apollo
0
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:44 PM IST

Retolon Injection is used to treat Bleeding oesophageal varices. It contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting their flow. Thus, it helps to control bleeding.

Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition :

TERLIPRESSIN-1MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Retolon Injection

Retolon Injection belongs to the class of drugs called vasopressin receptor agonists used for the treatment of bleeding oesophageal varices and the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver). Bleeding oesophageal varices occur when there is bleeding from dilated veins in the food pipe leading to your stomach.

Retolon Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

Retolon Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Retolon Injection may cause common side effects such as headache, diarrhoea, abdominal cramps, high or low blood pressure, too slow heart rate, pale skin, and insufficient blood circulation in arms, legs and skin. Most of these side effects of Retolon Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Terlipressin or other medicines, please tell your doctor. Retolon Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Retolon Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Retolon Injection.

Uses of Retolon Injection

Treatment of Bleeding oesophageal varices

Medicinal Benefits

Retolon Injection contains Terlipressin used for the treatment of bleeding oesophageal varices. It narrows the affected blood vessels and restricts the blood flow through them. Thus, it helps to control bleeding. Also, it is used for the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver).

Side Effects of Retolon Injection

  • Headache
  • Diarrhoea
  • Abdominal cramps
  • High or low blood pressure
  • Too slow heart rate
  • Pale skin
  • Insufficient blood circulation in arms, legs and skin

Directions for Use

Retolon Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Terlipressin or any other medicines, please tell your doctor. Retolon Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Retolon Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Retolon Injection. If you experience dizziness, lightheadedness, or feeling faint, inform your doctor, as these could be signs of a low heart rate. Your heart and blood circulation will be monitored continuously while on treatment with Retolon Injection.

Therapeutic Class

VASOACTIVE DRUG

Diet & Lifestyle Advise

  • Eat a balanced diet consisting of whole grains, lean protein, low salt, fruits, and vegetables.
  • Maintain a healthy weight.
  • Avoid alcohol consumption.
  • Lower your risk for hepatitis (inflammation of the liver) by practising safer sex. Avoid sharing razors or needles, and avoid contact with the blood and other bodily fluids of a person who has hepatitis.

Habit Forming

No

How Retolon Injection Works

Retolon Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

What if I have taken an overdose of Retolon Injection

Since Retolon Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
bannner image

Alcohol

Consult your doctor

The interaction of Retolon Injection with alcohol is unknown. Therefore, if you have any concerns regarding this, please discuss them with your doctor.

bannner image

Pregnancy

Consult your doctor

Limited data available on the effect of Retolon Injection on pregnant women. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Retolon Injection. Your doctor may give this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Consult your doctor

It is unknown whether Terlipressin is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Retolon Injection. Your doctor may give this medicine if the benefits outweigh the risks.

bannner image

Driving

Caution

Limited information is available. However, if you are unwell after receiving Retolon Injection, avoid driving or operating machinery.

bannner image

Liver

Consult your doctor

If you have any liver problems, inform your doctor before receiving Retolon Injection.

bannner image

Kidney

Caution

Retolon Injection should be used with caution in patients with long-standing kidney failure. Also, inform your doctor if you have impaired kidney function.

bannner image

Children

Unsafe

Retolon Injection is not recommended for children and adolescents as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

B-9, SCO 194-195, Ansal Sampark-I, Sector 5, Panchkula (HR) Chandigarh
Other Info - RE58358

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Retolon Injection is used to treat Bleeding oesophageal varices.
Retolon Injection contains Terlipressin, a synthetic pituitary hormone that works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.
You are recommended to consult a doctor before taking quinidine while on treatment with Retolon Injection as it may increase the risk or severity of QT prolongation (a heart rhythm disorder). Therefore, please consult a doctor before taking other medicines with Retolon Injection.
Retolon Injection may cause headaches as a common side effect. However, if the condition persists or worsens, please inform your doctor.
The side effects of Retolon Injection include abdominal cramps, diarrhoea, high or low blood pressure, slow heart rate, headache, pale skin, and insufficient blood circulation in arms, legs and skin. Consult the doctor if any of these symptoms persist or worsen.
Retolon Injection should not be taken if you are allergic to any of its ingredients, experiencing hypoxia (low levels of oxygen) or worsening respiratory symptoms, or have ongoing coronary, peripheral, or mesenteric ischemia (conditions affecting blood flow).
Before taking Retolon Injection, let your doctor know if you have severe bleeding in the oesophagus (food pipe). If you have a severe infection like septic shock, breathing issues such as asthma, uncontrolled high blood pressure, heart problems (angina, arrhythmias, or a history of heart attack), poor blood circulation (to the brain or limbs), kidney impairment, electrolyte imbalances, significant fluid or blood loss, if you are pregnant, or are over 70 years old.
Retolon Injection will be given as a continuous intravenous infusion by the doctor or nurse. Do not self-administer.
Retolon Injection is not recommended for children as its safety and effectiveness were not established.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.