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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Retrolam 150mg Tablet is used to control HIV infection and chronic hepatitis B. It contains Lamivudine, which prevents the virus from producing new viruses. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection. It may cause side effects such as headaches, fever, nausea, weakness, diarrhoea, cough, and runny nose.
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Prescription drug

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Composition

LAMIVUDINE-150MG

Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Retrolam 150mg Tablet

Retrolam 150mg Tablet belongs to the group of medications called antiretroviral drugs used to control HIV infection and chronic hepatitis B. Human immunodeficiency virus (HIV) is a sexually transmitted infection that, over time, leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Retrolam 150mg Tablet contains ‘lamivudine’, which is a ‘nucleotide reverse transcriptase inhibitor’ and works by preventing the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Take Retrolam 150mg Tablet as prescribed by your doctor. Your doctor will recommend how often you take Retrolam 150mg Tablet based on your medical condition. Some people may experience headaches, fever, nausea, weakness, diarrhoea, cough, and runny nose. Most of these side effects of Retrolam 150mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Retrolam 150mg Tablet if you are allergic to ‘lamivudine’ or any other contents present in it. Patients should take necessary precautions to avoid infecting others. This medicine should not be given to adolescents with a history of kidney failure. If you have liver disease, including hepatitis B or C, then you should not take this Retrolam 150mg Tablet. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects.

Uses of Retrolam 150mg Tablet

Treatment of HIV, Chronic hepatitis B

Medicinal Benefits

Retrolam 150mg Tablet belongs to the group of antiretroviral drugs used to control HIV infection and chronic hepatitis B. Retrolam 150mg Tablet contains ‘lamivudine’, which is a ‘nucleotide reverse transcriptase inhibitor’ and works by preventing the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Directions for Use

Your doctor determines the dose of Retrolam 150mg Tablet and duration to be taken. Swallow the medicines as a whole with a glass of water. Do not crush, chew, or break it. You can take medicine with or without food. Take the medication at a fixed time every day. Do not abruptly stop the medication even if your symptoms get better.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Retrolam 150mg Tablet

  • Headache
  • Fever
  • Nausea
  • Weakness
  • Diarrhea
  • Cough
  • Runny nose

 

Drug Warnings

Do not take Retrolam 150mg Tablet if you are allergic to ‘lamivudine’ or any other contents present in it. Patients should take necessary precautions to avoid infecting others. This medicine should not be given to adolescents with a history of kidney failure. If you have liver disease, including hepatitis B or C, then you should not take this Retrolam 150mg Tablet. Hepatitis B has gotten worse when this Retrolam 150mg Tablet was stopped in some people with hepatitis B. If you are overweight, especially women, do not take this Retrolam 150mg Tablet. Inform your doctor if you have never had hepatitis care before. This medicine contains lactose, so inform your doctor if you have an intolerance to any sugars. People with lactose intolerance Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects.

Drug Interactions

Drug-Drug Interactions: Retrolam 150mg Tablet may interact with a medication used to treat hepatitis B virus (adefovir dipivoxil), used to treat HIV infection (emtricitabine), antibiotic (cotrimoxazole), anticancer (cladribine, bexarotene), anti-gout medicine (leflunomide).

Drug-food interactions: No interactions found.

Drug-disease interactions: Retrolam 150mg Tablet should be used with caution in patients with pancreatic, severe liver, or kidney diseases.

Drug-Drug Interactions Checker List

  • ADEFOVIR
  • COTRIMOXAZOLE
  • CLADRIBINE
  • BEXAROTENE
  • LEFLUNOMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.

  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.

  • Avoid acidic foods such as tomatoes, lemons, and oranges.

  • Limit alcohol intake and quit smoking.

  • Exercise regularly as it promotes both physical and mental health.

  • Take the necessary precautions to avoid the spread of infection to other people.

Special Advise

Your doctor may regularly monitor liver function, kidney function, and bone density if you take Retrolam 150mg Tablet.

Disease/Condition Glossary

Human immunodeficiency syndrome (HIV): It is a virus that suppresses the immune system and causes acquired immunodeficiency syndrome (AIDS) over time. The suppression of immunity leads to the development of opportunistic infections. It is a life-long condition, and there is no permanent cure. The treatment (antiretroviral therapy) is given to suppress the infection.

Chronic Hepatitis B: A severe and long-term liver infection caused by the hepatitis B virus (HBV). It spreads by contact with infected body fluids. The symptoms of this condition are abdominal pain, dark urine, and yellowing of the eyes.

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Alcohol

Caution

Consuming alcohol while using Retrolam 150mg Tablet may worsen the condition.

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Pregnancy

Caution

Retrolam 150mg Tablet is a category B medicine. If you are pregnant, consult your doctor before taking this medicine. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Women who are HIV-positive must not breastfeed, because HIV infection can be passed on to the baby in breast milk. A small amount of Retrolam 150mg Tablet can also pass with breast milk.

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Driving

Caution

Retrolam 150mg Tablet may cause dizziness. So, avoid driving or refrain from any activities that require you to be alert mentally.

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Liver

Caution

Retrolam 150mg Tablet should be used with caution if you have liver problems. Your doctor may adjust the dose of Retrolam 150mg Tablet based on your condition.

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Kidney

Caution

Retrolam 150mg Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of Retrolam 150mg Tablet based on your condition.

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Children

Caution

Retrolam 150mg Tablet should be used with caution in children below 2 years of age.

Other Info - RETR619

Author Details

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FAQs

Retrolam 150mg Tablet is used to control HIV infection and chronic hepatitis B.
Retrolam 150mg Tablet does not affect fertility. However, if you develop any side effects while using Retrolam 150mg Tablet, consult your doctor immediately.
No, Retrolam 150mg Tablet does not cure hepatitis B but may improve the condition of the liver. It may reduce the quantity of hepatitis B virus (HBV) in the body. This is done by reducing the ability of HBV to multiply and further contaminate new liver cells.
Retrolam 150mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any side effects disturb you.
Do not stop taking Retrolam 150mg Tablet without consulting your doctor. Stopping Retrolam 150mg Tablet before treatment may worsen your hepatitis. This can occur during the first few months after you stop taking Retrolam 150mg Tablet. Take the Retrolam 150mg Tablet strictly as instructed, and do not miss any dose.
In hepatitis B (HBV) patients diagnosed with HIV, Retrolam 150mg Tablet is not suggested until and unless these patients start taking Retrolam 150mg Tablet for HIV management. Starting Retrolam 150mg Tablet in such patients may lead to resistance to the recommended HIV medicines. Therefore, doctors advise tests for HIV in patients diagnosed with HBV infection before starting treatment with Retrolam 150mg Tablet.
Do not stop taking Retrolam 150mg Tablet without the doctor’s approval. Your condition may worsen when you stop taking Retrolam 150mg Tablet.Therefore, consult the doctor before you stop taking Retrolam 150mg Tablet.
No, Retrolam 150mg Tablet is not an antibiotic. It is an antiretroviral drug which belongs to the group of medicines called nucleotides reverse transcriptase inhibitors (NRTIs) used to treat HIV infection and chronic hepatitis B virus infection.
The side effects of Retrolam 150mg Tablet include headache, fever, nausea, weakness, diarrhoea, cough and runny nose. Consult the doctor if any of these side effects persist or worsen.

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