Ributin Capsule belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis in individuals dealing with human immunodeficiency virus (HIV) infection. Tuberculosis (TB) is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. HIV is a virus that weakens the immune system and increases the risk of TB infection. 

Ributin Capsule consists of a drug called 'Rifabutin' that comes into 'antimycobacterial'. It works by inactivating a bacterial RNA-polymerase, an enzyme that allows TB bacteria to make and replicate essential proteins. It destroys the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis), thus treating TB infection.

Take Ributin Capsule as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. In some cases, you may experience certain common side effects such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Ributin Capsule, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, or kidney or liver problems. Consult your doctor before taking Ributin Capsule if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Ributin Capsule as it passes into breast milk. Ributin Capsule is not recommended for use in children. Ributin Capsule may cause dizziness, and vision problems, so drive with caution. Avoid alcohol consumption while taking Ributin Capsule as it could lead to increased drowsiness, dizziness, and liver damage.

Ributin Capsule is indicated in patients dealing with TB caused by HIV infection to prevent or slow down the spread of TB infection. Persons who are living with HIV infection are at risk of developing TB. This disease can quickly progress in persons whose immune system is already weakened by the HIV infection, so Ributin Capsule helps to stop the growth and spread of bacteria responsible for causing and spreading infection. It does so by stopping the synthesis of a protein required by bacteria to grow and spread rapidly. 

• Nausea (feeling sick)
• Drowsiness
• Dizziness
• Headache
• Sudden wheeziness, difficulty in breathing
• Weakness
• Fever/high temperature
• Pain in the chest
• Muscle pain 
• Skin rash
• Heartburn 
• Diarrhea
• Gas
• Numbness 

A Ributin Capsule may raise your liver enzymes like ALT and cause jaundice if taken for a longer duration. So, a regular liver function test (LFT) is recommended while taking treatment with Ributin Capsule. Maintain a gap of one hour between Ributin Capsule and antacid medicines. Do not take Ributin Capsule if you are allergic to any of its contents if you have jaundice or take HIV medicines (saquinavir or ritonavir). Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking Ributin Capsule as they might cause interaction. Ributin Capsule may affect the action of some bacterial vaccines like typhoid vaccine, so it is suggested to don't go for any vaccination unless your doctor has suggested you do so.

Drug-Drug interactions: Ributin Capsule may have interaction with anti-HIV (saquinavir, ritonavir), pain killer (acetaminophen, hydrocodone), anti-depressant (duloxetine, bupropion), calcium channel blocker (diltiazem), anti-TB (ethambutol, pyrazinamide), and vitamins (ergocalciferol, cholecalciferol).

Drug-Food interactions: Do not consume alcohol while taking Ributin Capsule as it could lead to increased dizziness and liver damage. Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while taking Ributin Capsule as they might cause interaction.

Drug-Disease interactions: Ributin Capsule may have interactions with colitis (inflammation in the lining of the colon), peripheral neuropathy (numbness and pain in hands and feet), porphyria, hemodialysis, liver toxicity, kidney, and liver dysfunction.

• ACETAMINOPHEN
• HYDROCODONE
• CHOLECALCIFEROL
• DULOXETINE
• PYRAZINAMIDE
• ERGOCALCIFEROL
• ETHAMBUTOL
• BUPROPION
• DILTIAZEM
• RITONAVIR
• SAQUINAVIR

• Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
• Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
• Avoid processed and fried foods.
• Warm ginger tea or warm soup can help in providing relief from cough.
• Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
• Quit smoking and avoid alcohol consumption.

• Ributin Capsule may affect test results of blood tests such as folate, vitamin B12, and liver function tests. Inform the person doing the tests that you are taking Ributin Capsule.
• Your doctor may advise you to get regular liver tests while taking Ributin Capsule to check your liver functions.

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite, and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

HIV: It is a virus that weakens and damages the immune system of the body. The body's immune system helps the body fight infection, so weaken the immune system can put a person at high risk of other infections and diseases like TB. This virus is spread by contact with the body fluids of HIV-affected persons to healthy individuals, mostly during unprotected sex,  sharing blood, or injection.