RIFA 1 6 TABLET if you are allergic to any of its contents, if you have jaundice, or take HIV medicines (saquinavir or ritonavir). Before starting RIFA 1 6 TABLET, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking RIFA 1 6 TABLET as they might cause interaction. Maintain a gap of one hour between RIFA 1 6 TABLET and antacid medicines. Consult your doctor before taking RIFA 1 6 TABLET if you are pregnant or planning for pregnancy as RIFA 1 6 TABLET can affect the unborn baby's growth. Avoid breastfeeding while taking RIFA 1 6 TABLET as it passes into breast milk. RIFA 1 6 TABLET is not recommended for use in children. RIFA 1 6 TABLET may cause dizziness, and drowsiness, so drive with caution. Avoid alcohol consumption while taking RIFA 1 6 TABLET as it could lead to increased drowsiness, dizziness, and liver damage.

Drug-Drug Interactions: Medicines used to thin the blood such as warfarin, medicines used for pain such as codeine, morphine, pethidine, corticosteroids used for inflammation such as hydrocortisone, betamethasone, and prednisolone, methadone used for heroin withdrawal, medicines used for cancer such as imatinib, Irinotecan used for cancer, oral contraceptives, levodopa used in the treatment of Parkinson’s disease.

Drug-Food Interactions: Do not consume alcohol while taking RIFA 1 6 TABLET as it could lead to increased dizziness and liver damage. Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking RIFA 1 6 TABLET as they might cause interaction.

Drug-Disease Interactions: Porphyria (a rare blood problem), diabetes, mental problems, kidney and liver problems.

• WARFARIN
• CODEINE
• MORPHINE
• PETHIDINE
• HYDROCORTISONE
• BETAMETHASONE
• PREDNISOLONE
• METHADONE
• IMATINIB
• IRINOTECAN
• LEVODOPA

• Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
• Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system.
• Avoid processed and fried foods.
• Warm ginger tea or warm soup can help in providing relief from cough.
• Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
• Quit smoking and avoid alcohol consumption.

• RIFA 1 6 TABLET may affect test results of blood tests such as folate, vitamin B12, and liver function tests. Inform the person doing the tests that you are taking RIFA 1 6 TABLET.
• Your doctor may advise you to get regular liver tests while taking RIFA 1 6 TABLET to check how your liver functions.

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.